Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Brigitte, Pelzmann"'
Autor:
Sonja Langthaler, Christian Zumpf, Theresa Rienmüller, Niroj Shrestha, Julia Fuchs, Rui Zhou, Brigitte Pelzmann, Klaus Zorn-Pauly, Eleonore Fröhlich, Seth H. Weinberg, Christian Baumgartner
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
IntroductionAdvances in molecular targeting of ion channels may open up new avenues for therapeutic approaches in cancer based on the cells’ bioelectric properties. In addition to in-vitro or in-vivo models, in silico models can provide deeper insi
Externí odkaz:
https://doaj.org/article/3111c1c30d0e4ced9bbeeb33ac65fe04
Autor:
Brigitte Pelzmann, Ahmed Hatab, Susanne Scheruebel, Sonja Langthaler, Theresa Rienmueller, Armin Sokolowski, Astrid Gorischek, Dieter Platzer, Klaus Zorn-Pauly, Stephan W. Jahn, Thomas Bauernhofer, Wolfgang Schreibmayer
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
A search in the GDC Data Portal revealed 304 documented somatic mutations of the KCNJ3 gene in primary tumors (out of 10.202 cases). Most affected tumor types were carcinomas from uterus, skin and lung, while breast cancer exerted the lowest number o
Externí odkaz:
https://doaj.org/article/25e751d727e649c9b262bb838d06b3f1
Autor:
Sonja Langthaler, Theresa Rienmüller, Susanne Scheruebel, Brigitte Pelzmann, Niroj Shrestha, Klaus Zorn-Pauly, Wolfgang Schreibmayer, Andrew Koff, Christian Baumgartner
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009091 (2021)
Lung cancer is still a leading cause of death worldwide. In recent years, knowledge has been obtained of the mechanisms modulating ion channel kinetics and thus of cell bioelectric properties, which is promising for oncological biomarkers and targets
Externí odkaz:
https://doaj.org/article/7c9b1d683b294f9d9f84e22b31257110
Autor:
Chintan N. Koyani, Susanne Scheruebel, Ge Jin, Ewald Kolesnik, Klaus Zorn-Pauly, Heinrich Mächler, Gerald Hoefler, Dirk von Lewinski, Frank R. Heinzel, Brigitte Pelzmann, Ernst Malle
Publikováno v:
Antioxidants, Vol 11, Iss 1, p 25 (2021)
Neutrophil-derived myeloperoxidase (MPO) and its potent oxidant, hypochlorous acid (HOCl), gained attention as important oxidative mediators in cardiac damage and dysfunction. As cardiomyocytes generate low-density lipoprotein (LDL)-like particles, w
Externí odkaz:
https://doaj.org/article/ee18e49989614a159991e8ff2ff00f62
Autor:
Helmut Bischof, Markus Rehberg, Sarah Stryeck, Katharina Artinger, Emrah Eroglu, Markus Waldeck-Weiermair, Benjamin Gottschalk, Rene Rost, Andras T. Deak, Tobias Niedrist, Nemanja Vujic, Hanna Lindermuth, Ruth Prassl, Brigitte Pelzmann, Klaus Groschner, Dagmar Kratky, Kathrin Eller, Alexander R. Rosenkranz, Tobias Madl, Nikolaus Plesnila, Wolfgang F. Graier, Roland Malli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
K+ plays an important role in physiology and disease, but the lack of high specificity K+ sensors limits our understanding of its spatiotemporal dynamics. Here the authors develop genetically-encoded FRET-based probes able to quantify K+ concentratio
Externí odkaz:
https://doaj.org/article/3f0690a062df4c16ae8ab8e09d354078
Autor:
Emrah Eroglu, Benjamin Gottschalk, Suphachai Charoensin, Sandra Blass, Helmut Bischof, Rene Rost, Corina T. Madreiter-Sokolowski, Brigitte Pelzmann, Eva Bernhart, Wolfgang Sattler, Seth Hallström, Tadeusz Malinski, Markus Waldeck-Weiermair, Wolfgang F. Graier, Roland Malli
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nitric oxide is a volatile free radical second messenger with a large number of biological effects. Here Eroglu et al. develop genetically encoded fluorescent biosensors for nitric oxide and use them to visualise subcellular nitric oxide dynamics in
Externí odkaz:
https://doaj.org/article/02df81f9cf6b4bff83bc4f0ad4df3c56
Autor:
Chintan N. Koyani, Christopher Trummer, Niroj Shrestha, Susanne Scheruebel, Benjamin Bourgeois, Ioanna Plastira, Sandra Kickmaier, Harald Sourij, Peter P. Rainer, Tobias Madl, Wolfgang Sattler, Brigitte Pelzmann, Ernst Malle, Dirk von Lewinski
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Some oral anti-hyperglycemic drugs, including gliptins that inhibit dipeptidyl peptidase 4 (DPP4), have been linked to the increased risk of heart failure (HF) in type-2 diabetic patients. While the cardiovascular safety trial, TECOS, revealed no lin
Externí odkaz:
https://doaj.org/article/5c059d136840483897cf25c2ae10e440
Autor:
Helmut Ahammer, Susanne Scheruebel, Robert Arnold, Michael Mayrhofer-Reinhartshuber, Petra Lang, Ádám Dolgos, Brigitte Pelzmann, Klaus Zorn-Pauly
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Beat to beat variability of cardiac tissue or isolated cells is frequently investigated by determining time intervals from electrode measurements in order to compute scale dependent or scale independent parameters. In this study, we utilize high-spee
Externí odkaz:
https://doaj.org/article/bf557f2843bd486e88bcf267ae9e83d9
Publikováno v:
Banach Center Publications. 124:11-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::196c599f86c625558958238a679cd3f6
https://doi.org/10.4064/bc124-1
https://doi.org/10.4064/bc124-1
Autor:
Wolfgang Schreibmayer, Ruth Prassl, Stefanie Stanzer, Katja Ester, Sonja Langthaler, Nassim Ghaffari-Tabrizi-Wizsy, Simin Rezania, Andreas Prokesch, Helmut Ahammer, Dieter Platzer, Susanne Scheruebel, Brigitte Pelzmann, Klaus Zorn-Pauly, Gebhard Schratter, Trevor DeVaney, Thomas Bauernhofer, Kurt Schmidt, Astrid Gorischek, Stephan W Jahn
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Scientific Reports
Scientific Reports
Excessive expression of subunit 1 of GIRK1 in ER+ breast tumors is associated with reduced survival times and increased lymph node metastasis in patients. To investigate possible tumor-initiating properties, benign MCF10A and malign MCF7 mammary epit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0d014586551eca02950fc98bfd08de
http://link.springer.com/article/10.1038/s41598-019-55683-w
http://link.springer.com/article/10.1038/s41598-019-55683-w