Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Brigitte Boeser-Nunnink"'
Autor:
Renée R. C. E. Schreurs, Athanasios Koulis, Thijs Booiman, Brigitte Boeser-Nunnink, Alexandra P. M. Cloherty, Anusca G. Rader, Kharishma S. Patel, Neeltje A. Kootstra, Carla M. S. Ribeiro
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Chronic HIV-1 infection is characterized by T-cell dysregulation that is partly restored by antiretroviral therapy. Autophagy is a critical regulator of T-cell function. Here, we demonstrate a protective role for autophagy in HIV-1 disease p
Externí odkaz:
https://doaj.org/article/3c90dc6926bc447289817ab4859f4bfc
Autor:
Renée Schreurs, Athanasios Koulis, Thijs Booiman, Brigitte Boeser-Nunnink, Alexandra Cloherty, Anusca Rader, Kharishma Patel, Neeltje Kootstra, Carla Ribeiro
Chronic HIV-1 infection is characterized by T-cell dysregulation that is only partly restored by antiretroviral therapy. Here, we demonstrate a protective role for autophagy in HIV-1 disease pathogenesis. Targeted analysis of genetic variation in cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc637495e5fc5835c4692f70123736be
https://doi.org/10.21203/rs.3.rs-2616340/v1
https://doi.org/10.21203/rs.3.rs-2616340/v1
Autor:
Lisa van Pul, Melissa Stunnenberg, Brigitte Boeser-Nunnink, Agnes Harskamp, Teunis Geijtenbeek, Neeltje Kootstra
Antiretroviral treatment of HIV infected individuals cannot eliminate the HIV reservoir and immune control of HIV is rarely seen upon treatment interruption. In long-term non-progressors (LTNP), an effective CD8 T cell response is thought to contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1bcda6c2e235b3351f18a75b781c2ac
https://doi.org/10.21203/rs.3.rs-2408098/v1
https://doi.org/10.21203/rs.3.rs-2408098/v1
Publikováno v:
Kruize, Z, Maurer, I, Boeser-Nunnink, B D M, Booiman, T & Kootstra, N A 2020, ' Genetic variations in the host dependency factors ALCAM and TPST2 impact HIV-1 disease progression ', AIDS (London, England), vol. 34, no. 9, pp. 1303-1312 . https://doi.org/10.1097/QAD.0000000000002540
AIDS (London, England), 34(9), 1303-1312
AIDS (London, England), 34(9), 1303-1312. Lippincott Williams and Wilkins
AIDS (London, England), 34(9), 1303-1312
AIDS (London, England), 34(9), 1303-1312. Lippincott Williams and Wilkins
OBJECTIVES: Recently, the activated leukocyte cell adhesion molecule (ALCAM) and tyrosylprotein sulfotransferase 2 (TPST2) have been identified as important host dependency factors (HDFs) for in-vitro HIV-1 replication. To determine whether these gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4a7680880ee5ca9580e05c7a2b642f
http://www.scopus.com/inward/record.url?scp=85087320665&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85087320665&partnerID=8YFLogxK
Autor:
Marit J. van Gils, Hugo D.G. van Willigen, Elke Wynberg, Alvin X. Han, Karlijn van der Straten, Judith A. Burger, Meliawati Poniman, Melissa Oomen, Khadija Tejjani, Joey H. Bouhuijs, Anouk Verveen, Romy Lebbink, Maartje Dijkstra, Brent Appelman, A.H. Ayesha Lavell, Tom G. Caniels, Ilja Bontjer, Lonneke A. van Vught, Alexander P.J. Vlaar, Jonne J. Sikkens, Marije K. Bomers, Colin A. Russell, Neeltje A. Kootstra, Rogier W. Sanders, Maria Prins, Godelieve J. de Bree, Menno D. de Jong, Ivette Agard, Jane Ayal, Anders Boyd, Floor Cavdar, Marianne Craanen, Udi Davidovich, Annemarieke Deuring, Annelies van Dijk, Ertan Ersan, Laura del Grande, Joost Hartman, Nelleke Koedoot, Tjalling Leenstra, Dominique Loomans, Agata Makowska, Tom du Maine, Ilja de Man, Amy Matser, Lizenka van der Meij, Marleen van Polanen, Maria Oud, Clark Reid, Leeann Storey, Marije de Wit, Marc van Wijk, Joyce van Assem, Joost van den Aardweg, Marijne van Beek, Thyra Blankert, Brigitte Boeser-Nunnink, Eric Moll van Charante, Karel van Dort, Orlane Figaroa, Leah Frenkel, Arginell Girigorie, Jelle van Haga, Agnes Harskamp-Holwerda, Mette Hazenberg, Soemeja Hidad, Nina de Jong, Marcel Jonges, Suzanne Jurriaans, Hans Knoop, Lara Kuijt, Anja Lok, Marga Mangas Ruiz, Irma Maurer, Pythia Nieuwkerk, Ad van Nuenen, Annelou van der Veen, Bas Verkaik, Gerben-Rienk Visser
Publikováno v:
Cell Reports Medicine, 3(1):100486. Cell Press
Cell Reports Medicine
RECoVERED Study Group 2022, ' A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern ', Cell Reports Medicine, vol. 3, no. 1, 100486 . https://doi.org/10.1016/j.xcrm.2021.100486
Cell Reports Medicine
RECoVERED Study Group 2022, ' A single mRNA vaccine dose in COVID-19 patients boosts neutralizing antibodies against SARS-CoV-2 and variants of concern ', Cell Reports Medicine, vol. 3, no. 1, 100486 . https://doi.org/10.1016/j.xcrm.2021.100486
The urgent need for, but limited availability of, SARS-CoV-2 vaccines worldwide has led to widespread consideration of dose sparing strategies. Here, we evaluate the SARS-CoV-2 specific antibody responses following BNT162b2 vaccination in 150 previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03331e82e35c017108f63a5f27a62375
http://www.scopus.com/inward/record.url?scp=85122015551&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85122015551&partnerID=8YFLogxK
Autor:
Sebastiaan M Bol, Thijs Booiman, Daniëlle van Manen, Evelien M Bunnik, Ard I van Sighem, Margit Sieberer, Brigitte Boeser-Nunnink, Frank de Wolf, Hanneke Schuitemaker, Peter Portegies, Neeltje A Kootstra, Angélique B van 't Wout
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e30990 (2012)
BACKGROUND: Infection with HIV-1 may result in severe cognitive and motor impairment, referred to as HIV-1-associated dementia (HAD). While its prevalence has dropped significantly in the era of combination antiretroviral therapy, milder neurocogniti
Externí odkaz:
https://doaj.org/article/39162ba0da244103989f1c69d89be247
Autor:
Antoinette C. van der Kuyl, Marit J. van Gils, Brigitte Boeser-Nunnink, Marion Cornelissen, Jan M. Prins, Fokla Zorgdrager, Hanneke Schuitemaker, Zelda Euler, Rogier W. Sanders, Neeltje A. Kootstra, Tom L.G.M. van den Kerkhof
Publikováno v:
AIDS research and human retroviruses, 32(10-11), 1135-1142. Mary Ann Liebert Inc.
