Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Brigitte Crouau"'
Humans and Chimpanzees Display Opposite Patterns of Diversity in Arylamine N-Acetyltransferase Genes
Autor:
Christelle Vangenot, Pascal Gagneux, Natasja G. de Groot, Adrian Baumeyer, Médéric Mouterde, Brigitte Crouau-Roy, Pierre Darlu, Alicia Sanchez-Mazas, Audrey Sabbagh, Estella S. Poloni
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 9, Iss 7, Pp 2199-2224 (2019)
Among the many genes involved in the metabolism of therapeutic drugs, human arylamine N-acetyltransferases (NATs) genes have been extensively studied, due to their medical importance both in pharmacogenetics and disease epidemiology. One member of th
Externí odkaz:
https://doaj.org/article/125c54e676084809ba7d62cbc2daedc8
Autor:
Rylan Shearn, Alison E Wright, Sylvain Mousset, Corinne Régis, Simon Penel, Jean-François Lemaitre, Guillaume Douay, Brigitte Crouau-Roy, Emilie Lecompte, Gabriel AB Marais
Publikováno v:
eLife, Vol 9 (2020)
Sex chromosomes are typically comprised of a non-recombining region and a recombining pseudoautosomal region. Accurately quantifying the relative size of these regions is critical for sex-chromosome biology both from a functional and evolutionary per
Externí odkaz:
https://doaj.org/article/bf5d61d2898b4167aa525d8f1e5e5797
Autor:
Cristina B. Dejean, Brigitte Crouau-Roy, Alicia S. Goicoechea, Sergio A. Avena, Francisco R. Carnese
Publikováno v:
Genetics and Molecular Biology, Vol 27, Iss 4, Pp 489-495 (2004)
The allelic variability of four dinucleotide microsatellites located in the HLA region (MOGc, D6S265, MIB, and TNFa) was analyzed in 67 individuals representing three Amerindian populations of the Argentine Gran Chaco: Toba, Wichi and Chorote. Genomi
Externí odkaz:
https://doaj.org/article/f48d747aebc44da184bb6bc939245281
Autor:
Erwan Quéméré, Fabrice Hibert, Christian Miquel, Emeline Lhuillier, Emmanuel Rasolondraibe, Julie Champeau, Clément Rabarivola, Louis Nusbaumer, Cyrille Chatelain, Laurent Gautier, Patrick Ranirison, Brigitte Crouau-Roy, Pierre Taberlet, Lounès Chikhi
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58971 (2013)
In tropical regions, most primary ecosystems have been replaced by mosaic landscapes in which species must cope with a large shift in the distribution of their habitat and associated food resources. Primates are particularly vulnerable to habitat mod
Externí odkaz:
https://doaj.org/article/4182378996fb44209f13a85d5b8b0b76
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18507 (2011)
Arylamine N-acetyltransferase 2 (NAT2) is involved in human physiological responses to a variety of xenobiotic compounds, including common therapeutic drugs and exogenous chemicals present in the diet and the environment. Many questions remain about
Externí odkaz:
https://doaj.org/article/001ce0ea9e5241c5bd929b2d34c3c6a9
Autor:
Gaby G M Doxiadis, Corrine M C Heijmans, Maxime Bonhomme, Nel Otting, Brigitte Crouau-Roy, Ronald E Bontrop
Publikováno v:
PLoS ONE, Vol 4, Iss 1, p e4287 (2009)
In humans, the single polymorphic B locus of the major histocompatibility complex is linked to the microsatellite MIB. In rhesus macaques, however, haplotypes are characterized by the presence of unique combinations of multiple B genes, which may dis
Externí odkaz:
https://doaj.org/article/e93bf36c43814933aa326465780e0042
Autor:
Ioanna Stefani, Sofia Zaliou, Nikolaos Marinakis, Theodora Tsirka, Sophia V. Rizou, Sotiria Boukouvala, Evanthia Kontomina, Charlotte Veyssière, Brigitte Crouau-Roy, Giannoulis Fakis, Zoi Chasapopoulou, Despina Giannouri, Audrey Sabbagh
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Human NAT1 gene for N-acetyltransferase 1 modulates xenobiotic metabolism of arylamine drugs and mutagens. Beyond pharmacogenetics, NAT1 is also relevant to breast cancer. The population history of human NAT1 suggests evolution through purifying sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00aec1b9170289dd18ab6f6e3c77470d
http://link.springer.com/article/10.1038/s41598-019-47485-x
http://link.springer.com/article/10.1038/s41598-019-47485-x
Autor:
Theodora Tsirka, Charlotte Veyssière, Brigitte Crouau-Roy, Georgia Papanikolaou, Audrey Sabbagh, Nafsika Drakomathioulaki, Giannoulis Fakis, Sotiria Boukouvala
Publikováno v:
Biochemical Pharmacology. 188:114545
Human NAT2 is a polymorphic pharmacogene encoding for N-acetyltransferase 2, a hepatic enzyme active towards arylamine and arylhydrazine drugs, including the anti-tubercular antibiotic isoniazid. The isoenzyme also modulates susceptibility to chemica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aaacee9816dc9ac5fde2339669136d7
https://doi.org/10.1016/j.bcp.2021.114545
https://doi.org/10.1016/j.bcp.2021.114545
Publikováno v:
Ecology and Evolution
Ecology and Evolution, Wiley Open Access, 2016, 6 (15), pp.5517-5529. ⟨10.1002/ece3.2288⟩
Ecology and Evolution, Wiley Open Access, 2016, 6 (15), pp.5517-5529. ⟨10.1002/ece3.2288⟩
Population genetics and phenotypic structures are often predicted to vary along the geographic range of a species. This phenomenon would be accentuated for species with large range areas, with discontinuities and marginal populations. We herein compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c7e040fad4b1d141b9089f6f25e8a4a
http://europepmc.org/articles/PMC4984522
http://europepmc.org/articles/PMC4984522
Autor:
Brigitte Crouau-Roy, Simon Penel, Rylan Shearn, Sylvain Mousset, Guillaume Douay, Jean-François Lemaître, Alison E. Wright, Gabriel A. B. Marais, Corinne Régis, Emilie Lecompte
Sex chromosomes are typically comprised of a non-recombining region and a recombining pseudoautosomal region. Accurately quantifying the relative size of these regions is critical for sex chromosome biology both from a functional (i.e. number of sex-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d97334939e5825220ee57de0fd86fbe
https://doi.org/10.1101/445072
https://doi.org/10.1101/445072
