Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Brigette Tippin Davis"'
Autor:
Suzette Farber-Katz, Vickie Hsuan, Sitao Wu, Tyler Landrith, Huy Vuong, Dong Xu, Bing Li, Jayne Hoo, Stephanie Lam, Sarah Nashed, Deborah Toppmeyer, Phillip Gray, Ginger Haynes, Hsiao-Mei Lu, Aaron Elliott, Brigette Tippin Davis, Rachid Karam
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Clinical genetic testing for hereditary breast and ovarian cancer (HBOC) is becoming widespread. However, the interpretation of variants of unknown significance (VUS) in HBOC genes, such as the clinically actionable genes BRCA1 and BRCA2, remain a ch
Externí odkaz:
https://doaj.org/article/ac330a471ac74523a1d861cc1c74206b
Autor:
Tyler Landrith, Bing Li, Ashley A. Cass, Blair R. Conner, Holly LaDuca, Danielle B. McKenna, Kara N. Maxwell, Susan Domchek, Nichole A. Morman, Christopher Heinlen, Deborah Wham, Cathryn Koptiuch, Jennie Vagher, Ragene Rivera, Ann Bunnell, Gayle Patel, Jennifer L. Geurts, Morgan M. Depas, Shraddha Gaonkar, Sara Pirzadeh-Miller, Rebekah Krukenberg, Meredith Seidel, Robert Pilarski, Meagan Farmer, Khateriaa Pyrtel, Kara Milliron, John Lee, Elizabeth Hoodfar, Deepika Nathan, Amanda C. Ganzak, Sitao Wu, Huy Vuong, Dong Xu, Aarani Arulmoli, Melissa Parra, Lily Hoang, Bhuvan Molparia, Michele Fennessy, Susanne Fox, Sinead Charpentier, Julia Burdette, Tina Pesaran, Jessica Profato, Brandon Smith, Ginger Haynes, Emily Dalton, Joy Rae-Radecki Crandall, Ruth Baxter, Hsiao-Mei Lu, Brigette Tippin-Davis, Aaron Elliott, Elizabeth Chao, Rachid Karam
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-9 (2020)
Abstract Germline variants in tumor suppressor genes (TSGs) can result in RNA mis-splicing and predisposition to cancer. However, identification of variants that impact splicing remains a challenge, contributing to a substantial proportion of patient
Externí odkaz:
https://doaj.org/article/50f2e0c212b24359a87e5f0fd59980ac
Autor:
Jill S. Dolinsky, Brigette Tippin Davis, David E. Goldgar, Tina Pesaran, Jenna Lilyquist, Jie Na, Holly LaDuca, Amal Yussuf, Nancy Niguidula, Elizabeth C. Chao, Chunling Hu, Hermela Shimelis, Steven N. Hart, Siddhartha Yadav, Fergus J. Couch, Kun Y. Lee, Stephanie Gutierrez, Eric C. Polley
Publikováno v:
JNCI Journal of the National Cancer Institute
To evaluate the racial and ethnic differences in prevalence of germline pathogenic variants (PVs) and the effect of race and ethnicity on breast cancer (BC) risk among carriers, results of multigene testing of 77 900 women with BC (non-Hispanic White
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f878a957b7b1952845553924295cf4
https://doi.org/10.1093/jnci/djaa167
https://doi.org/10.1093/jnci/djaa167
Autor:
Shuwei Li, Robert Hoiness, Siqun Lilly Zheng, Brian T. Helfand, Mary Helen Black, Jun Wei, Jefferey Chen, Jianfeng Xu, Kathleen E. Wiley, Stephanie Gutierrez, Brigette Tippin-Davis, Min-Tzu Lo, Hsiao Mei Lu, William B. Isaacs, Holly LaDuca, Zhuqing Shi, Marta Gielzak
Publikováno v:
The Prostate
Background Genome‐wide association studies have identified over 100 single‐nucleotide polymorphisms (SNPs) associated with prostate cancer (PrCa), and polygenic risk scores (PRS) based on their combined genotypes have been developed for risk stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeae415641ec22d8b744367012fae5dd
https://doi.org/10.1002/pros.24058
https://doi.org/10.1002/pros.24058
Autor:
Tina Pesaran, Elizabeth C. Chao, Jessica Profato, Holly LaDuca, Chia Ling Gau, Carolyn Horton, David E. Goldgar, Siddhartha Yadav, Jill S. Dolinsky, Jie Na, Lily Hoang, Melissa Pronold, Fergus J. Couch, Eric C. Polley, Chunling Hu, Brigette Tippin Davis, Laura Panos Smith, Stephanie Gutierrez, Amal Yussuf, Kelly Fulk, Steven N. Hart
Publikováno v:
Genetics in Medicine
Purpose Despite the rapid uptake of multigene panel testing (MGPT) for hereditary cancer predisposition, there is limited guidance surrounding indications for testing and genes to include. Methods To inform the clinical approach to hereditary cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b95de2404409940db6205b678a73e8a
https://doi.org/10.1038/s41436-019-0633-8
https://doi.org/10.1038/s41436-019-0633-8
Autor:
