Zobrazeno 1 - 10
of 359
pro vyhledávání: '"Brigitte C, Widemann"'
Autor:
Cameron Church, Christian X. Fay, Emil Kriukov, Hui Liu, Ashley Cannon, Lauren Ashley Baldwin, David K. Crossman, Bruce Korf, Margaret R. Wallace, Andrea M. Gross, Brigitte C. Widemann, Robert A. Kesterson, Petr Baranov, Deeann Wallis
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Neurofibromatosis Type 1 (NF1) is caused by loss of function variants in the NF1 gene. Most patients with NF1 develop skin lesions called cutaneous neurofibromas (cNFs). Currently the only approved therapeutic for NF1 is selumetinib, a mitog
Externí odkaz:
https://doaj.org/article/d00a5353dd604d0dbaf40783a4391f24
Autor:
Sandra A. Mitchell, Rachael Hunter, Abigail Fry, Steven Z. Pavletic, Brigitte C. Widemann, Lori Wiener
Publikováno v:
Frontiers in Psychology, Vol 14 (2024)
BackgroundChronic graft-versus-host disease (cGVHD) is a debilitating late complication of hematopoietic stem cell transplantation. It is often accompanied by extensive symptom burden. No validated cGVHD patient-reported outcome (PRO) measure exists
Externí odkaz:
https://doaj.org/article/a833fcbf3a8c47ef92283ccc4ddf9b4d
Autor:
Sarah N. Fuller, Ahmad Shafiei, David J. Venzon, David J. Liewehr, Michal Mauda Havanuk, Maran G. Ilanchezhian, Maureen Edgerly, Victoria L. Anderson, Elliot B. Levy, Choung D. Hoang, Elizabeth C. Jones, Karlyne M. Reilly, Brigitte C. Widemann, Bradford J. Wood, Hadi Bagheri, Jaydira Del Rivero
Publikováno v:
Current Oncology, Vol 28, Iss 6, Pp 4357-4366 (2021)
Adrenocortical carcinoma (ACC) is a rare malignancy with an overall unfavorable prognosis. Clinicians treating patients with ACC have noted accelerated growth in metastatic liver lesions that requires rapid intervention compared to other metastatic l
Externí odkaz:
https://doaj.org/article/2219f8db788e4b979d9c5d218e3475d9
Autor:
Maran Ilanchezhian, Diana Grace Varghese, John W. Glod, Karlyne M. Reilly, Brigitte C. Widemann, Yves Pommier, Rosandra N. Kaplan, Jaydira Del Rivero
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy of the adrenal gland with an unfavorable prognosis. It is rare in the pediatric population, with an incidence of 0.2-0.3 patients per million in patients under 20 years old. It is primaril
Externí odkaz:
https://doaj.org/article/c2b0dfd5f57441c2b815a691d120ab2b
Autor:
Impana Shetty, Sarah Fuller, Margarita Raygada, Maria J Merino, B J Thomas, Brigitte C Widemann, Karlyne M Reilly, Karel Pacak, Jaydira Del Rivero
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2020)
Adrenocortical carcinoma (ACC) is an aggressive cancer that originates in the cortex of the adrenal gland and generally has a poor prognosis. ACC is rare but can be more commonly seen in those with cancer predisposition syndromes (e.g. Li-Fraumeni an
Externí odkaz:
https://doaj.org/article/adf5a7f1129e45ff85f598565367e689
Autor:
Yang Hou, Xian Wu, Dan Liu, Staci Martin, Mary Anne Toledo-Tamula, Taryn Allen, Andrea Baldwin, Andy Gillespie, Anne Goodwin, Brigitte C. Widemann, Pamela L. Wolters
Publikováno v:
Cancers, Vol 14, Iss 23, p 5956 (2022)
Individuals with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PNs) have a higher risk for socioemotional problems. The current study aims to identify the socioemotional developmental pattern and its predictors across childhood and adol
Externí odkaz:
https://doaj.org/article/4584f30a80d0482b8141f1d914664cf5
Autor:
Jeffrey J Szymanski, R Taylor Sundby, Paul A Jones, Divya Srihari, Noah Earland, Peter K Harris, Wenjia Feng, Faridi Qaium, Haiyan Lei, David Roberts, Michele Landeau, Jamie Bell, Yi Huang, Leah Hoffman, Melissa Spencer, Matthew B Spraker, Li Ding, Brigitte C Widemann, Jack F Shern, Angela C Hirbe, Aadel A Chaudhuri
Publikováno v:
PLoS Medicine, Vol 18, Iss 8, p e1003734 (2021)
BackgroundThe leading cause of mortality for patients with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome is the development of malignant peripheral nerve sheath tumor (MPNST), an aggressive soft tissue sarcoma. In the setting of N
Externí odkaz:
https://doaj.org/article/c4e51b3f384e4d0d940d39076a2a352f
Autor:
Robin Lockridge, Sima Bedoya, Taryn Allen, Brigitte C. Widemann, Srivandana Akshintala, John Glod, Lori Wiener
Publikováno v:
Children, Vol 9, Iss 6, p 774 (2022)
Multiple Endocrine Neoplasia type 2 (MEN2) is a genetic cancer syndrome for which there are limited data pertaining to the quality of life and psychosocial experiences of persons affected. Medullary thyroid carcinoma (MTC) is a rare disease of the th
Externí odkaz:
https://doaj.org/article/172b6c20746b404ab9bc8ffdff894948
Autor:
Catherine Lai, Diane E. Cole, Seth M. Steinberg, Nicole Lucas, Eva Dombi, Christopher Melani, Mark Roschewski, Frank Balis, Brigitte C. Widemann, Wyndham H. Wilson
Publikováno v:
Blood Advances. 7:529-532
Aggressive lymphomas are curable with doxorubicin-based chemotherapy. In patients presenting with elevated serum bilirubin, doxorubicin is commonly dose reduced or delayed based on limited pharmacokinetic data. We evaluated plasma pharmacokinetics of
Autor:
Dana C. Borcherding, Neha V. Amin, Kevin He, Xiaochun Zhang, Yang Lyu, Carina Dehner, Himanshi Bhatia, Angad Gothra, Layla Daud, Peter Ruminski, Christine A. Pratilas, Kai Pollard, Taylor Sundby, Brigitte C. Widemann, Angela C. Hirbe
Publikováno v:
Clinical Cancer Research. 29:1592-1604
Purpose: Malignant peripheral nerve sheath tumors (MPNST) are aggressive sarcomas with limited treatment options and poor survival rates. About half of MPNST cases are associated with the neurofibromatosis type 1 (NF1) cancer predisposition syndrome.