Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brigitta Mester"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140432 (2015)
Ex vivo generated monocyte-derived dendritic cell (moDC)-vaccines have long been touted as promising immunotherapeutic agents for cancer treatment, although the response rate generally remains low. The reasons for this are still unclear and confounde
Externí odkaz:
https://doaj.org/article/78b562a0dba34df492a4689fa781ab17
Autor:
Nathaniel Dasyam, Katrina J. Sharples, Catherine Barrow, Ying Huang, Evelyn Bauer, Brigitta Mester, Catherine E. Wood, Astrid Authier-Hall, Marina Dzhelali, Tess Ostapowicz, Rajiv Kumar, Jessica Lowe, Alice Maxwell, Olivia K. Burn, Geoffrey M. Williams, Sarah E. Carley, Graham Caygill, Jeremy Jones, Susanna T. S. Chan, Victoria A. Hinder, Jerome Macapagal, Monica McCusker, Robert Weinkove, Margaret A. Brimble, Gavin F. Painter, Michael P. Findlay, P. Rod Dunbar, Olivier Gasser, Ian F. Hermans
Publikováno v:
Cancer Immunology, Immunotherapy.
Aim We have previously reported that polyfunctional T cell responses can be induced to the cancer testis antigen NY-ESO-1 in melanoma patients injected with mature autologous monocyte-derived dendritic cells (DCs) loaded with long NY-ESO-1-derived pe
Autor:
Nathaniel Dasyam, Tess Ostapowicz, Chris Frampton, Robert Weinkove, Giulia Giunti, Evelyn Bauer, Bethany Andrews, David Ritchie, Catherine M. Bollard, Peng Li, Travis Perera, Ian F. Hermans, Philip George, Brigitta Mester
Publikováno v:
BMJ Open
IntroductionAutologous T-cells transduced to express a chimeric antigen receptor (CAR) directed against CD19 elicit high response rates in relapsed or refractory (r/r) B-cell non-Hodgkin lymphoma (B-NHL). However, r/r B-NHL remissions are durable in
Autor:
Michael Findlay, Robert Weinkove, Marina Dzhelali, Ian F. Hermans, Graham Caygill, Geoffrey M. Williams, Margaret A. Brimble, Victoria Hinder, Olivier Gasser, Monica McCusker, Gavin F. Painter, Jerome Macapagal, Catherine Wood, P. Rod Dunbar, Catherine Barrow, Brigitta Mester, Evelyn Bauer, Jeremy D. Jones, Katrina Sharples, Colin M. Hayman
Publikováno v:
Cancer Immunology, Immunotherapy. 67:285-298
Vaccines that elicit targeted tumor antigen-specific T-cell responses have the potential to be used as adjuvant therapy in patients with high risk of relapse. However, the responses induced by vaccines in cancer patients have generally been disappoin
Autor:
Margaret A. Brimble, Ian F. Hermans, Brigitta Mester, C. Barrow, Gavin F. Painter, Olivier Gasser, R. Dunbar, Nathaniel Dasyam, M. McCusker, Robert Weinkove, K. Sharples, E. Bauer
Publikováno v:
Cytotherapy. 23:S98
Autor:
Katrina Sharples, Michael Findlay, Brigitta Mester, Marina Dzhelali, Olivier Gasser, Martin K. Hunn, Lindsay R. Ancelet, David Hamilton, Evelyn Bauer, Ian F. Hermans, Catherine Wood
Publikováno v:
Journal of Neuro-Oncology. 121:319-329
There is no standard treatment for recurrent glioblastoma multiforme (GBM). Retreatment with temozolomide (TMZ) is one treatment option. We reasoned this could be more effective if combined with a vaccine that preferentially targeted TMZ-resistant ce
Autor:
Brigitta Mester, Philip George, Q. Le, Robert Weinkove, Nathaniel Dasyam, Giulia Giunti, Ian F. Hermans, Peng Li
Publikováno v:
Hematological Oncology. 37:517-517
Autor:
Kenneth P. McNatty, Robert B. Gilchrist, Janet L. Pitman, Brigitta Mester, Adrian H Bibby, Jennifer L. Juengel, C Joy McIntosh, Lesley J. Ritter
Publikováno v:
Reproduction, fertility, and development. 27(5)
Bone morphogenetic protein 15 (BMP15) is a key intraovarian growth factor regulating mammalian fertility, yet expression and localisation of different BMP15 protein forms within ovarian follicles around the time of the preovulatory LH surge remains u
Autor:
Michael Beaumont, Jennifer L. Juengel, Brian P. Thomson, Brigitta Mester, Lisa J Haydon, Douglas C. Eckery
Publikováno v:
Reproduction (Cambridge, England). 140(2)
IGFs are known to be key regulators of ovarian follicular growth in eutherian mammals, but little is known regarding their role in marsupials. To better understand the potential role of IGFs in the regulation of follicular growth in marsupials, expre
Expression of CD1a and Type-1 Polarization Are Dissociated in Human Monocyte-Derived Dendritic Cells
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140432 (2015)
PLoS ONE
PLoS ONE
Ex vivo generated monocyte-derived dendritic cell (moDC)-vaccines have long been touted as promising immunotherapeutic agents for cancer treatment, although the response rate generally remains low. The reasons for this are still unclear and confounde