Gayle Patel, Morgan M Depas, Lily Hoang, Rob Pilarski, Brigette Tippin Davis, Elizabeth Hoodfar, Cara S. Dresbold, Olivia L. Tan, Meagan Farmer, Danielle Menashe, Samantha Stachowiak, Deborah Wham, Khateriaa Pyrtel, Sandra B. Jenkinson, Tiffani Demarco, Sara Pirzadeh-Miller, Elizabeth C. Chao, Danielle McKenna, Catherine Koptiuch, Jessica Profato, Rebekah C. Krukenberg, Jennifer L. Geurts, John G. Lee, Shraddha Gaonkar, Jen Moore, Nichole A. Morman, Danielle Dondanville, Deepika Nathan, Rachid Karam, Meredith Seidel, Holly LaDuca, Amal Yussuf, Kara J. Milliron, Carolyn Horton, Jill S. Dolinsky, Diane Samad, Cassie Garcia
Publikováno v:
Cancer Research. 80:P6-08
BACKGROUND: Germline genetic testing is routinely incorporated into clinical care for breast cancer patients to inform management decisions and reduce risk for developing subsequent cancers. While the diagnostic yield of cancer genetic testing has in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a50932ad25e8a5992a3fd2a38eb880ba
https://doi.org/10.1158/1538-7445.sabcs19-p6-08-08
https://doi.org/10.1158/1538-7445.sabcs19-p6-08-08
Autor:
Phillip Gray, Beth Souders, Swati Shah, Chia Ling Gau, Carla Mason, Megan L. Landsverk, Negar Ghahramani, Brittany Dougall, Brigette Tippin-Davis, Kory Jasperson, Stephanie Gutierrez, Melissa R.F. Truelson, Kelly Fulk, Elizabeth C. Chao, Jessica Profato, Daniel Chen, Melissa Pronold, Hsiao Mei Lu, Mary Helen Black, Holly LaDuca, Monalyn Umali Salvador
Publikováno v:
Journal of Clinical Oncology
PURPOSE The current diagnostic testing algorithm for Lynch syndrome (LS) is complex and often involves multiple follow-up germline and somatic tests. We aimed to describe the results of paired tumor/germline testing performed on a large cohort of pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd3843d83c1490e469a734034178320b
https://doi.org/10.1200/jco.18.00696
https://doi.org/10.1200/jco.18.00696
Autor:
Meagan Farmer, Brandon Smith, Kara N. Maxwell, Brigette Tippin-Davis, Julia Burdette, Danielle McKenna, Ashley A. Cass, Sinead Charpentier, Sitao Wu, Emily Dalton, Melissa Parra, Susanne Fox, Aaron Elliott, Holly LaDuca, Cathryn Koptiuch, Susan M. Domchek, Elizabeth Hoodfar, Robert Pilarski, Dong Xu, Khateriaa Pyrtel, Kara J. Milliron, Michele Fennessy, Gayle Patel, Lily Hoang, Morgan M Depas, Tina Pesaran, Rachid Karam, Meredith Seidel, Ann Bunnell, Huy Gia Vuong, Deborah Wham, Bing Li, Ragene Rivera, Jennie Vagher, Nichole A. Morman, Aarani Arulmoli, Sara Pirzadeh-Miller, Hsiao-Mei Lu, Jessica Profato, Joy Rae-Radecki Crandall, Elizabeth C. Chao, Ruth Baxter, Shraddha Gaonkar, Ginger Haynes, Amanda Ganzak, Deepika Nathan, Jennifer L. Geurts, Blair R. Conner, Tyler Landrith, Rebekah Krukenberg, John J. Lee, Christopher Heinlen, Bhuvan Molparia
Publikováno v:
npj Precision Oncology, Vol 4, Iss 1, Pp 1-9 (2020)
NPJ Precision Oncology
NPJ Precision Oncology
Germline variants in tumor suppressor genes (TSGs) can result in RNA mis-splicing and predisposition to cancer. However, identification of variants that impact splicing remains a challenge, contributing to a substantial proportion of patients with su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d16807d808110f22b027a699b83d981
https://doi.org/10.1038/s41698-020-0109-y
https://doi.org/10.1038/s41698-020-0109-y
Autor:
Kate Krempely, Stephany Tandy-Connor, Holly LaDuca, Brigette Tippin Davis, Stephanie Gutierrez, Jenna Guiltinan, Patrick Reineke, Phillip Gray
Publikováno v:
Genetics in Medicine
Purpose There is increasing demand from the public for direct-to-consumer (DTC) genetic tests, and the US Food and Drug Administration limits the type of health-related claims DTC tests can market. Some DTC companies provide raw genotyping data to cu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88377214ed8f13df0475ec2ced55dcf
http://europepmc.org/articles/PMC6301953
http://europepmc.org/articles/PMC6301953
Autor:
Blair R. Conner, Suzette Farber-Katz, Rachid Karam, Aaron Elliott, Jill S. Dolinsky, Patrick Reineke, Marcy E. Richardson, Elizabeth C. Chao, Deborah Toppmeyer, Sarah Nashed, Ginger Haynes, John J. Lee, Brigette Tippin Davis, Kyle Allen, Tina Pesaran, Stephanie Gutierrez, Amal Yussuf, Holly LaDuca, Debra L. Collins, Samantha Culver, Lily Hoang, Kelly McGoldrick, Huma Q. Rana, Kate Krempely, Heather Zimmermann
Publikováno v:
JAMA network open. 2(10)
Importance Performing DNA genetic testing (DGT) for hereditary cancer genes is now a well-accepted clinical practice; however, the interpretation of DNA variation remains a challenge for laboratories and clinicians. Adding RNA genetic testing (RGT) e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1255e7ea8e8731fbb1469d2b0d9634f
https://pubmed.ncbi.nlm.nih.gov/31642931
https://pubmed.ncbi.nlm.nih.gov/31642931