Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Brigitte Izac"'
Autor:
Quentin Jouhault, Bilade Cherqaoui, Aude Jobart-Malfait, Simon Glatigny, Marc Lauraine, Audrey Hulot, Guillaume Morelle, Benjamin Hagege, Kétia Ermoza, Ahmed El Marjou, Brigitte Izac, Benjamin Saintpierre, Franck Letourneur, Séverine Rémy, Ignacio Anegon, Marie-Christophe Boissier, Gilles Chiocchia, Maxime Breban, Luiza M. Araujo
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
IntroductionSpondylarthritis (SpA) development in HLA-B27/human β2-microglobulin transgenic rat (B27-rat) is correlated with altered conventional dendritic cell (cDC) function that promotes an inflammatory pattern of CD4+T cells, including a biased
Externí odkaz:
https://doaj.org/article/2e30a7f06f474f3182838005f3013d7f
Single-nucleus RNA-seq and FISH identify coordinated transcriptional activity in mammalian myofibers
Autor:
Matthieu Dos Santos, Stéphanie Backer, Benjamin Saintpierre, Brigitte Izac, Muriel Andrieu, Franck Letourneur, Frederic Relaix, Athanassia Sotiropoulos, Pascal Maire
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Whether skeletal muscle fibre gene expression is coordinated as a whole in different nuclei in the fibre is unclear. Here, the authors use single nucleus RNAseq and ATACseq to show the transcriptome heterogeneity of muscle nuclei in the adult mouse f
Externí odkaz:
https://doaj.org/article/8503a3a7129146fea7a01f6be4dfc5d6
Autor:
Pierre-Yves Dumas, Cécile Naudin, Séverine Martin-Lannerée, Brigitte Izac, Luana Casetti, Olivier Mansier, Benoît Rousseau, Alexandre Artus, Mélody Dufossée, Alban Giese, Pierre Dubus, Arnaud Pigneux, Vincent Praloran, Audrey Bidet, Arnaud Villacreces, Amélie Guitart, Noël Milpied, Olivier Kosmider, Isabelle Vigon, Vanessa Desplat, Isabelle Dusanter-Fourt, Jean-Max Pasquet
Publikováno v:
Haematologica, Vol 104, Iss 10 (2019)
Internal tandem duplication in Fms-like tyrosine kinase 3 (FLT3-ITD) is the most frequent mutation observed in acute myeloid leukemia (AML) and correlates with poor prognosis. FLT3 tyrosine kinase inhibitors are promising for targeted therapy. Here,
Externí odkaz:
https://doaj.org/article/090f719244b84d939f78e91654fcc9f7
Autor:
Guillaume Beinse, Pierre-Alexandre Just, Bastien Rance, Brigitte Izac, Franck Letourneur, Nathaniel Edward Bennett Saidu, Sandrine Chouzenoux, Carole Nicco, François Goldwasser, Eric Pasmant, Frederic Batteux, Bruno Borghese, Jérôme Alexandre, Karen Leroy
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214416 (2019)
BACKGROUND:NRF2 is a major transcription factor regulating the expression of antioxidative/detoxifying enzymes, involved in oncogenic processes and drug resistance. We aimed to identify molecular alterations associated with NRF2 activation in endomet
Externí odkaz:
https://doaj.org/article/54c0304099c544f5a9dc170b02de93b5
Autor:
Pauline Rimmelé, Carolina L. Bigarella, Raymond Liang, Brigitte Izac, Rebeca Dieguez-Gonzalez, Gaetan Barbet, Michael Donovan, Carlo Brugnara, Julie M. Blander, David A. Sinclair, Saghi Ghaffari
Publikováno v:
Stem Cell Reports, Vol 3, Iss 1, Pp 44-59 (2014)
Aging hematopoietic stem cells (HSCs) exhibit defective lineage specification that is thought to be central to increased incidence of myeloid malignancies and compromised immune competence in the elderly. Mechanisms underlying these age-related defec
