Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Brigitte Kessler"'
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 8, Pp 1755-1764 (2005)
In the purple membrane (PM) of halobacteria, lipids stabilize the trimeric arrangement of bacteriorhodopsin (BR) molecules and mediate the packing of the trimers in a regular crystalline arrangement. To date, the identification and quantification of
Externí odkaz:
https://doaj.org/article/e23238dc60e84148af35e4a82565b613
Autor:
Matthias Rotheneder, Kristina Stakyte, Erik van de Logt, Joseph D. Bartho, Katja Lammens, Yilan Fan, Aaron Alt, Brigitte Kessler, Christophe Jung, Wynand P. Roos, Barbara Steigenberger, Karl-Peter Hopfner
Publikováno v:
Molecular cell.
The DNA double-strand break repair complex Mre11-Rad50-Nbs1 (MRN) detects and nucleolytically processes DNA ends, activates the ATM kinase, and tethers DNA at break sites. How MRN can act both as nuclease and scaffold protein is not well understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6f3c70745071e89e895869338498304
https://pubmed.ncbi.nlm.nih.gov/36577401
https://pubmed.ncbi.nlm.nih.gov/36577401
Autor:
Fabian, Gut, Lisa, Käshammer, Katja, Lammens, Joseph D, Bartho, Anna-Maria, Boggusch, Erik, van de Logt, Brigitte, Kessler, Karl-Peter, Hopfner
Publikováno v:
Molecular Cell. 82:3513-3522.e6
DNA double-strand breaks (DSBs) threaten genome stability and are linked to tumorigenesis in humans. Repair of DSBs requires the removal of attached proteins and hairpins through a poorly understood but physiologically critical endonuclease activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4252d02c0c76c9906126b2df56e147e4
https://doi.org/10.1016/j.molcel.2022.07.019
https://doi.org/10.1016/j.molcel.2022.07.019
Autor:
Annie Heidt, Olivier Meunier, Valérie Klein, Marie-Louise Fagherazzi, Julien Exinger, Brigitte Kessler
Publikováno v:
Revue Francophone des Laboratoires. 2019:22-29
Resume Une experience originale au laboratoire de biologie medicale du Centre Hospitalier de Haguenau a permis de definir les recommandations de bon usage des gants a usage unique dans la prise en charge des echantillons pour tous les elements de la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c60c2f87132112a8988f92b260c1c4a
https://doi.org/10.1016/s1773-035x(18)30388-5
https://doi.org/10.1016/s1773-035x(18)30388-5
Autor:
Dirk Kostrewa, Marijke Jansma, Karl-Peter Hopfner, Katja Lammens, Sebastian Eustermann, Brigitte Kessler, Christian Linke-Winnebeck, Kristina Stakyte, Claudia Litz
Publikováno v:
Structure. 28:83-95.e5
Summary Tel1 (ATM in humans) is a large kinase that resides in the cell in an autoinhibited dimeric state and upon activation orchestrates the cellular response to DNA damage. We report the structure of an endogenous Tel1 dimer from Chaetomium thermo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45943831131941fb21266e90d85fd7ed
https://doi.org/10.1016/j.str.2019.10.013
https://doi.org/10.1016/j.str.2019.10.013
Publikováno v:
Annales de biologie clinique. 73:723-727
Although many publications on the subject are available, only few campaigns for stethoscopes cleaning and disinfection are conducted. Stethoscope is a "not critical" reusable medical device and should benefit from a cleaning disinfection "low level"
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0e4f23766de8baf3c98f6c1e83b17a
https://doi.org/10.1684/abc.2015.1105
https://doi.org/10.1684/abc.2015.1105
Publikováno v:
Interbloc. 34:262-268
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bdd16b4ea4dacdeb3bbd2e130df55d7
https://doi.org/10.1016/j.bloc.2015.10.010
https://doi.org/10.1016/j.bloc.2015.10.010
Autor:
Joseph Bartho, Karl-Peter Hopfner, Jan-Hinnerk Saathoff, Brigitte Kessler, Aaron Alt, Fabian Gut, Katja Lammens, Lisa Käshammer
Publikováno v:
Molecular Cell. 76:382-394.e6
Summary DNA double-strand breaks (DSBs) threaten genome stability throughout life and are linked to tumorigenesis in humans. To initiate DSB repair by end joining or homologous recombination, the Mre11-nuclease Rad50-ATPase complex detects and proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc02b128b28ff0f86edabc3b5e6fbd2
https://doi.org/10.1016/j.molcel.2019.07.035
https://doi.org/10.1016/j.molcel.2019.07.035
The Mre11–Rad50–Nbs1 (MRN) complex is a central factor in the repair of DNA double‐strand breaks (DSBs). The ATP‐dependent mechanisms of how MRN detects and endonucleolytically processes DNA ends for the repair by microhomology‐mediated end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b10b8f1c3865e9e02ee2896f54eeeea
https://europepmc.org/articles/PMC4818761/
https://europepmc.org/articles/PMC4818761/
Autor:
Karl-Peter Hopfner, Christian B. Gerhold, Duane D. Winkler, Gregor Witte, Karolin Luger, Brigitte Kessler, Florian Seifert, K. Lakomek, Sebastian Fenn
Publikováno v:
Nucleic Acids Research
Nucleic acids research 40(21), 11036-11046 (2012). doi:10.1093/nar/gks842
Nucleic acids research 40(21), 11036-11046 (2012). doi:10.1093/nar/gks842
Nuclear actin-related proteins (Arps) are subunits of several chromatin remodelers, but their molecular functions within these complexes are unclear. We report the crystal structure of the INO80 complex subunit Arp8 in its ATP-bound form. Human Arp8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782a2bb306c7c9e41e1460b0db6e4907
https://doi.org/10.1093/nar/gks842
https://doi.org/10.1093/nar/gks842