Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Brigitta M, Brinkman"'
Autor:
Ken Vercammen, Jens-Michael Schröder, Brigitta M. Brinkman, Jeroen Raes, Jurgen Del Favero, Peter Vandenabeele, Falk Hildebrand, Wim Declercq, Malgorzata Kubica, Dirk Goossens, Pierre Cornelis
Publikováno v:
Experimental dermatology
Caspase-14, an important proteinase involved in filaggrin catabolism, is mainly active in terminally differentiating keratinocytes, where it is required for the generation of skin natural moisturizing factors (NMFs). Consequently, caspase-14 deficien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b73d56f02bd5fdce9e735b2089b56ae
https://doi.org/10.1111/exd.12458
https://doi.org/10.1111/exd.12458
Autor:
Peter Vandenabeele, Agnieszka Kaczmarek, Liesbeth Heyndrickx, Dmitri V. Krysko, Brigitta M. Brinkman
Publikováno v:
The Journal of Pathology. 226:598-608
Intestinal mucositis is a serious complication of cancer chemotherapy and radiotherapy; it frequently compromises treatment and dramatically reduces the quality of life of patients. Different approaches to limit the damage to the intestine during ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::860ded161bd6cdb2c7499a57fb25deb3
https://doi.org/10.1002/path.3009
https://doi.org/10.1002/path.3009
Publikováno v:
FEMS Microbiology Reviews
FEMS MICROBIOLOGY REVIEWS
FEMS MICROBIOLOGY REVIEWS
Targeted manipulation of the gut flora is increasingly being recognized as a means to improve human health. Yet, the temporal dynamics and intra- and interindividual heterogeneity of the microbiome represent experimental limitations, especially in hu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00dfc34b18c7a287d9071b393e6f4c11
https://hdl.handle.net/20.500.14017/3943dd0a-c493-4562-bfa7-da27aec184c0
https://hdl.handle.net/20.500.14017/3943dd0a-c493-4562-bfa7-da27aec184c0
Autor:
Pieter Hindryckx, Martine De Vos, Claude Cuvelier, Peter Vandenabeele, Yves-Paul Vandewynckel, Lindsey Devisscher, Brigitta M. Brinkman, Lien Van den Bossche, Roosmarijn E. Vandenbroucke, Debby Laukens, Claude Libert
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 94(12)
Ulcerative colitis (UC) is characterized by increased epithelial cell death and subsequent breakdown of the intestinal epithelial barrier, which perpetuates chronic intestinal inflammation. Since fecal bile acid dysmetabolism is associated with UC an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::126bfac9375e28e18786d4f786fc6e4d
https://pubmed.ncbi.nlm.nih.gov/25310532
https://pubmed.ncbi.nlm.nih.gov/25310532
Autor:
Rene B. Ayiseh, Anne A. M. J. Becker, Geert Huys, Peter Vandenabeele, Falk Hildebrand, Jeroen Raes, Brigitta M. Brinkman
Publikováno v:
Inflammatory bowel diseases. 19(12)
Caspase-deficient mice and wild-type (WT) mice show significant differences in their gut microbiota composition. These differences coincide with the observation that caspase-3-deficient mice carrying a natural caspase-11 mutation (Casp3/11(-/-)) are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d6e01456fe537203e4d8493adf2351
https://pubmed.ncbi.nlm.nih.gov/24105395
https://pubmed.ncbi.nlm.nih.gov/24105395
Autor:
Brigitta M. Brinkman, Malgorzata Kubica, Falk Hildebrand, D Goosens, Wim Declercq, Jeroen Raes, J Del Favero, Peter Vandenabeele
Publikováno v:
Cell Death and Disease; Vol 2
Cell Death and Disease
Cell Death & Disease
Cell Death and Disease
Cell Death & Disease
Caspases are aspartate-specific cysteine proteases that have an essential role in apoptosis and inflammation, and contribute to the maintenance of homeostasis in the intestine. These facts, together with the knowledge that caspases are implicated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ab4a7e1c7fa36a734ad4146a5f37be
https://hdl.handle.net/20.500.14017/ba0b179d-02a4-49f9-bb07-afef44b96c12
https://hdl.handle.net/20.500.14017/ba0b179d-02a4-49f9-bb07-afef44b96c12
Autor:
Agnieszka, Kaczmarek, Brigitta M, Brinkman, Liesbeth, Heyndrickx, Peter, Vandenabeele, Dmitri V, Krysko
Publikováno v:
The Journal of pathology. 226(4)
Intestinal mucositis is a serious complication of cancer chemotherapy and radiotherapy; it frequently compromises treatment and dramatically reduces the quality of life of patients. Different approaches to limit the damage to the intestine during ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a122fcc9009ca3c89bf58fc99855fb65
https://pubmed.ncbi.nlm.nih.gov/21960132
https://pubmed.ncbi.nlm.nih.gov/21960132
Autor:
Harald Peeters, Sara Bogaert, Peter Vandenabeele, Brigitta M. Brinkman, Dirk Elewaut, Pieter Hindryckx, Martine De Vos, Peggy Jacques, Liesbeth Ferdinande, Kim Olievier, Debby Laukens
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 185(10)
Hydroxylase inhibitors stabilize hypoxia-inducible factor-1 (HIF-1), which has barrier-protective activity in the gut. Because the inflammatory cytokine TNF-α contributes to inflammatory bowel disease in part by compromising intestinal epithelial ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123f50c49040c685aaf3992c9c2a7113
https://pubmed.ncbi.nlm.nih.gov/20943999
https://pubmed.ncbi.nlm.nih.gov/20943999
Autor:
Falk Hildebrand, Roberto Garcia Yunta, Bénédicte Cauwe, Brigitta M. Brinkman, Adrian Liston, Peter Vandenabeele, Jeroen Raes, Thi Loan Anh Nguyen
Publikováno v:
GENOME BIOLOGY
Genome Biology
Genome Biology
BACKGROUND: Murine models are a crucial component of gut microbiome research. Unfortunately, a multitude of genetic backgrounds and experimental setups, together with inter-individual variation complicates cross-study comparisons and a global underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b5b04ac1f9a2dc4bdcfbf12e179e45
https://doi.org/10.1186/gb-2013-14-1-r4
https://doi.org/10.1186/gb-2013-14-1-r4
Autor:
Martine De Vos, Harald Peeters, Peter Vandenabeele, Pieter Hindryckx, Debby Laukens, Peggy Jacques, Liesbeth Ferdinande, Brigitta M. Brinkman, Dirk Elewaut
Publikováno v:
Gastroenterology. 138:S-411
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d82a8101e84e56c1df47746ae77f592
https://doi.org/10.1016/s0016-5085(10)61894-x
https://doi.org/10.1016/s0016-5085(10)61894-x