Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Brigitte E. Segmuller"'
Autor:
Birdella D. Kenney, Cynthia A. Maryanoff, John E. Mills, Bruce D. Harris, Rosie Chang, Roland Glaser, Frank J. Villani, Armin Roessler, Michael Breslav, Brigitte E. Segmuller
Publikováno v:
The Journal of Organic Chemistry. 72:9798-9801
An efficient process to produce kilogram quantities of a key argininylbenzo[d]thiazole intermediate was developed for the preparation of the tryptase inhibitor RWJ-56423. A variety of activated arginine esters and benzo[d]thiazole nucleophiles were e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0f0f5d000eeade988089f9f4bbf2a8
https://doi.org/10.1021/jo7019543
https://doi.org/10.1021/jo7019543
Publikováno v:
Journal of Pharmaceutical Sciences. 96:777-787
Crystalline lactose was subjected to various forms of pharmaceutical processing including compaction, lyophilization, spray drying, and cryogrinding. 13 C cross polarization and magic-angle spinning (CPMAS) NMR spectra were acquired for bulk crystall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4b65b933a70d031259803e6d4611a6
https://doi.org/10.1002/jps.20684
https://doi.org/10.1002/jps.20684
Autor:
Brigitte E. Segmuller, Setty Sundara Katugam Srinivas, Fa Zhang, Mathews Nunes, Hesse Robert Henry, Richard Dunphy
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 40:850-863
Ecalcidene (1-[(1alpha,3beta,5Z,7E,20S)-1,3-dihydroxy-24-oxo-9,10-secochola-5,7,10(19)-trien-24-yl]-piperidine) is a new 1-hydroxyvitamin D analogue. In this report, the thermal degradation, acid induced degradation and iodine induced degradation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f91f5e2551b01eb06a32cd9a773f21
https://doi.org/10.1016/j.jpba.2005.07.052
https://doi.org/10.1016/j.jpba.2005.07.052
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 23:927-937
HPLC-NMR, HPLC-MS, and HPLC-UV were used to characterize the predominant solution autoxidation and photodegradation products of ethynylestradiol (1). A hydroperoxide (2) and a series of isomeric dimeric oxidation products (3-7), were identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a498f99a7b211b8f3f0668e6bd84dd8
https://doi.org/10.1016/s0731-7085(00)00363-0
https://doi.org/10.1016/s0731-7085(00)00363-0
Publikováno v:
Synthetic Communications. 26:1775-1784
Hexamethylenetetramine/acetic anhydride-promoted α-methylenation of aryl alkyl ketones followed by acid-catalyzed cyclization of the resulting acrylophenones produce 2-alkyl indanones in excellent yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa69b8ad51dcd64cde89dcdc1891439
https://doi.org/10.1080/00397919608002617
https://doi.org/10.1080/00397919608002617
Autor:
Ann E. Polshyna, Lori Alquier, Brigitte E. Segmuller, Patrick Achord, Alan R. Oyler, Yuri V. Il’ichev, Cynthia A. Maryanoff, Yanqiu Sun, Barbara L. Armstrong, Richard Dunphy
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 59
The immunosuppressant drug rapamycin, also known as Sirolimus, underwent autoxidation under mild conditions to give numerous monomeric and oligomeric compounds, which were generally characterized by size-exclusion chromatography and NP-HPLC with UV a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68c6828576907ae9000e4d104802deef
https://pubmed.ncbi.nlm.nih.gov/22088479
https://pubmed.ncbi.nlm.nih.gov/22088479
Publikováno v:
ChemInform. 27
Hexamethylenetetramine/acetic anhydride-promoted α-methylenation of aryl alkyl ketones followed by acid-catalyzed cyclization of the resulting acrylophenones produce 2-alkyl indanones in excellent yields.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::241f257d09ccb96053f39513b9fca40e
https://doi.org/10.1002/chin.199633115
https://doi.org/10.1002/chin.199633115
Publikováno v:
Journal of the American Chemical Society. 107:1280-1285
Synthese a partir d'une cycloaddition entre le phenylseleno-2 propanal et le benzoyloxy-1 [furyl-2]-4 methoxy-4 trimethylsiloxy-2 butadiene-1,3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12225e0a3fc37fae18466d2dca3e4dcf
https://doi.org/10.1021/ja00291a030
https://doi.org/10.1021/ja00291a030
Publikováno v:
Organometallics. 2:1301-1308
Etude des pyrolyses a 150°C sous pression de 200 et 1800 psi. A 200 psi, il y a formation de Os 4 (CO) 13 (μ 3 -S) (II) Os 5 (CO) 15 (μ 4 -S) (III), et de Os 3 (CO) 9 (μ 3 -S) 2 (IV) et Os 3 (CO) 12 . Etude RX de II et III
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3811272dc366eadb653556a59d22a277
https://doi.org/10.1021/om50004a006
https://doi.org/10.1021/om50004a006
Autor:
Brigitte E. Segmuller, Donna Z. Cioffi, J. Michael McBride, Bruce A. Weber, Steven B. Bertman
Publikováno v:
Molecular Crystals and Liquid Crystals Incorporating Nonlinear Optics. 161:1-24
Although crystals of di(11-bromoundecanoyl) peroxide and di(undecanoyl) peroxide have different space groups (P43212 and C2221), the molecules pack in almost identical layers. They differ only in the nature of stacking across interfaces involving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d004115e8ea2572f41abdf51fe65f56
https://doi.org/10.1080/00268948808070236
https://doi.org/10.1080/00268948808070236