The effect of serial HIV-1 infection on the development of the broadly neutralizing antibody (bNAb) response was studied in an individual, H01-10366, with a serial HIV-1 superinfection (SI), hence triple infection, and compared with the bNAb response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f353a216080712b9611d9b61c15c29b4
https://doi.org/10.1089/aid.2015.0324
https://doi.org/10.1089/aid.2015.0324
Autor:
Beatrice Jacquelin, Faroudy Boufassa, Simon P. Jochems, Bruno Vaslin, Nathalie Dereudre-Bosquet, Cécile Goujard, Matthew L. Albert, Thalia Garcia-Tellez, Asier Sáez-Cirión, Yoann Madec, Laurence Meyer, Caroline Passaes, Thijs Booiman, Armanda Casrouge, Nicolas Noel, Mickaël J.-Y. Ploquin, Olivier Lambotte, Camille Lécuroux, Pierre Roques, Françoise Barré-Sinoussi, Christine Rouzioux, Brigitte Boeser-Nunnink, Neeltje A. Kootstra, Gaël Petitjean, Michaela Müller-Trutwin, Asma Essat, Mathieu Angin, Mathilde Ghislain, Kathleen Gärtner, Nicolas Huot
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2016, 12 (8), pp.11-7. ⟨10.1371/journal.ppat.1005774⟩
PLoS Pathogens, 2016, 12 (8), pp.11-7. ⟨10.1371/journal.ppat.1005774⟩
PLoS pathogens, 12(8). Public Library of Science
PLoS Pathogens, Public Library of Science, 2016, 12 (8), pp.11-7. 〈10.1371/journal.ppat.1005774〉
PLoS Pathogens, Vol 12, Iss 8, p e1005774 (2016)
PLoS Pathogens, Public Library of Science, 2016, 12 (8), pp.11-7. ⟨10.1371/journal.ppat.1005774⟩
PLoS Pathogens, 2016, 12 (8), pp.11-7. ⟨10.1371/journal.ppat.1005774⟩
PLoS pathogens, 12(8). Public Library of Science
PLoS Pathogens, Public Library of Science, 2016, 12 (8), pp.11-7. 〈10.1371/journal.ppat.1005774〉
PLoS Pathogens, Vol 12, Iss 8, p e1005774 (2016)
Elevated blood CXCL10/IP-10 levels during primary HIV-1 infection (PHI) were described as an independent marker of rapid disease onset, more robust than peak viremia or CD4 cell nadir. IP-10 enhances the recruitment of CXCR3+ cells, which include maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d221ea09b6e52dacc2f650583c0dca3d
http://europepmc.org/articles/PMC4980058
http://europepmc.org/articles/PMC4980058
Autor:
Brigitte Boeser-Nunnink, Hanneke Schuitemaker, Marit J. van Gils, Tom L.G.M. van den Kerkhof, Judith A. Burger, Rogier W. Sanders
Publikováno v:
AIDS (London, England), 30(14), 2179-2184. Lippincott Williams and Wilkins
Objective(s) The glycan shield of the HIV-1 envelope glycoprotein complex (Env), in particular the glycan at position 332 in gp120, is frequently targeted by broadly neutralizing antibodies (bNAbs) isolated from HIV-1-infected individuals. We investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3227ab06b3ac8258ffa0cc40f09404
https://pubmed.ncbi.nlm.nih.gov/27258397
https://pubmed.ncbi.nlm.nih.gov/27258397
Autor:
Dennis R. Burton, Brigitte Boeser-Nunnink, Neeltje A. Kootstra, Marit J. van Gils, Steven W. de Taeye, Hanneke Schuitemaker, Rogier W. Sanders, Tom L.G.M. van den Kerkhof
Publikováno v:
Retrovirology
Retrovirology, 13(1). BioMed Central
Retrovirology, 13(1). BioMed Central
Background Current HIV-1 immunogens are unable to induce antibodies that can neutralize a broad range of HIV-1 (broadly neutralizing antibodies; bNAbs). However, such antibodies are elicited in 10–30 % of HIV-1 infected individuals, and the co-evol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21bf91ee3003e305647a3bcb19141119
https://doi.org/10.1186/s12977-016-0279-4
https://doi.org/10.1186/s12977-016-0279-4