Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brigitte Bocchi"'
Autor:
Michel Hubert Capron, Jean Fiet, Martine Muffat-Joly, Sabine Kenouch, Nicolette Farman, Maxime Lamarre-Cliche, Brigitte Bocchi, Michel Azizi, Jean Pierre Bonvalet, Gilles Morineau
Publikováno v:
Hypertension. 43:803-808
The enzyme 11-β hydroxysteroid dehydrogenase type 2 plays a major role in blood pressure regulation. It metabolizes glucocorticoid hormones into derivatives with low affinity for the mineralocorticoid receptor, preventing its permanent occupancy by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d01148e44ac2ff579cca2501a1b5c6a
https://doi.org/10.1161/01.hyp.0000121362.64182.ad
https://doi.org/10.1161/01.hyp.0000121362.64182.ad
Autor:
Marie-Edith Rafestin-Oblin, Brigitte Bocchi, Anny Souque, Alain Vandewalle, Jérôme Fagart, G.M. Pinon
Publikováno v:
Endocrinology. 144:528-533
A gain of function mutation resulting in the substitution of leucine for serine at codon 810 (S810L) in the human mineralocorticoid receptor (MR) is responsible for early-onset hypertension that is exacerbated in pregnancy. All steroids, including pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d996fc4b1af8706a580cd131ae366c
https://doi.org/10.1210/en.2002-220708
https://doi.org/10.1210/en.2002-220708
Autor:
Nicolette Farman, Marie-Edith Rafestin-Oblin, Michel Fay, Françoise Cluzeaud, Brigitte Bocchi, Jérôme Fagart
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 84:239-244
The mineralocorticoid receptor (MR) binds aldosterone, but also glucocorticoid hormones (corticosterone in rodents, cortisol in humans), which largely prevail in the plasma. To prevent permanent and maximal occupancy of MR by glucocorticoid hormones
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04b691db6edd13e83c80add66be30275
https://doi.org/10.1016/s0960-0760(03)00036-0
https://doi.org/10.1016/s0960-0760(03)00036-0
Autor:
Nicolette Farman, Brigitte Bocchi
Publikováno v:
Kidney International. 57(4):1364-1369
Mineralocorticoid selectivity: Molecular and cellular aspects. Aldosterone acts in mineralocorticoid-sensitive cells by binding to the mineralocorticoid receptor (MR). Because the MR displays similar affinity for aldosterone and glucocorticoid hormon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e737eb5ff58a72d323e6bcac5d2408
Autor:
Brigitte Escoubet, Stephane Cailmail, Claude Delcayre, Antoine Ouvrard-Pascaud, Vanessa Delage, Frederic Jaisser, Brigitte Bocchi, Ahmed T. Beggah, Michel Peuchmaur, Nicolette Farman, Stefania Puttini
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2002, 99, pp.7160-5. ⟨10.1073/pnas.102673599⟩
ResearcherID
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2002, 99, pp.7160-5. ⟨10.1073/pnas.102673599⟩
ResearcherID
Cardiac failure is a common feature in the evolution of cardiac disease. Among the determinants of cardiac failure, the renin–angiotensin–aldosterone system has a central role, and antagonism of the mineralocorticoid receptor (MR) has been propos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd2385f3d67e0d25b81ac3aa945bdf93
https://www.hal.inserm.fr/inserm-00128553
https://www.hal.inserm.fr/inserm-00128553
