Maternal SARS-CoV-2 impacts fetal placental macrophage programs and placenta-derived microglial models of neurodevelopment.

Autor: Shook LL; Vincent Center for Reproductive Biology, Massachusetts General Hospital, 55 Fruit Street, Thier Research Building, 903B, Boston, MA, 02114, USA.; Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA., Batorsky RE; Data Intensive Studies Center, Tufts University, Boston, MA, USA., De Guzman RM; Vincent Center for Reproductive Biology, Massachusetts General Hospital, 55 Fruit Street, Thier Research Building, 903B, Boston, MA, 02114, USA.; Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., McCrea LT; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Brigida SM; Vincent Center for Reproductive Biology, Massachusetts General Hospital, 55 Fruit Street, Thier Research Building, 903B, Boston, MA, 02114, USA., Horng JE; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Sheridan SD; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Kholod O; Thayer School of Engineering and Program, Dartmouth College, Hanover, NH, USA., Cook AM; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Li JZ; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Slonim DK; Department of Computer Science, Tufts University, Medford, MA, USA., Goods BA; Thayer School of Engineering and Program, Dartmouth College, Hanover, NH, USA.; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH, USA., Perlis RH; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Edlow AG; Vincent Center for Reproductive Biology, Massachusetts General Hospital, 55 Fruit Street, Thier Research Building, 903B, Boston, MA, 02114, USA. aedlow@mgh.harvard.edu.; Department of Obstetrics, Gynecology and Reproductive Biology, Harvard Medical School, Boston, MA, USA. aedlow@mgh.harvard.edu.

Publikováno v: Journal of neuroinflammation [J Neuroinflammation] 2024 Jun 25; Vol. 21 (1), pp. 163. Date of Electronic Publication: 2024 Jun 25.