Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Brienne A, McKenzie"'
Autor:
Brienne A. McKenzie, Jason P. Fernandes, Matthew A. L. Doan, Laura M. Schmitt, William G. Branton, Christopher Power
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-25 (2020)
Abstract Background Pyroptosis is a type of proinflammatory regulated cell death (RCD) in which caspase-1 proteolytically cleaves gasdermin D (GSDMD) to yield a cytotoxic pore-forming protein. Recent studies have suggested that additional cell death
Externí odkaz:
https://doaj.org/article/691b8686e7984ecbb15161b3bf767202
Autor:
Peter A. Forsyth, V. Wee Yong, Grant McFadden, Karlyne M. Reilly, Xueqing Lun, Brienne A. McKenzie, Franz J. Zemp
Legend for Supplementary Figures S1-S10.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3938a3bc99d0bb1f401f90777b83a618
https://doi.org/10.1158/0008-5472.22402796.v1
https://doi.org/10.1158/0008-5472.22402796.v1
Autor:
Peter A. Forsyth, V. Wee Yong, Grant McFadden, Karlyne M. Reilly, Xueqing Lun, Brienne A. McKenzie, Franz J. Zemp
Immunophenotyping of the K1492 glioma microenvironment in response to sterile injury (S1); Immunophenotyping of the K1492 glioma microenvironment after Myxoma virus treatment (S2); Virus infected areas of K1492 tumours are accompanied by polymorphonu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bd93d6ec666111f7e94786632baf71
https://doi.org/10.1158/0008-5472.22402793
https://doi.org/10.1158/0008-5472.22402793
Autor:
Andrej Roczkowsky, Matthew A.L. Doan, Brittyne A. Hlavay, Manmeet K. Mamik, William G. Branton, Brienne A. McKenzie, Leina B. Saito, Laura Schmitt, Gary Eitzen, Francesca Di Cara, Melinda Wuest, Frank Wuest, Richard Rachubinski, Christopher Power
Publikováno v:
J Neurosci
Multiple sclerosis (MS) is a progressive and inflammatory demyelinating disease of the CNS. Peroxisomes perform critical functions that contribute to CNS homeostasis. We investigated peroxisome injury and mitigating effects of peroxisome-restorative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a355fee13403530349070484eb295fef
https://europepmc.org/articles/PMC9480879/
https://europepmc.org/articles/PMC9480879/
Publikováno v:
Trends in Neurosciences. 43:55-73
Pyroptosis ('fiery death') is an inflammatory type of regulated cell death (RCD), which occurs downstream of inflammasome activation. Pyroptosis is mediated directly by the recently identified family of pore-forming proteins known as gasdermins, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1a5ebd93ec1eb93ab500311cda6bad
https://doi.org/10.1016/j.tins.2019.11.005
https://doi.org/10.1016/j.tins.2019.11.005
Autor:
Franz J Zemp, Brienne A McKenzie, Xueqing Lun, Lori Maxwell, Karlyne M Reilly, Grant McFadden, V Wee Yong, Peter A Forsyth
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65801 (2013)
Despite promising preclinical studies, oncolytic viral therapy for malignant gliomas has resulted in variable, but underwhelming results in clinical evaluations. Of concern are the low levels of tumour infection and viral replication within the tumou
Externí odkaz:
https://doaj.org/article/405f255494594f22b92ce95accb05091
Autor:
Jason P Fernandes, Matthew A. L. Doan, Laura M. Schmitt, William G. Branton, Brienne A. McKenzie, Christopher Power
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-25 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Pyroptosis is a type of proinflammatory regulated cell death (RCD) in which caspase-1 proteolytically cleaves gasdermin D (GSDMD) to yield a cytotoxic pore-forming protein. Recent studies have suggested that additional cell death pathways
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d7bfc36300b88086f30eeb232c75b5
https://doi.org/10.1186/s12974-020-01902-5
https://doi.org/10.1186/s12974-020-01902-5
Autor:
William G. Branton, Glen B. Baker, Christopher Power, Farshid Noorbakhsh, Ninad Mehta, Jian-Qiang Lu, Brienne A. McKenzie, Roobina Boghozian, Leina B. Saito
Publikováno v:
Glia. 65:1590-1606
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::652f3682db2505fb8b531ee45389dd9f
https://doi.org/10.1002/glia.23179
https://doi.org/10.1002/glia.23179
Autor:
Patricia A. Chen, F K H van Landeghem, William G. Branton, Gaurav Shrivastava, Jason P Fernandes, Brienne A. McKenzie, Blaise M. Wheatley, Erin F Balcom, Kenneth C. Petruk, Christopher Power
Publikováno v:
Journal of neuro-oncology. 144(2)
Inflammation is a key aspect of glioblastoma multiforme (GBM) although it remains unclear how it contributes to GBM pathogenesis. Inflammasomes are intracellular multi-protein complexes that are involved in innate immunity and are activated by cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2f51fdebddaa9c59437a7d3affc821
https://pubmed.ncbi.nlm.nih.gov/31280432
https://pubmed.ncbi.nlm.nih.gov/31280432
Autor:
Christopher Power, Wing Fuk Chan, Eugene L. Asahchop, Brienne A. McKenzie, Yu Zhu, William G. Branton, Éric A. Cohen, Manmeet K. Mamik
Publikováno v:
The Journal of Neuroscience. 36:10683-10695
HIV-1 infection of the brain causes the neurodegenerative syndrome HIV-associated neurocognitive disorders (HAND), for which there is no specific treatment. Herein, we investigated the actions of insulin usingex vivoandin vivomodels of HAND. Increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2b19966ed2ec11d35dae6e2c2741360
https://doi.org/10.1523/jneurosci.1287-16.2016
https://doi.org/10.1523/jneurosci.1287-16.2016