Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Brigitte, van Zundert"'
Autor:
Pablo Martínez, Mónica Silva, Sebastián Abarzúa, María Florencia Tevy, Enrique Jaimovich, Martha Constantine-Paton, Fernando J. Bustos, Brigitte van Zundert
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-19 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motoneurons (MNs), and despite progress, there is no effective treatment. A large body of evidence shows that astrocytes expressing ALS-lin
Externí odkaz:
https://doaj.org/article/d3d643b2145c4f048ce0d7b5e781c070
Autor:
Ramón Pérez-Núñez, Alejandro Chamorro, María Fernanda González, Pamela Contreras, Rocío Artigas, Alejandro H. Corvalán, Brigitte van Zundert, Christopher Reyes, Pablo R. Moya, Ana María Avalos, Pascal Schneider, Andrew F. G. Quest, Lisette Leyton
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-19 (2023)
Abstract Background In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can
Externí odkaz:
https://doaj.org/article/8f88a252b77145c0982c107e62d40b7f
Autor:
Fabiola Rojas, Rodrigo Aguilar, Sandra Almeida, Elsa Fritz, Daniela Corvalán, Estibaliz Ampuero, Sebastián Abarzúa, Polett Garcés, Armando Amaro, Iván Diaz, Cristian Arredondo, Nicole Cortes, Mario Sanchez, Constanza Mercado, Lorena Varela-Nallar, Fen-Biao Gao, Martin Montecino, Brigitte van Zundert
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Astrocytes play a critical role in the maintenance of a healthy central nervous system and astrocyte dysfunction has been implicated in various neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FT
Externí odkaz:
https://doaj.org/article/70b04753b9844b6f898175dad9993d01
Autor:
Alexis Martinez, Cristian M. Lamaizon, Cristian Valls, Fabien Llambi, Nancy Leal, Patrick Fitzgerald, Cliff Guy, Marcin M. Kamiński, Nibaldo C. Inestrosa, Brigitte van Zundert, Gonzalo I. Cancino, Andrés E. Dulcey, Silvana Zanlungo, Juan J. Marugan, Claudio Hetz, Douglas R. Green, Alejandra R. Alvarez
Publikováno v:
Antioxidants, Vol 12, Iss 11, p 2007 (2023)
The endoplasmic reticulum is a subcellular organelle key in the control of synthesis, folding, and sorting of proteins. Under endoplasmic reticulum stress, an adaptative unfolded protein response is activated; however, if this activation is prolonged
Externí odkaz:
https://doaj.org/article/52442aebd7684326868078bfe18e45e8
Autor:
Miguel V. Guerra, Matías I. Cáceres, Andrea Herrera-Soto, Sebastián B. Arredondo, Manuel Varas-Godoy, Brigitte van Zundert, Lorena Varela-Nallar
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2022)
In the dentate gyrus of the adult hippocampus new neurons are generated from neural precursor cells through different stages including proliferation and differentiation of neural progenitor cells and maturation of newborn neurons. These stages are co
Externí odkaz:
https://doaj.org/article/62de9ae5e0b1424193784b28f2923b97
Autor:
Raúl Lagos-Cabré, Alvaro Alvarez, Milene Kong, Francesca Burgos-Bravo, Areli Cárdenas, Edgardo Rojas-Mancilla, Ramón Pérez-Nuñez, Rodrigo Herrera-Molina, Fabiola Rojas, Pascal Schneider, Mario Herrera-Marschitz, Andrew F. G. Quest, Brigitte van Zundert, Lisette Leyton
Publikováno v:
Journal of Neuroinflammation, Vol 14, Iss 1, Pp 1-13 (2017)
Abstract Background Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging αVβ3 Integrin and Syndecan-4. Primary astrocytes express low levels of these recepto
Externí odkaz:
https://doaj.org/article/098ca1bbe8ac4c6987fb170d55625e4a
Autor:
Brigitte van Zundert, Martin Montecino
Publikováno v:
International journal of molecular sciences. 23(20)
Healthy brain functioning in mammals requires a continuous fine-tuning of gene expression. Accumulating evidence over the last three decades demonstrates that epigenetic mechanisms and dynamic changes in chromatin organization are critical components
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351c9962b776ba8ddc508c3dae0df15d
https://pubmed.ncbi.nlm.nih.gov/36292933
https://pubmed.ncbi.nlm.nih.gov/36292933
Autor:
David Gonzalez, Osvaldo Contreras, Daniela L Rebolledo, Juan Pablo Espinoza, Brigitte van Zundert, Enrique Brandan
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177649 (2017)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle
Externí odkaz:
https://doaj.org/article/088715e82b534461b31e1a377b7de6d6
Autor:
Ramón, Pérez-Núñez, Alejandro, Chamorro, María Fernanda, González, Pamela, Contreras, Rocío, Artigas, Alejandro H, Corvalán, Brigitte, van Zundert, Christopher, Reyes, Pablo R, Moya, Ana María, Avalos, Pascal, Schneider, Andrew F G, Quest, Lisette, Leyton
Publikováno v:
Journal of neuroinflammation. 20(1)
In response to brain injury or inflammation, astrocytes undergo hypertrophy, proliferate, and migrate to the damaged zone. These changes, collectively known as "astrogliosis", initially protect the brain; however, astrogliosis can also cause neuronal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f238e9b7bee55d722c75438a63f631c9
https://pubmed.ncbi.nlm.nih.gov/36609298
https://pubmed.ncbi.nlm.nih.gov/36609298
Autor:
Estibaliz Ampuero, Andrea Herrera-Soto, Fernando J. Bustos, Patricia V. Jorquera, Lorena Varela-Nallar, Brigitte van Zundert, Muriel D. Mardones
Publikováno v:
Journal of Chemical Neuroanatomy. 98:117-123
In the adult hippocampus new neurons are generated in the dentate gyrus from neural progenitor cells. Adult-born neurons integrate into the hippocampal circuitry and contribute to hippocampal function. PSD95 is a major postsynaptic scaffold protein t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb3769e491b9b7675b64442d2b21b6e
https://doi.org/10.1016/j.jchemneu.2019.04.009
https://doi.org/10.1016/j.jchemneu.2019.04.009