Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Brigitte F. Schmidt"'
Autor:
Mads Breum Larsen, Mireia Perez Verdaguer, Brigitte F Schmidt, Marcel P Bruchez, Simon C Watkins, Alexander Sorkin
Publikováno v:
eLife, Vol 8 (2019)
Previously we used gene-editing to label endogenous EGF receptor (EGFR) with GFP and demonstrate that picomolar concentrations of EGFR ligand drive signaling and endocytosis of EGFR in tumors in vivo (Pinilla-Macua et al., 2017). We now use gene-edit
Externí odkaz:
https://doaj.org/article/ff22768ff9c84a719bbb4e8178a8f07b
Autor:
Pingping Liang, Yuanying Zhang, Brigitte F Schmidt, Byron Ballou, Wei Qian, Ziyi Dong, Jiahui Wu, Lingling Wang, Marcel P Bruchez, Xiaochen Dong
Publikováno v:
Small. 19
Autor:
Dinara Bulgari, Samantha L. Cavolo, Brigitte F. Schmidt, Katherine Buchan, Marcel P. Bruchez, David L. Deitcher, Edwin S. Levitan
Neuronal dense-core vesicles (DCVs) contain neuropeptides and much larger proteins that affect synaptic growth and plasticity. Rather than using full collapse exocytosis that is common in endocrine cells, DCVs at a native intact synapse, theDrosophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::97da64bd3ae2687d717cccfea0109243
https://doi.org/10.1101/2022.12.24.521856
https://doi.org/10.1101/2022.12.24.521856
Autor:
Christopher Szent-Gyorgyi, Lydia A. Perkins, Brigitte F. Schmidt, Zhen Liu, Marcel P. Bruchez, Robert van de Weerd
Publikováno v:
ACS synthetic biology. 11(11)
A need in synthetic biology is the ability to precisely and efficiently make flexible fully designed vectors that addresses challenging cloning strategies of single plasmids that rely on combinatorial co-expression of a multitude of target and bait f
Autor:
Cheryl A. Telmer, Yi Wang, Brigitte F. Schmidt, Marcel P. Bruchez, Zhipeng Yang, M Alexandra Carpenter
Publikováno v:
ACS Chem Biol
The development and function of tissues, blood, and the immune system is dependent upon proximity for cellular recognition and communication. However, the detection of cell-to-cell contacts is limited due to a lack of reversible, quantitative probes
Autor:
Nolan M Frey, Jonathan S. Minden, Stephanie Biedka, Amber Lucas, Brigitte F. Schmidt, Sarah Boothman
Publikováno v:
J Proteome Res
Successful proteome analysis requires reliable sample preparation beginning with protein solubilization and ending with a sample free of contaminants, ready for downstream analysis. Most proteome sample preparation technologies utilize precipitation
Autor:
Alexandra N. Newby, Katherine C. Fein, Ahuja, Kolodieznyi D, Xian S, Kathryn A. Whitehead, Rebecca L. Ball, Zhang A, Berger A, Brigitte F. Schmidt, John P. Gleeson, Nicholas G. Lamson, Melamed, Silva Gl, Namit Chaudhary, Kanika Suri, Cochran K
Although oral drug delivery is preferred by patients, it is not possible for proteins because the gastrointestinal tract is not sufficiently permeable. To enable the non-toxic oral uptake of protein drugs, we investigated plant-based foods as intesti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f50fc3ca49eb64bd226f07bfc41e42
https://doi.org/10.1101/2020.03.11.987461
https://doi.org/10.1101/2020.03.11.987461
Autor:
Brigitte F. Schmidt, Marcel P. Bruchez, Qi Yan, Lydia A. Perkins, Simon C. Watkins, Mads Breum Larsen, Saumya Saurabh, Dmytro Kolodieznyi, Laura Kremer
Publikováno v:
Biochemistry 57, 861-871 (2018)
Fluorescent protein based pH sensors are a useful tool for measuring protein trafficking through pH changes associated with endo-and exocytosis. However, commonly used pH sensing probes are ubiquitously expressed with their protein of interest throug
Autor:
Marcel P. Bruchez, Brigitte F. Schmidt, Lydia A. Perkins, Gregory W. Fisher, Matharishwan Naganbabu, Frederick Mun
Publikováno v:
Molecular Pharmaceutics
The most promising F508del-CFTR corrector, VX-809, has been unsuccessful as an effective, stand-alone treatment for CF patients, but the rescue effect in combination with other drugs may confer an acceptable level of therapeutic benefit. Targeting ce
Autor:
Jonathan W. Jarvik, Lianne B. Cohen, Kalin V. Vasilev, Daniel S. Ackerman, Brigitte F. Schmidt
Publikováno v:
Bioconjugate Chemistry. 28:1356-1362
We describe proof-of-concept for a novel approach for visualizing regions of close apposition between the surfaces of living cells. A membrane-anchored protein with high affinity for a chemical ligand is expressed on the surface of one set of cells,