Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Brigitte, Hartmann"'
Autor:
Akiko Hatakeyama, Yuliia Shymko, Brigitte Hartmann, Romain Retureau, Claude Nogues, Marco Pasi, Malcolm Buckle
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0267382 (2022)
Structural fluctuations of nucleosomes modulate the access to internal DNA in eukaryotic cells; clearly characterisation of this fundamental process is crucial to understanding gene regulation. Here we apply PhAST (Photochemical Analysis of Structura
Externí odkaz:
https://doaj.org/article/172fee7f1d27433e83c6fa122c09314d
Autor:
Julien Hardy, Dingli Dai, Anissia Ait Saada, Ana Teixeira-Silva, Louise Dupoiron, Fatemeh Mojallali, Karine Fréon, Francoise Ochsenbein, Brigitte Hartmann, Sarah Lambert
Publikováno v:
PLoS Genetics, Vol 15, Iss 10, p e1008441 (2019)
Replication stress poses a serious threat to genome stability. Recombination-Dependent-Replication (RDR) promotes DNA synthesis resumption from arrested forks. Despite the identification of chromatin restoration pathways after DNA repair, crosstalk c
Externí odkaz:
https://doaj.org/article/965f560ec0c24687a5e588ffa77f36cc
Autor:
Akli Ben Imeddourene, Ahmad Elbahnsi, Marc Guéroult, Christophe Oguey, Nicolas Foloppe, Brigitte Hartmann
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 12, p e1004631 (2015)
The accurate prediction of the structure and dynamics of DNA remains a major challenge in computational biology due to the dearth of precise experimental information on DNA free in solution and limitations in the DNA force-fields underpinning the sim
Externí odkaz:
https://doaj.org/article/6976a8e8185c48eab154ac6ca98fdbf7
Autor:
Hatice Duran, Brigitte Hartmann, Henning Eickmeier, Ulrich Scheler, Markus Haase, Salim Ok, Martin Steinhart
Publikováno v:
Journal of Polymer Science Part B: Polymer Physics. 57:1402-1408
Publikováno v:
Journal of Structural Biology
Journal of Structural Biology, Elsevier, 2020, 211, pp.107511-. ⟨10.1016/j.jsb.2020.107511⟩
Journal of Structural Biology, Elsevier, 2020, 211, pp.107511-. ⟨10.1016/j.jsb.2020.107511⟩
Most of eukaryotic cellular DNA is packed in nucleosome core particles (NCPs), in which the DNA (DNANCP) is wrapped around histones. The influence of this organization on the intrinsic local dynamics of DNA is largely unknown, in particular because c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516bd2c73a84cc1f2a3f3da4947c1af4
https://hal.archives-ouvertes.fr/hal-03490872
https://hal.archives-ouvertes.fr/hal-03490872
Nucleosome assembly and disassembly play a central role in the regulation of gene expression. Here we use PhAST (Photochemical Analysis of Structural Transitions) to monitor at the base pair level, structural alterations induced all along DNA upon hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ec8edd63d16376d0bcfa3d6914c9ad6
https://doi.org/10.1101/2020.04.01.020263
https://doi.org/10.1101/2020.04.01.020263
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e41704 (2012)
This study investigates the effect of Mg(2+) bound to the DNA major groove on DNA structure and dynamics. The analysis of a comprehensive dataset of B-DNA crystallographic structures shows that divalent cations are preferentially located in the DNA m
Externí odkaz:
https://doaj.org/article/28feb7c243df4725a7be925bfb4c2059
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15931 (2010)
BACKGROUND: The B-DNA major and minor groove dimensions are crucial for DNA-protein interactions. It has long been thought that the groove dimensions depend on the DNA sequence, however this relationship has remained elusive. Here, our aim is to eluc
Externí odkaz:
https://doaj.org/article/fba765d71fb2481595eb79f19bd678aa
Publikováno v:
PLoS Computational Biology, Vol 6, Iss 11, p e1001000 (2010)
DNase I requires Ca²+ and Mg²+ for hydrolyzing double-stranded DNA. However, the number and the location of DNase I ion-binding sites remain unclear, as well as the role of these counter-ions. Using molecular dynamics simulations, we show that bovi
Externí odkaz:
https://doaj.org/article/a90dc937c278452bbdd6f09e509cf4d6
Autor:
Sarah Lambert, Dingli Dai, Karine Fréon, Brigitte Hartmann, Fatemeh Mojallali, Ana Teixeira-Silva, Françoise Ochsenbein, Julien Hardy, Louise Dupoiron, Anissia Ait Saada
Publikováno v:
PLoS Genetics
PLoS Genetics, 2019, 15 (10), pp.e1008441. ⟨10.1371/journal.pgen.1008441⟩
PLoS Genetics, Public Library of Science, 2019, 15 (10), pp.e1008441. ⟨10.1371/journal.pgen.1008441⟩
PLoS Genetics, Vol 15, Iss 10, p e1008441 (2019)
PLoS Genetics, 2019, 15 (10), pp.e1008441. ⟨10.1371/journal.pgen.1008441⟩
PLoS Genetics, Public Library of Science, 2019, 15 (10), pp.e1008441. ⟨10.1371/journal.pgen.1008441⟩
PLoS Genetics, Vol 15, Iss 10, p e1008441 (2019)
Replication stress poses a serious threat to genome stability. Recombination-Dependent-Replication (RDR) promotes DNA synthesis resumption from arrested forks. Despite the identification of chromatin restoration pathways after DNA repair, crosstalk c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d927a2bb6d4f768ab33187597ea2d88
https://hal.science/hal-02331102/file/pgen.1008441.pdf
https://hal.science/hal-02331102/file/pgen.1008441.pdf