Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Brigitte Blöchl-Daum"'
Autor:
Brigitte Blöchl-Daum
Publikováno v:
Wiener Medizinische Wochenschrift. 156:494-497
Die Unterscheidung zwischen Innovator und "Me-too"-Praparaten in einer therapeutischen Klasse ist klinisch meist nicht relevant. Das Konzept eines Klasseneffekts, der Analogpraparate untereinander austauschbar macht, ist nur fur wenige Substanzklasse
Autor:
Hans-Georg Eichler, G. T. Dorner, Brigitte Blöchl-Daum, Michael Wolzt, Guenther G. Steger, Gabriela Kornek, Kurt Kletter, H. Pehamberger, P. James, Helene Breiteneder, Markus Müller
Publikováno v:
European Journal of Clinical Investigation. 27:836-839
The aim of this study was to evaluate the renal protective effect of linotroban, a thromboxane A2 receptor antagonist, in 25 patients with malignant tumours scheduled for cisplatin therapy. Cisplatin was administered 1 h after the start of a 24-h con
Autor:
Robert M. Mader, Hugo Rainer, Markus Müller, Brigitte Blöchl-Daum, S. Lang, G. Zanaschka, R. Eglmeier, W. Millesi, Hans-Georg Eichler
Publikováno v:
Scopus-Elsevier
The aim of this study was to quantify first-pass uptake of methotrexate into tumour and healthy tissue after intra-arterial (i.a.) injection in patients with head and neck cancers. Twenty-one patients were studied ; during surgery, a bolus injection
Autor:
Hans-Georg Eichler, V Meisinger, A. Fassolt, Hubert Pehamberger, M Müller, Brigitte Blöchl-Daum
Publikováno v:
British Journal of Cancer
Clinical anti-tumour efficacy of anti-cancer drugs is a function of dose intensity, i.e. the concentration--time profile in tumour tissue. Hence, information on drug concentration profiles in tumours is of critical importance but appropriate methods
Autor:
Christine Kurz, Paul-Alexander Kyrle, Brigitte Monitzer, Oswald Wagner, Hubert Pehamberger, Markus Müller, Hans-Georg Eichler, Brigitte Blöchl-Daum
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:418-424
Purpose Thromboxane A2 (TxA2) is implicated in the pathogenesis of various forms of drug-induced renal damage. Based on previous functional studies, we postulated that cis-dichlorodiammineplatinum (cisplatin) induces intrarenal TxA2 synthesis. To tes
Autor:
Terrence F. Blaschke, Hans-Georg Eichler, Brian B. Hoffman, Gary A. Ford, Brigitte Blöchl-Daum, Fredric B. Kraemer
Publikováno v:
Clinical Science. 82:163-168
1. Diabetic autonomic neuropathy causes loss of sympathetic cardiovascular control and is associated with increased vascular sensitivity to catecholamines. Supersensitivity to catecholamines could be due to either a postsynaptic increase in vascular
Autor:
A. Korn, Brigitte Blöchl-Daum, Kornelia Böhler, Sanja Schuller-Petrovic, Hans-Georg Eichler, Michael Wolzt
Publikováno v:
Clinical Pharmacology and Therapeutics. 49:49-52
Responsiveness of superficial hand veins to local infusions of noradrenaline was compared in patients with primary varicose veins and in healthy volunteers by use of the dorsal hand vein technique. Patients with varicose veins required significantly
Autor:
Manfred Götz, Brigitte Blöchl-Daum, Irmgard Eichler, A. Korn, Hans-Georg Eichler, Michael Wolzt
Publikováno v:
Journal of Allergy and Clinical Immunology. 86:714-725
Impaired function of the adrenergic-receptor system has been postulated to contribute to the pathogenesis of bronchial asthma. Using the dorsal hand-vein compliance technique, we compared the changes in diameter of superficial hand veins in response
Autor:
Brigitte, Blöchl-Daum
Publikováno v:
Wiener medizinische Wochenschrift (1946). 156(17-18)
A distinction between "Breakthrough-drug" and "Me-too-drug" within one therapeutic class of medication is usually not clinically relevant. The concept of a class effect, which would mean, that one "Me-too drug" could be substituted with another one f
Autor:
Barbara Schneider, Paul A. Kyrle, Brunhilde Wagner, Hans-Georg Eichler, Brigitte Brenner, Klaus Lechner, Slobodan Gasic, Brigitte Blöchl-Daum
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology. 346
We have studied in 12 healthy volunteers the effects of two angiotensin-converting enzyme (ACE) inhibitors, captopril and cilazapril, on vascular and platelet prostaglandin metabolism, in a double-blind, placebo-controlled, randomized cross-over stud