Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Brigitte Kasper"'
Autor:
Yaqing Shu, Xiaoyang Yue, Jacqueline Wax, Brigitte Kasper, Junping Yin, Xiaoqing Wang, Liang Zhang, Marjan Ahmadi, Harald Heidecke, Antje Müller, Peter Lamprecht, Xinhua Yu, Gabriela Riemekasten, Frank Petersen
Publikováno v:
Arthritis Research & Therapy, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background Recently, a novel humanized mouse model for systemic sclerosis (SSc) was established by transferring peripheral blood mononuclear cells (PBMC) from patients with SSc to Rag2 −/− Il2rg −/− immunodeficient mice. Here, we aim
Externí odkaz:
https://doaj.org/article/cef05a485b1b4f778de006f7750dc260
Autor:
Brigitte Kasper, Xiaoyang Yue, Torsten Goldmann, Askin Gülsen, Christian Kugler, Xinhua Yu, Frank Petersen
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundIn-vitro models of differentiated primary human airway epithelial cells are a valuable tool to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Through the use of these models, it has been shown that the express
Externí odkaz:
https://doaj.org/article/aea427eda2d449609e2d46ac8018d677
Autor:
Xiaoyang Yue, Frank Petersen, Yaqing Shu, Brigitte Kasper, Junie D. Tchudjin Magatsin, Marjan Ahmadi, Junping Yin, Jacqueline Wax, Xiaoqing Wang, Harald Heidecke, Peter Lamprecht, Antje Müller, Xinhua Yu, Gabriela Riemekasten
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
ObjectiveThe contribution of sustained autologous autoantibody production by B cells to the pathogenesis of systemic sclerosis (SSc) and granulomatosis with polyangiitis (GPA) is not fully understood. To investigate this, a humanized mouse model was
Externí odkaz:
https://doaj.org/article/b0cdc854895545c19ccf2e0a848f0d4e
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
SARS-CoV-2 enters into human airway epithelial cells via membrane fusion or endocytosis, and this process is dependent on ACE2, TMPRSS2, and cathepsin L. In this study, we examined the expression profiles of the three SARS-CoV-2 entry genes in primar
Externí odkaz:
https://doaj.org/article/0caf2da6d7a74a61994d218b38b6df74
Autor:
Xiaoyang Yue, Junping Yin, Xiaoqing Wang, Harald Heidecke, Alexander Maximilian Hackel, Xiaoru Dong, Brigitte Kasper, Lifang Wen, Liang Zhang, Kai Schulze-Forster, Juliane Junker, Hanna Grasshoff, Antje Müller, Gerd Wallukat, Ingolf Schimke, Julian Zeiner, Lisa Marie Deckstein, Nicole Mertens, Anja Kerstein-Staehle, Jennifer Elisabeth Hundt, Evi Kostenis, Xinhua Yu, Gabriela Riemekasten, Frank Petersen
Publikováno v:
Annals of the rheumatic diseases.
ObjectiveTo determine contributions and functions of autoantibodies (Abs) directed to the angiotensin receptor type 1 (AT1R), which are suggested to be involved in the pathogenesis of AT1R Abs-related diseases such as systemic sclerosis (SSc).Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aceaa92cc893074d6d8f6ddda8d20e4
https://pubmed.ncbi.nlm.nih.gov/35595388
https://pubmed.ncbi.nlm.nih.gov/35595388
SARS-CoV-2 enters into human airway epithelial cells via membrane fusion or endocytosis, and this process is dependent on ACE2, TMPRSS2, and cathepsin L. In this study, we examined the expression profiles of the three SARS-CoV-2 entry-related genes i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50ada21ed836b7aacb2402c1b1f5adfc
https://doi.org/10.1101/2020.08.06.240796
https://doi.org/10.1101/2020.08.06.240796
Autor:
Gillian M. Griffiths, Udo zur Stadt, Fang Zhao, Brigitte Kasper, Jürgen Müller, Silvia Bulfone-Paus, Irm Hermans-Borgmeyer, Zane Orinska, Orietta D'Orlando
Publikováno v:
European Journal of Immunology. 43:194-208
Syntaxin 11 (STX11) controls vesicular trafficking and is a key player in exocytosis. Since Stx11 mutations are causally associated with a familial hemophagocytic lymphohistio-cytosis, we wanted to clarify whether STX11 is functionally important for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adb04fbd71afc3b76b0d59d85cc4a726
https://doi.org/10.1002/eji.201142343
https://doi.org/10.1002/eji.201142343
Autor:
Brigitte Kasper, Frank Petersen
Publikováno v:
European Journal of Cell Biology. 90:521-526
The platelet-derived chemokine CXCL4 takes a specific and unique position within the family of chemotactic cytokines. Today, much attention is directed to CXCL4's capacity to inhibit angiogenesis and to promote innate immune responses, which makes th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c613f1e327c9dd4d899ef46982a2bdcf
https://doi.org/10.1016/j.ejcb.2010.12.002
https://doi.org/10.1016/j.ejcb.2010.12.002
Autor:
Ernst Brandt, Supandi Winoto-Morbach, Brigitte Kasper, Stefan Schütze, Jessica Mittelstädt, Frank Petersen
Publikováno v:
European Journal of Immunology. 40:1162-1173
Human monocytes respond to a variety of stimuli with a complex spectrum of activities ranging from acute defense mechanisms to cell differentiation or cytokine release. However, the individual intracellular signaling pathways related to these functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50262dc79a30200bc6792e05bc86539a
https://doi.org/10.1002/eji.200939703
https://doi.org/10.1002/eji.200939703
Autor:
Brigitte Kasper, Udo zur Stadt, Florian Koch, Gudrun Nürnberg, Gritta Janka, Julia Pagel, Christian Becker, Wenke Seifert, Samantha Grieve, Stephan Ehl, Karin Beutel, Andrea Maul-Pavicic, Jan Rohr, Hans Christian Hennies, Julia Strauß, Gillian M. Griffiths
Publikováno v:
The American Journal of Human Genetics. 85:482-492
Rapid intracellular transport and secretion of cytotoxic granules through the immunological synapse requires a balanced interaction of several proteins. Disturbance of this highly regulated process underlies familial hemophagocytic lymphohistiocytosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6feb5400b7d99301a55424f7eae64765
https://doi.org/10.1016/j.ajhg.2009.09.005
https://doi.org/10.1016/j.ajhg.2009.09.005