Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Brigitte M.T. Hougardy"'
Autor:
Brigitte M.T. Hougardy, Ate G.J. van der Zee, Harry Hollema, Elisabeth G.E. de Vries, Klaske A. ten Hoor, Nathalie Reesink-Peters, Steven de Jong, Fiona A.J. van den Heuvel
Publikováno v:
International Journal of Cancer, 123(6), 1457-1465. Wiley
Development of medical therapies for high-grade cervical intraepithelial neoplasia (CIN II/III) is hampered by the lack of CIN II/III cell lines. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis upon binding to its re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa918573ffdeb3a425cf88de129caed8
https://doi.org/10.1002/ijc.23684
https://doi.org/10.1002/ijc.23684
Autor:
Steven de Jong, Elisabeth G.E. de Vries, Derk Jan A. de Groot, John H. Maduro, Fiona A.J. van den Heuvel, Brigitte M.T. Hougardy, Ate G.J. van der Zee
Publikováno v:
International Journal of Cancer. 118:1892-1900
In cervical carcinogenesis, the p53 tumor suppressor pathway is disrupted by HPV (human papilloma virus) E6 oncogene expression. E6 targets p53 for rapid proteasome-mediated degradation. We therefore investigated whether proteasome inhibition by MG13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a434c827ecf1c18be4c1150ca041dc82
https://doi.org/10.1002/ijc.21580
https://doi.org/10.1002/ijc.21580
Autor:
Elisabeth G.E. de Vries, Brigitte M.T. Hougardy, Fiona A.J. van den Heuvel, Ate G.J. van der Zee, Tineke Timmer, Steven de Jong
Publikováno v:
Gynecologic Oncology, 97(2), 353-364. ACADEMIC PRESS INC ELSEVIER SCIENCE
Objective. Binding of Fas ligand or agonistic anti-Fas antibody to the death receptor Fas can activate a caspase-cascade resulting in apoptosis. In the present study, the functionality of the Fas pathway was studied in human cervical cancer cells wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07aaa809a1f4db912f2f2ab55305650b
https://hdl.handle.net/11370/40cf9ad1-ed7a-4ffa-842c-ab93a1fede79
https://hdl.handle.net/11370/40cf9ad1-ed7a-4ffa-842c-ab93a1fede79
Autor:
Elisabeth G.E. de Vries, Gert Jan Meersma, Brigitte M.T. Hougardy, Ate G.J. van der Zee, Shinta Tan, Steven de Jong, Bessel Schaap
Publikováno v:
Molecular Pharmacology, 81(5), 701-709. AMER SOC PHARMACOLOGY EXPERIMENTAL THERAPEUTICS
In cervical cancer, the p53 and retinoblastoma (pRb) tumor suppressor pathways are disrupted by the human papilloma virus (HPV) E6 and E7 oncoproteins, because E6 targets p53 and E7 targets pRb for rapid proteasome-mediated degradation. We have inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91d7e18498be267782a624c19917bc77
https://pubmed.ncbi.nlm.nih.gov/22328720
https://pubmed.ncbi.nlm.nih.gov/22328720
Autor:
John H. Maduro, Elisabeth G.E. de Vries, Brigitte M.T. Hougardy, Ate G.J. van der Zee, Gert-Jan Meersma, Steven de Jong
Publikováno v:
International Journal of Radiation Oncology Biology Physics, 72(2), 543-552. ELSEVIER SCIENCE INC
Purpose: To investigate the potential of irradiation in combination with drugs targeting the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor (DR)4 and DR5 and their mechanism of action in a cervical cancer cell line.Met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc2687db6e086d6f366429b847768d9
https://pubmed.ncbi.nlm.nih.gov/18793956
https://pubmed.ncbi.nlm.nih.gov/18793956
Autor:
Elisabeth G.E. de Vries, Pax H.B. Willemse, Steven de Jong, Brigitte M.T. Hougardy, John H. Maduro, Ate G.J. van der Zee
Publikováno v:
The Lancet. Oncology. 6(8)
Cervical cancer is the most common gynaecological malignant disorder worldwide. The best possible treatment of locally advanced cervical cancer is a combination of radiation and cisplatin-based chemotherapy. However, 5-year overall survival is still
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbab446979f47e9de85a0a093902c52
https://pubmed.ncbi.nlm.nih.gov/16054570
https://pubmed.ncbi.nlm.nih.gov/16054570
Autor:
Brigitte M.T. Hougardy, K. A. ten Hoor, E.G.E. de Vries, Nathalie Reesink-Peters, F A J van den Heuvel, Harmen Hollema, van der Aukje Zee, Hendrika Boezen, S de Jong
Publikováno v:
Gynecologic Oncology, 96(3), 705-713. ACADEMIC PRESS INC ELSEVIER SCIENCE
OBJECTIVE: Increasing imbalance between proliferation and apoptosis is important in cervical carcinogenesis. The death ligands FasL and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induce apoptosis by binding to their cognate cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d32631c5570fd67ce5aa538275799a
https://research.rug.nl/en/publications/882c6d66-2041-4da8-b4c6-94abbbb2fcdb
https://research.rug.nl/en/publications/882c6d66-2041-4da8-b4c6-94abbbb2fcdb
