Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Brigitte Kaluza"'
Autor:
Francesca Ros, Sonja Offner, Stefan Klostermann, Irmgard Thorey, Helmut Niersbach, Sebastian Breuer, Grit Zarnt, Stefan Lorenz, Juergen Puels, Basile Siewe, Nicole Schueler, Tajana Dragicevic, Dominique Ostler, Imke Hansen-Wester, Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Wim van Schooten, Roland Buelow, Alain C Tissot, Josef Platzer
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://doaj.org/article/eb4cfd37c8a244a096d64b9303c73a7f
Autor:
Stefan Seeber, Francesca Ros, Irmgard Thorey, Georg Tiefenthaler, Klaus Kaluza, Valeria Lifke, Jens André Alexander Fischer, Stefan Klostermann, Josef Endl, Erhard Kopetzki, Achal Pashine, Basile Siewe, Brigitte Kaluza, Josef Platzer, Sonja Offner
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://doaj.org/article/121e8ae00e8c4eaa9913c08d88a77bdd
Autor:
Klaus Kaluza, Sebastian Breuer, Roland Buelow, Grit Zarnt, Nicole Schueler, Valeria Lifke, Basile Siewe, Alain Tissot, Irmgard Thorey, Stefan Lorenz, Dominique Ostler, Josef Platzer, Brigitte Kaluza, Francesca Ros, Juergen Puels, Tajana Dragicevic, Sonja Offner, Imke Hansen-Wester, Stefan Klostermann, Helmut Niersbach, Wim Van Schooten
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Transgenic animals incorporating human antibody genes are extremely attractive for drug development because they obviate subsequent antibody humanization procedures required for therapeutic translation. Transgenic platforms have previously been estab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae469eda72b88cfe4091b276cee737e9
https://doi.org/10.1080/19420862.2020.1846900
https://doi.org/10.1080/19420862.2020.1846900
Autor:
Brigitte Kaluza
In der heutigen Reiterei spielen Zügel- und Schenkelhilfen die zentrale Rolle. Wir sehen sie als unabdingbare Notwendigkeit, auch wenn wir mehr oder weniger deutlich wahrnehmen, dass diese Reitweise das Pferd behindert und seiner Gesundheit schadet.
Autor:
Valeria Lifke, Brigitte Kaluza, Klaus Kaluza, Stefan Seeber, Sonja Offner, Georg Tiefenthaler, Basile Siewe, Josef Endl, Irmgard Thorey, Jens Fischer, Achal Pashine, Stefan Klostermann, Erhard Kopetzki, Francesca Ros, Josef Platzer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
PLoS ONE, Vol 9, Iss 2, p e86184 (2014)
We have developed a robust platform to generate and functionally characterize rabbit-derived antibodies using B cells from peripheral blood. The rapid high throughput procedure generates a diverse set of antibodies, yet requires only few animals to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3299c7a1a1864bef0db37deff810b6e9
http://europepmc.org/articles/PMC3913575
http://europepmc.org/articles/PMC3913575
Publikováno v:
Gene. 122:321-328
Chimerization of antibodies (Ab) by cloning the V (variable) regions encoding the light and heavy chains with degenerate oligodeoxyribonucleotide primers matching to framework region 1 and to the joining regions, leads to Ab with altered amino acids
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1311d044f01d2dbcdc49c7bc94dd67
https://doi.org/10.1016/0378-1119(92)90221-a
https://doi.org/10.1016/0378-1119(92)90221-a
Autor:
Eberhard Russmann, Hanno Hock, Ulrich H. Weidle, Otto Majdic, Brigitte Kaluza, Helmut Dr Rer Nat Lenz, Oliver Rentrop, Walter Knapp
Publikováno v:
Gene. 107:297-305
We have determined the sequence of the light and heavy chains of mAb 3G-10 (IgGl), a monoclonal antibody competing with interleukin 2 (IL2) for binding to the human IL2 receptor Tac protein. The antibody-encoding genes were chimerized by introducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c54249d21fc9ec416bdeb1616120a14
https://doi.org/10.1016/0378-1119(91)90330-e
https://doi.org/10.1016/0378-1119(91)90330-e
Autor:
Marina Schwirzke, Ulrich H. Weidle, Winfried Weissenhorn, Brigitte Kaluza, Elisabeth H. Weiss
Publikováno v:
Gene. 106:273-277
We describe a new method for amplification, by polymerase chain reaction (PCR), of rearranged segments encoding the variable part of light and heavy chains of an antibody (Ab) from the chromosomal DNA of hybridoma cells for the chimerizationof Abs. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a26a1e651dce94940e996ff0267419
https://doi.org/10.1016/0378-1119(91)90210-3
https://doi.org/10.1016/0378-1119(91)90210-3
Autor:
Marc Van Montagu, Ulrich H. Weidle, Anni Jacobs, Ann Depicker, Helena Van Houdt, Marc De Loose, Myriam De Neve, Brigitte Kaluza
Publikováno v:
Transgenic research. 2(4)
The yield and assembly of an IgG1 antibody and its derived F(ab) fragment were compared in Nicotiana and Arabidopsis. The results obtained showed a lot of interclonal variability. For 45% of the primary transgenic calluses, antigen-binding entities r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7d7039e2a5eb427e2ea72857e6dce16
https://pubmed.ncbi.nlm.nih.gov/8364605
https://pubmed.ncbi.nlm.nih.gov/8364605