Contractile cell apoptosis regulates airway smooth muscle remodeling in asthma

Autor: Plaza, Alfonso Torrego, Martínez-Rivera C, B. Lema‐Costa, López-Viña A, David Ramos-Barbón, Qutayba Hamid, Óscar Amor-Carro, James G. Martin, Núñez-Naveira L, Bazús-González T, Carmen Montero-Martínez, Brienza Ns, Francisco-Javier González-Barcala, Berger P, R. Fraga‐Iriso

RationaleInvestigations on the mechanisms of airway smooth muscle remodeling, a prominent asthma feature contributing to its clinical manifestations and severity, have largely focused on its hyperplastic growth. Conversely, limited data and virtually

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cab39e0349cdaf4c671f616039fa0d97
https://doi.org/10.1101/2021.02.08.21251269

T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodeling.

Autor: Zhou, Muyang, Sun, Rui, Jang, Joyce, Martin, James G.

Publikováno v: American Journal of Physiology: Lung Cellular & Molecular Physiology; Sep2024, Vol. 327 Issue 3, pL382-L394, 13p

[Development of a murine model of airway inflammation and remodeling in experimental asthma].

Autor: Fraga-Iriso R; Unidad de Investigación Respiratoria, Servicio de Neumología, Complejo Hospitalario Universitario, Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, España., Núñez-Naveira L, Brienza NS, Centeno-Cortés A, López-Peláez E, Verea H, Ramos-Barbón D

Publikováno v: Archivos de bronconeumologia [Arch Bronconeumol] 2009 Sep; Vol. 45 (9), pp. 422-8. Date of Electronic Publication: 2009 May 21.

Bronchom assuages airway hyperresponsiveness in house dust mite-induced mouse model of allergic asthma and moderates goblet cell metaplasia, sub-epithelial fibrosis along with changes in Th2 cytokines and chemokines.

Autor: Balkrishna, Acharya, Sinha, Sandeep, Karumuri, Shadrakbabu, Maity, Madhulina, Dev, Rishabh, Varshney, Anurag

Publikováno v: Frontiers in Immunology; 2024, p01-21, 21p

Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle.

Autor: Jackson, Devine¹ (AUTHOR), Walum, Joshua¹ (AUTHOR), Banerjee, Priyanka² (AUTHOR), Lewis, Brandon W.¹ (AUTHOR), Prakash, Y. S.^3,4 (AUTHOR), Sathish, Venkatachalem² (AUTHOR), Xu, Zhaohui^5,6 (AUTHOR), Britt Jr, Rodney D.^1,6 (AUTHOR) Rodney.Britt@nationwidechildrens.org, Britt, Rodney D Jr^6,7 (AUTHOR)

Publikováno v: Respiratory Research. 5/16/2022, Vol. 23 Issue 1, p1-17. 17p.