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pro vyhledávání: '"Brigitte Jelitto"'
Autor:
Brigitte Jelitto, Michaela Capellmann, Hermann M. Bolt, Leonid I. Kirkovsky, Ulrike Hindermeier
Publikováno v:
Toxicology. 113:294-296
The acid-catalysed (perchloric acid) hydrolysis of 1,2-epoxybutene-3 (EB) and of 1,2:3,4-diepoxybutane (DEB), two reactive epoxide metabolites of 1,3-butadiene (BD), was determined based on reaction of unchanged epoxide with 1-nitro-4-pyridyl-benzene
Autor:
Hermann M. Bolt, Brigitte Jelitto
Publikováno v:
Toxicology. 113(1-3)
Male mice (B6C3F1) and male Wistar rats were exposed to [1,4-(14)C] butadiene in a closed all-glass desiccator jar system, and liver DNA was obtained. After acid hydrolysis and HPLC chromatography radioactive 7-N-(1-hydroxy-3-buten-2-yl)guanine and 7