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pro vyhledávání: '"Brigitte A. Askonas"'
Autor:
Brigitte A. Askonas
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 77:611-622
Recent work concerned with protein biosynthesis in mammalian systems is reviewed. Antibody protein was chosen as an example of a specific protein and its formation and secretion was studied in slices of lymphoid and reticuloendothelial organs of immu
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 51:267-289
César Milstein was a scientist of the greatest distinction who made seminal contributions to our knowledge and understanding of antibodies. He advanced our knowledge of their structure, their expression, the generation of antibody diversity and the
Autor:
Brigitte A. Askonas, James G. Howard
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 43:237-251
Niels Jerne was unquestionably one of the most distinguished immunologists of the present century. Although a relatively late starter—he was approaching 40 before he seriously embarked on a research career—he soon made a major impact that altered
Autor:
Brigitte A. Askonas
Publikováno v:
Biographical Memoirs of Fellows of the Royal Society. 36:273-300
John Herbert Humphrey was an outstanding immunologist and a most remarkable person in every way. His broad knowledge of the immune system was unparalleled, and there were few aspects of immunology that his own experiments did not touch on. John was a
Autor:
Brigitte A. Askonas
Publikováno v:
Annual Review of Immunology. 8:1-22
Publikováno v:
International immunology. 8(3)
We have previously demonstrated that intranasal (i.n.) administration of an immunodominant peptide (p1-111-139) derived from the house dust mite (HDM) allergen Der p 1 inhibits antigen-specific CD4+ T cell responses in H-2b mice. Here we report that
Publikováno v:
International Immunology
Several CD4+ Th1 clones specific for Influenza haemagglutinln or nucleoproteln were transferred into syngeneic mice after Intranasal Influenza infection to examine whether they accelerate viral clearance in vivo similarly to CD8+ cytotoxlc T cells. W
Autor:
Brigitte A. Askonas, Robert G. Webster
Publikováno v:
European Journal of Immunology. 10:151-156
The target antigens recognized by the cross-reactive population of cytotoxic T cells on A/USSR/90/77 (H 1N 1) influenza virus-infected cells was studied with monoclonal antibodies to the H-2k antigen and viral hemagglutinin. The cytotoxic killing of