Repetitive, mild traumatic brain injury results in a progressive white matter pathology, cognitive deterioration, and a transient gut microbiota dysbiosis.

Autor: Angoa-Pérez M; Research and Development Service, John D. Dingell VA Medical Center, Detroit, MI, USA. maperez@med.wayne.edu.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA. maperez@med.wayne.edu., Zagorac B; Research and Development Service, John D. Dingell VA Medical Center, Detroit, MI, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA., Anneken JH; Research and Development Service, John D. Dingell VA Medical Center, Detroit, MI, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA., Briggs DI; Research and Development Service, John D. Dingell VA Medical Center, Detroit, MI, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA.; Stanford Behavioral and Functional Neuroscience Laboratory, Department of Neurosurgery, Stanford University Medical School, Stanford, CA, USA., Winters AD; Department of Biochemistry, Microbiology and Immunology, Wayne State University School of Medicine, Detroit, MI, USA., Greenberg JM; Department of Biochemistry, Microbiology and Immunology, Wayne State University School of Medicine, Detroit, MI, USA., Ahmad M; Department of Biochemistry, Microbiology and Immunology, Wayne State University School of Medicine, Detroit, MI, USA., Theis KR; Department of Biochemistry, Microbiology and Immunology, Wayne State University School of Medicine, Detroit, MI, USA.; Perinatal Research Initiative in Maternal, Perinatal and Child Health, Wayne State University School of Medicine, Detroit, MI, USA., Kuhn DM; Research and Development Service, John D. Dingell VA Medical Center, Detroit, MI, USA.; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, USA.

Publikováno v: Scientific reports [Sci Rep] 2020 Jun 02; Vol. 10 (1), pp. 8949. Date of Electronic Publication: 2020 Jun 02.

Role of Endoplasmic Reticulum Stress in Learning and Memory Impairment and Alzheimer's Disease-Like Neuropathology in the PS19 and APP ^Swe Mouse Models of Tauopathy and Amyloidosis.

Autor: Briggs DI; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593., Defensor E; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593., Memar Ardestani P; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593., Yi B; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593., Halpain M; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593., Seabrook G; California Innovation Center, Johnson & Johnson, Menlo Park, CA 94025-5232., Shamloo M; Department of Neurosurgery, Stanford University School of Medicine, Palo Alto, CA 94304-5593.

Publikováno v: ENeuro [eNeuro] 2017 Jul 14; Vol. 4 (4). Date of Electronic Publication: 2017 Jul 14 (Print Publication: 2017).

Prolonged Repetitive Head Trauma Induces a Singular Chronic Traumatic Encephalopathy-Like Pathology in White Matter Despite Transient Behavioral Abnormalities.

Autor: Briggs DI; Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan. Electronic address: dbriggs@med.wayne.edu., Angoa-Pérez M; Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan., Kuhn DM; Research and Development Service, John D. Dingell VA Medical Center, Detroit, Michigan; Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan.

Publikováno v: The American journal of pathology [Am J Pathol] 2016 Nov; Vol. 186 (11), pp. 2869-2886. Date of Electronic Publication: 2016 Sep 20.

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

Autor: Briggs DI; Department of Physiology (D.I.B., S.H.L., Q.W., R.S., A.R., M.B.L., H.A.C., H.C.P., Z.B.A.), Monash University, Clayton, Victoria 3800, Australia; Traditional Chinese Medicine Department (Q.W.), Peking Union Medical College Hospital, Beijing, China 100730; Department of Physiology (J.B., A.J.H.), Bosch Institute, The University of Sydney, New South Wales 2006, Australia; and Department of Animal Physiology (A.T.), Faculty of Biology, Philipps University, Marburg, D-35043 Marburg, Germany., Lockie SH, Benzler J, Wu Q, Stark R, Reichenbach A, Hoy AJ, Lemus MB, Coleman HA, Parkington HC, Tups A, Andrews ZB

Publikováno v: Endocrinology [Endocrinology] 2014 Jul; Vol. 155 (7), pp. 2411-22. Date of Electronic Publication: 2014 Apr 17.

Marble burying and nestlet shredding as tests of repetitive, compulsive-like behaviors in mice.

Autor: Angoa-Pérez M; Research and Development Service, John D. Dingell VA Medical Center and Department of Psychiatry & Behavioral Neurosciences, Wayne State University School of Medicine., Kane MJ, Briggs DI, Francescutti DM, Kuhn DM

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2013 Dec 24 (82), pp. 50978. Date of Electronic Publication: 2013 Dec 24.