Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Brigitte Lucas-Heron"'
Autor:
Brigitte Lucas-Heron
Publikováno v:
Biochemical and Biophysical Research Communications. 225:701-704
We studied the effect of mitochondrial extracts from skeletal muscle of patients with Duchenne's muscular dystrophy (DMD) on calmitine from the skeletal muscle of normal mice and control subjects. Our results clearly show the existence of an abnormal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763ad3c724186eb2e7ef3332a7a899bf
https://doi.org/10.1006/bbrc.1996.1238
https://doi.org/10.1006/bbrc.1996.1238
Publikováno v:
Neuroscience Letters. 169:97-100
We compared the myotoxic effect of chlorpromazine on mitochondria of gastrocnemius muscle in X-related muscular dystrophy (mdx) and control mice relative to changes in calmitine and calcium concentrations before and 3 and 6 days after a single inject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f219b8f32cd158ba355a8e92c0fac7
https://doi.org/10.1016/0304-3940(94)90365-4
https://doi.org/10.1016/0304-3940(94)90365-4
Publikováno v:
Journal of the Neurological Sciences. 118:97-100
The effect of torbafylline, a xanthine derivative (Hoechst, Werk Albert, Wiesbaden, Germany), was tested relative to changes in degeneration and subsequent regeneration processes in mouse gastrocnemius muscle induced by a single injection of chlorpro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed37bcbc2bfb62f1f62f8f19cee7cbbf
https://doi.org/10.1016/0022-510x(93)90253-u
https://doi.org/10.1016/0022-510x(93)90253-u
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 104:389-393
1. Calmitine and mitochondrial calcium were studied after injection of chlorpromazine into control and denervated gastrocnemius muscle in rat. 2. Calmitine decreased under the effect of chlorpromazine and then increased again. Regenerative capacity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d891637f7b808e99be8baca85ec22462
https://doi.org/10.1016/0742-8413(93)90006-7
https://doi.org/10.1016/0742-8413(93)90006-7
Publikováno v:
Journal of the Neurological Sciences. 105:44-48
We studied experimental models capable of showing muscle degeneration and subsequent regeneration and observed the changes in calmitine, calcium uptake and calcium concentration in mitochondria during these processes. The results presented here are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ebb83ca4120bdd9317e43632b20982
https://doi.org/10.1016/0022-510x(91)90116-o
https://doi.org/10.1016/0022-510x(91)90116-o
Publikováno v:
Journal of the Neurological Sciences. 99:349-353
In our study, mitochondria were isolated from skeletal muscle in 3-, 5-, 6- and 16-week-old mdx and control mice. A deficit was observed in a calcium-specific mitochondrial protein (named "calmitine") in 3-, 5- and 6-week-old mdx mice but only in 3-w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c927bdf8aa672eb1a61eeb788e3036c
https://doi.org/10.1016/0022-510x(90)90169-n
https://doi.org/10.1016/0022-510x(90)90169-n
Publikováno v:
Neuroscience Letters. 115:103-107
Mitochondrial fractions were isolated from fast-twitch (EDL), slow-twitch (soleus) and heart muscle of normal rat (WKY). Protein separation by electrophoresis and study of calcium-45 binding showed that a specific calcium protein (designated as calmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382c8aea9a78ecc5c857cd754b71367f
https://doi.org/10.1016/0304-3940(90)90525-e
https://doi.org/10.1016/0304-3940(90)90525-e
Publikováno v:
Journal of the Neurological Sciences. 95:327-334
We isolated mitochondria from fast-twitch (extensor digitorum longus) and slow-twitch (soleus) skeletal muscle of the adult rat in normal conditions and 45 days after denervation as well as from skeletal muscle (gastrocnemius) of control and dystroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2083c1a7506cc195255157d47911f56
https://doi.org/10.1016/0022-510x(90)90078-2
https://doi.org/10.1016/0022-510x(90)90078-2
Autor:
Brigitte Lucas-Heron
Publikováno v:
Biochemical and biophysical research communications. 232(2)
This study demonstrates that the cause of calmitine deficiency in dy/dy dystrophic mice and patients with Duchenne's muscular dystrophy (DMD) is the same; i.e., the absence of an inhibitor of calmitine-specific mitochondrial protease. This inhibitor,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58260c64ca182055eeb9781bfdef44d3
https://pubmed.ncbi.nlm.nih.gov/9125222
https://pubmed.ncbi.nlm.nih.gov/9125222
Autor:
Brigitte Lucas-Heron
Publikováno v:
Biochemical and biophysical research communications. 223(1)
We studied the effect of mitochondrial extracts of skeletal muscle obtained from patients with Duchenne's muscular dystrophy (DMD) on calmitine of the mitochondrial matrix isolated from skeletal muscle of control mice. Our results in vitro clearly sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40e8cf261b41c4a93313f9dacc06e01f
https://pubmed.ncbi.nlm.nih.gov/8660374
https://pubmed.ncbi.nlm.nih.gov/8660374