Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Briggs Morrison"'
Autor:
Joyson J. Karakunnel, Nam Bui, Latha Palaniappan, Keith T. Schmidt, Kenneth W. Mahaffey, Briggs Morrison, William D. Figg, Shivaani Kummar
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Abstract Background With the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in healthy volunteers (HVs). The primary goal of these studies is to investigate t
Externí odkaz:
https://doaj.org/article/82b0410fbfbb4a57994b7c8206a1d584
Autor:
Briggs Morrison, Latha Palaniappan, Joyson J. Karakunnel, Keith T. Schmidt, Kenneth W. Mahaffey, William D. Figg, Nam Bui, Shivaani Kummar
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-15 (2018)
Background With the exception of genotoxic oncology drugs, first-in-human, Phase 1 clinical studies of investigational drugs have traditionally been conducted in healthy volunteers (HVs). The primary goal of these studies is to investigate the pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e00f04337420996e9155e305961a35e
http://europepmc.org/articles/PMC6278009
http://europepmc.org/articles/PMC6278009
Autor:
Stephen M, Hahn, Eric J, Bernhard, William, Regine, Mohammed, Mohiuddin, Daniel G, Haller, James P, Stevenson, Debbie, Smith, Barnali, Pramanik, Joel, Tepper, Thomas F, DeLaney, Krystina D, Kiel, Briggs, Morrison, Paul, Deutsch, Ruth J, Muschel, W Gillies, McKenna
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 8(5)
Preclinical data have demonstrated that farnesyltransferaseinhibitors (FTIs) are radiation sensitizers in selected cell lines. The objective of this Phase I trial was to determine the maximally tolerated dose of the FTI L-778,123 in combination with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20d76143b9f27e2e237c27133b2a58eb
https://pubmed.ncbi.nlm.nih.gov/12006520
https://pubmed.ncbi.nlm.nih.gov/12006520