Externí odkaz:
https://doaj.org/article/9719d4d2a3ff4628825dd83b9f4437cd
Autor:
Elena Capel, Aldert L. Zomer, Thomas Nussbaumer, Christine Bole, Brigitte Izac, Eric Frapy, Julie Meyer, Haniaa Bouzinba-Ségard, Emmanuelle Bille, Anne Jamet, Anne Cavau, Franck Letourneur, Sandrine Bourdoulous, Thomas Rattei, Xavier Nassif, Mathieu Coureuil
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Neisseria meningitidis is a leading cause of bacterial meningitis and septicemia, affecting infants and adults worldwide. N. meningitidis is also a common inhabitant of the human nasopharynx and, as such, is highly adapted to its niche. Duri
Externí odkaz:
https://doaj.org/article/18206b351701404a886151e85e519b02
Autor:
Elena Zinovieva, Catherine Bourgain, Amir Kadi, Franck Letourneur, Brigitte Izac, Roula Said-Nahal, Nicolas Lebrun, Nicolas Cagnard, Agathe Vigier, Sébastien Jacques, Corinne Miceli-Richard, Henri-Jean Garchon, Simon Heath, Céline Charon, Delphine Bacq, Anne Boland, Diana Zelenika, Gilles Chiocchia, Maxime Breban
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000528 (2009)
Spondyloarthritis (SpA) is a chronic inflammatory disorder with a strong genetic predisposition dominated by the role of HLA-B27. However, the contribution of other genes to the disease susceptibility has been clearly demonstrated. We previously repo
Externí odkaz:
https://doaj.org/article/f1df2c2babf746f0a8c0a50ec1aac57e
Autor:
Nihel Khoudour, Florence Delestre, Fabienne Jabot–Hanin, Anne Jouinot, Juliette Nectoux, Franck Letouneur, Brigitte Izac, Michel Vidal, Loïc Guillevin, Xavier Puéchal, Pierre Charles, Benjamin Terrier, Benoit Blanchet
Publikováno v:
Arthritis & Rheumatology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fcd43af871f9c2fb4f5d1cd05bec460
https://doi.org/10.1002/art.42556
https://doi.org/10.1002/art.42556
Autor:
Anne Jouinot, Yoann Martin, Thomas Foulonneau, Yanis Bendjelal, Philip Calvet, Florian Violon, Mathilde Sibony, De Murat Daniel, Roberta Armignacco, Karine Perlemoine, Franck Letourneur, Brigitte Izac, Muriel Andrieu, Annabel Berthon, Bruno Ragazzon, Lionel Groussin, Rossella Libe, Jerome Bertherat, Guillaume Assie
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f1bcc7458b35b158630cb375423fbeed
https://doi.org/10.1530/endoabs.90.oc6.3
https://doi.org/10.1530/endoabs.90.oc6.3
Autor:
Saorin Kim, Chhayleang Kauy, Maria Dorina Bustos, Nimol Kloeung, Rotha Eam, Nimol Khim, Denis Mey Bouth, Sopheakvatey Ke, Brigitte Izac, Benoit Witkowski, Rithea Leang, Melissa Mairet-Khedim, Pascal Ringwald, Frédéric Ariey, Camille Marmai, Sophy Chy
Publikováno v:
Clinical Infectious Diseases
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases, Oxford University Press (OUP), 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases, 2021, 73 (3), pp.406-413. ⟨10.1093/cid/ciaa628⟩
Background Artesunate-amodiaquine is a potential therapy for uncomplicated malaria in Cambodia. Methods Between September 2016 and January 2017, artesunate-amodiaquine efficacy and safety were evaluated in a prospective, open-label, single-arm observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f7a408552281144c8b508c0408f3cc6
https://doi.org/10.1093/cid/ciaa628
https://doi.org/10.1093/cid/ciaa628