Výsledky vyhledávání - "Brigitte Deschrevel"

Functionalization of poly(lactic acid) scaffold surface by aminolysis and hyaluronan immobilization: How it affects mesenchymal stem cell proliferation

Autor: Brigitte Deschrevel, Alexandre Monnier, Kateryna Fatyeyeva, Jean-Marc Valleton, Elias Al Tawil, Quang Trong Nguyen

Publikováno v: European Polymer Journal
European Polymer Journal, Elsevier, 2018, 107, pp.202-217. ⟨10.1016/j.eurpolymj.2018.08.011⟩

Natural polymers are often used to functionalize the surface of synthetic polymer scaffolds to improve their cytocompatibility for their use as biomaterial for tissue engineering. Here we used hyaluronan (HA), a glycosaminoglycan providing essential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229c496770337220741d1f61541bdfc5
https://hal.archives-ouvertes.fr/hal-02338963

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Hyaluronidase activity is modulated by complexing with various polyelectrolytes including hyaluronan

Autor: Frédéric Tranchepain, Brigitte Deschrevel, Trias Astériou, Hélène Lenormand, Nicolas Levasseur, Jean-Claude Vincent

Publikováno v: Matrix Biology
Matrix Biology, Elsevier, 2008, 27 (3), pp.242-253. ⟨10.1016/j.matbio.2007.11.002⟩

International audience; Hyaluronidase (HAase) plays an important role in the control of the size and concentration of hyaluronan (HA) chains, whose biological properties strongly depend on their length. Our previous studies of HA hydrolysis catalyzed

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::926df90d84fe5b8aa3c893f4b10a35f3
https://doi.org/10.1016/j.matbio.2007.11.002

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Inhibition of hyaluronan hydrolysis catalysed by hyaluronidase at high substrate concentration and low ionic strength

Autor: Jean-Claude Vincent, Brigitte Deschrevel, Trias Astériou, Frédéric Tranchepain

Publikováno v: Matrix Biology. 25:166-174

Hyaluronidase and high levels of hyaluronan are found together in tumours. It is highly likely that hyaluronidase activity controls the balance between high molecular mass hyaluronan and oligosaccharides, and thus plays an important role in cancer de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26283327255c09f79d15dac485c07007
https://doi.org/10.1016/j.matbio.2005.11.005

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A complete set of hyaluronan fragments obtained from hydrolysis catalyzed by hyaluronidase: Application to studies of hyaluronan mass distribution by simple HPLC devices

Autor: Corinne Loutelier-Bourhis, Didier Le Cerf, Jean-Claude Vincent, Marie-Noëlle Courel, Brigitte Deschrevel, Frédéric Tranchepain, Nicolas Levasseur

Publikováno v: Analytical Biochemistry
Analytical Biochemistry, Elsevier Masson, 2006, 348 (2), pp.232-242. ⟨10.1016/j.ab.2005.09.042⟩

International audience; Hyaluronan (HA) has different biological functions according to its molar mass; short HA fragments are involved in inflammation processes and angiogenesis, whereas native HA is not. Physicochemically, studies of native HA hydr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b83994fe5af7388c2713065d98b1c7
https://doi.org/10.1016/j.ab.2005.09.042

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Thermodynamic parameters monitoring the equilibrium shift of enzyme-catalyzed hydrolysis/synthesis reactions in favor of synthesis in mixtures of water and organic solvent

Autor: Brigitte Deschrevel, Camille Ripoll, Jean-Claude Vincent, Michel Thellier

Publikováno v: Biotechnology and Bioengineering. 81:167-177

The main strategy developed to shift the equilibrium state of a hydrolase-catalyzed hydrolysis/synthesis reaction consists in reducing water activity by addition of organic solvents in the reaction medium. We have used several mixtures of water and 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a1ae649f54f217ba6aecf78d160f29
https://doi.org/10.1002/bit.10458

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pH effects on the hyaluronan hydrolysis catalysed by hyaluronidase in the presence of proteins: Part I. Dual aspect of the pH-dependence

Autor: Jean-Claude Vincent, Hélène Lenormand, Brigitte Deschrevel

Publikováno v: Matrix Biology
Matrix Biology, Elsevier, 2010, 29 (4), pp.330-337. ⟨10.1016/j.matbio.2009.12.007⟩

International audience; Hyaluronan (HA) hydrolysis catalysed by hyaluronidase (HAase) is strongly inhibited when performed at a low ratio of HAase to HA concentrations and at low ionic strength. This is because long HA chains can form non-active comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe19e01e65c5148a91dcafe98177035e
https://hal.archives-ouvertes.fr/hal-03266857

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Chain length effects on electrostatic interactions between hyaluronan fragments and albumin

Autor: Brigitte Deschrevel, Jean-Claude Vincent, Hélène Lenormand

Publikováno v: Carbohydrate Polymers
Carbohydrate Polymers, Elsevier, 2010, 82 (3), pp.887-894. ⟨10.1016/j.carbpol.2010.06.011⟩

International audience; We have shown that hyaluronan (HA) and bovine serum albumin (BSA) are able to form electrostatic HA-BSA complexes at pH 4, whatever the length of the HA chain over the very large domain ranging from 10 3 to 10 6 g mol −1. On

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::260a0904de22c995ea5fca9024f3a84e
https://hal.archives-ouvertes.fr/hal-03266866

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Chondroitin sulfate increases hyaluronan production by human synoviocytes through differential regulation of hyaluronan synthases: Role of p38 and Akt

Autor: Jean-Pierre Pujol, Karim Boumediene, Philippe Galéra, Brigitte Deschrevel, Maha David-Raoudi, Sylvain Leclercq

Publikováno v: Arthritis and rheumatism. 60(3)

Objective To uncover the mechanism by which chondroitin sulfate (CS) enhances hyaluronan (HA) production by human osteoarthritic (OA) fibroblast-like synoviocytes (FLS). Methods The production of HA was investigated by exposing human OA FLS to CS in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e88c35c76b959d802a94beb745b1de84
https://pubmed.ncbi.nlm.nih.gov/19248106

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The hyaluronan-protein complexes at low ionic strength: how the hyaluronidase activity is controlled by the bovine serum albumin

Autor: Frédéric Tranchepain, Hélène Lenormand, Jean-Claude Vincent, Brigitte Deschrevel

Publikováno v: Matrix Biology
Matrix Biology, Elsevier, 2009, 28 (6), pp.365-372. ⟨10.1016/j.matbio.2009.04.008⟩

International audience; Hyaluronan (HA) hydrolysis catalysed by hyaluronidase (HAase) is strongly inhibited when performed at low HAase over HA concentration ratio and under low ionic strength conditions. The reason is the ability of long HA chains t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee73729e728da13a54f1fa0828241df3
https://pubmed.ncbi.nlm.nih.gov/19394422

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Electrostatic interactions between hyaluronan and proteins at pH 4: How do they modulate hyaluronidase activity

Autor: Brigitte Deschrevel, Hélène Lenormand, Frédéric Tranchepain, Jean-Claude Vincent

Publikováno v: Biopolymers
Biopolymers, Wiley, 2008, 89 (12), pp.1088-1103. ⟨10.1002/bip.21061⟩

International audience; Hyaluronan (HA) hydrolysis catalyzed by hyaluronidase (HAase) is inhibited at low HAase over HA ratio and low ionic strength, because HA forms electrostatic complexes with HAase, which is unable to catalyze hydrolysis. Bovine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7982aeb6b453b88b2f4a9c6942047a3
https://hal.archives-ouvertes.fr/hal-03266829

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