Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Brigita, Vigante"'
Autor:
Karolis Leitonas, Brigita Vigante, Dmytro Volyniuk, Audrius Bucinskas, Pavels Dimitrijevs, Sindija Lapcinska, Pavel Arsenyan, Juozas Vidas Grazulevicius
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 1867-1880 (2023)
The pyridine-3,5-dicarbonitrile moiety has gained significant attention in the field of materials chemistry, particularly in the development of heavy-metal-free pure organic light-emitting diodes (OLEDs). Extensive research on organic compounds exhib
Externí odkaz:
https://doaj.org/article/c41dca9c3ce64667a7b343bb7cddd070
Autor:
Karina Spunde, Brigita Vigante, Unda Nelda Dubova, Anda Sipola, Irena Timofejeva, Anna Zajakina, Juris Jansons, Aiva Plotniece, Karlis Pajuste, Arkadij Sobolev, Ruslan Muhamadejev, Kristaps Jaudzems, Gunars Duburs, Tatjana Kozlovska
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 773 (2022)
Capsid assembly modulators (CAMs) have emerged as a promising class of antiviral agents. We studied the effects of twenty-one newly designed and synthesized CAMs including heteroaryldihydropyrimidine compounds (HAPs), their analogs and standard compo
Externí odkaz:
https://doaj.org/article/5b764d434c0343ef92d6e057be5efee9
Autor:
Egils Bisenieks, Brigita Vigante, Ramona Petrovska, Baiba Turovska, Ruslan Muhamadejev, Vitalijs Soloduns, Astrida Velena, Karlis Pajuste, Luciano Saso, Janis Klovins, Gunars Duburs, Ilona Mandrika
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 987 (2021)
The paradigm of ligand-receptor interactions postulated as “one compound—one target” has been evolving; a multi-target, pleiotropic approach is now considered to be realistic. Novel series of 1,4,5,6,7,8-hexahydro-5-oxoquinolines, pyranopyrimid
Externí odkaz:
https://doaj.org/article/8caf4940419f481f9c13e6506e351cd8
Autor:
Nadiia V. Pikun, Arkadij Sobolev, Aiva Plotniece, Martins Rucins, Brigita Vigante, Marina Petrova, Ruslan Muhamadejev, Karlis Pajuste, Yuriy G. Shermolovich
Publikováno v:
Molecules, Vol 25, Iss 14, p 3143 (2020)
New fluorinated 3,6-dihydropyridines were obtained by the electrophilic fluorination of 1,2-dihydropyridines with Selectfluor®. These 3-fluoro-3,6-dihydropyridines were easily converted to corresponding pyridines by the elimination of hydrogen fluor
Externí odkaz:
https://doaj.org/article/019eef6c88ad4adc9bb17e376cba1e80
Autor:
Brigita Vigante, Martins Rucins, Aiva Plotniece, Karlis Pajuste, Iveta Luntena, Brigita Cekavicus, Egils Bisenieks, Rufus Smits, Gunars Duburs, Arkadij Sobolev
Publikováno v:
Molecules, Vol 20, Iss 11, Pp 20341-20354 (2015)
The ethoxycarbonylmethyl esters of 1,4-dihydropyridines were directly converted into carbamoylmethyl esters in the presence of 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD) in good to excellent yields under mild conditions. The use of TBD is crucial for
Externí odkaz:
https://doaj.org/article/0eee7127df4b4de8bf1e72700caf66ed
Autor:
Levani Skhirtladze, Pavel Arsenyan, Dmytro Volyniuk, Karolis Leitonas, Sergey Belyakov, Brigita Vigante, Viktorija Andruleviciene, Juozas V. Grazulevicius
Publikováno v:
Journal of Materials Chemistry C. 9:3928-3938
A procedure for post-functionalization by 3,6-di-tert-butyl-carbazole or 3,7-dibromophenothiazine of dicyanopyridines was developed. Pyridine rings in new pyridines exist in a twist-conformation in the solid state. Green and orange thermally activate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da9f688f7a7ad897b8d9d2bc2e50da2
https://doi.org/10.1039/d0tc05745b
https://doi.org/10.1039/d0tc05745b
Autor:
Brigita Cekavicus, Ruslan Muhamadejev, Gunars Duburs, Edvards Liepinsh, Aiva Plotniece, Brigita Vigante, Marina Petrova
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 8041-8052 (2011)
The diastereotopy of the methylene protons at positions 2 and 6 in 1,4-dihydropiridine derivatives with various substituents has been investigated. NMR spectroscopy and quantum chemistry calculations show that the CH···O intramolecular hydrogen bo
Externí odkaz:
https://doaj.org/article/fec2fab5841f459bbe9296fdf9d8f165
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 11, Pp 379-381 (2014)
The asymmetric unit of the title compound, C10H14N2O3, contains two independent molecules with similar conformations. In the both molecules, the cyclohexene rings adopt the same envelope conformation with the flap C atoms lying 0.658 (3) and 0.668 (3
Externí odkaz:
https://doaj.org/article/a6fbf29481bc416ea5027198e2c36dde
Autor:
Gunita Apsite, Irena Timofejeva, Aleksandra Vezane, Brigita Vigante, Martins Rucins, Arkadij Sobolev, Mara Plotniece, Karlis Pajuste, Tatjana Kozlovska, Aiva Plotniece
Publikováno v:
Molecules, Vol 23, Iss 7, p 1540 (2018)
New amphiphilic 1,4-DHP derivative C12-Man-Q with remoted cationic moieties at positions 2 and 6 was synthesised to study DNA delivery activity. The results were compared with data obtained for cationic 1,4-DHP derivative D19, which is known to be th
Externí odkaz:
https://doaj.org/article/611c777d0f414362a47fcbfe447e4b6d
Screening of SIRT6 inhibitors and activators: A novel activator has an impact on breast cancer cells
Autor:
Jonna Tenhunen, Tomáš Kučera, Marjo Huovinen, Jenni Küblbeck, Egils Bisenieks, Brigita Vigante, Zaiga Ogle, Gunars Duburs, Martin Doležal, Ruin Moaddel, Maija Lahtela-Kakkonen, Minna Rahnasto-Rilla
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss, Pp 111452-(2021)
Sirtuin 6 (SIRT6), a member of sirtuin family (SIRT1-7), regulates a variety of cellular processes involved in aging, metabolism, and cancer. Dysregulation of SIRT6 is widely observed in different breast cancer subtypes; however, the role and functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58f314754949e72d53cdc51b73a478e6
http://www.sciencedirect.com/science/article/pii/S0753332221002377
http://www.sciencedirect.com/science/article/pii/S0753332221002377