Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Bridie J. Goggins"'
Autor:
Jemma R Mayall, Jay C Horvat, Niamh E Mangan, Anne Chevalier, Huw McCarthy, Daniel Hampsey, Chantal Donovan, Alexandra C Brown, Antony Y Matthews, Nicole A de Weerd, Eveline D de Geus, Malcolm R Starkey, Richard Y Kim, Katie Daly, Bridie J Goggins, Simon Keely, Steven Maltby, Rennay Baldwin, Paul S Foster, Michael J Boyle, Pradeep S Tanwar, Nicholas D Huntington, Paul J Hertzog, Philip M Hansbro
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 2, Pp 267-293 (2024)
Abstract The uterus is a unique mucosal site where immune responses are balanced to be permissive of a fetus, yet protective against infections. Regulation of natural killer (NK) cell responses in the uterus during infection is critical, yet no studi
Externí odkaz:
https://doaj.org/article/27c077dad3a5489b8adb434699dbf324
Autor:
Leon A. Sokulsky, Simon Keely, Philip G. Board, Paul S. Foster, Ming Yang, Simonne Sherwin, Gerard E. Kaiko, Fiona Eyers, Bridie J. Goggins
Publikováno v:
Clinical & Experimental Allergy. 50:609-624
BACKGROUND Glutathione S-transferases omega class 1 (GSTO1-1) is a unique member of the GST family regulating cellular redox metabolism and innate immunity through the promotion of LPS/TLR4/NLRP3 signalling in macrophages. House dust mite (HDM) trigg
Autor:
Jessica K. Bruce, Grace L. Burns, Wai Sinn Soh, Prema M. Nair, Simonne Sherwin, KeNing Fan, Laura R. Dowling, Bridie J. Goggins, Natasha Koloski, Michael Potter, Steven Bollipo, Robert Foster, Lay T. Gan, Martin Veysey, Dana J. Philpott, Stephen E. Girardin, Gerald Holtmann, Gerard E. Kaiko, Marjorie M. Walker, Nicholas J. Talley, Simon Keely
Publikováno v:
Brain, behavior, and immunity. 101
Functional dyspepsia (FD) affects up to 15% of the population and is characterised by recurring upper gastrointestinal (GI) symptoms occurring in the absence of clinically identifiable pathology. Psychological stress is a key factor associated with t
Autor:
Gang Liu, Kyra Minahan, Jay C. Horvat, Bridie J. Goggins, Wai S. Soh, Simonne Sherwin, Simon Keely, Marjorie M. Walker, Jennifer Pryor, Andrea Mathe, Jessica Bruce, Darryl A. Knight
Intestinal epithelia are critical for maintaining gastrointestinal homeostasis. Epithelial barrier injury, causing inflammation and vascular damage, results in inflammatory hypoxia, and thus, healing occurs in an oxygen-restricted environment. The tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758cddf00035a6ce8d82b38fbcc41dcb
https://hdl.handle.net/10453/154451
https://hdl.handle.net/10453/154451
Autor:
Hock L. Tay, Paul S. Foster, Jay C. Horvat, Bridie J. Goggins, Steven Maltby, Philip M. Hansbro, Ellen Marks, Marjorie M. Walker, Sean W. Mateer, Michael Fricker, Kyra Minahan, Andrea Mathe, Grace Burns, Jessica Bruce, Richard Kim, Robert C. Callister, Gang Liu, Simon Keely
Publikováno v:
The American Journal of Pathology. 188:1625-1639
© 2018 American Society for Investigative Pathology Inflammatory bowel disease (IBD) is associated with several immune-mediated extraintestinal manifestations. More than half of all IBD patients have some form of respiratory pathology, most commonly
The bile acids, deoxycholic acid and ursodeoxycholic acid, regulate colonic epithelial wound healing
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 314:G378-G387
The intestinal epithelium constitutes an innate barrier which, upon injury, undergoes self-repair processes known as restitution. Although bile acids are known as important regulators of epithelial function in health and disease, their effects on wou
Autor:
Georgia M. Carroll, Bridie J. Goggins, Peter Pockney, Samwel Makanyengo, Stephen R. Smith, Simon Keely
Publikováno v:
The Journal of surgical research. 249
Background Anastomotic leak rates have not improved over several decades despite improvements in surgical techniques and patient care. The gut microbiome has been implicated in the development of leaks. The exact mechanisms by which tissue oxygenatio
Autor:
Marie J. Parsons, Geoffrey W. McCaughan, Prema M. Nair, Brett Nixon, Rachel Neal, Samwel Makanyengo, David A. Skerrett-Byrne, Jinbiao Chen, Phil M. Hansbro, Andrea Mathe, Hock L. Tay, Sean P. Colgan, Gerald Holtmann, Alan W. Baird, Simon Keely, Wai S. Soh, Bridie J. Goggins, Kyra Minahan, Kening Fan, Gang Liu
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
Liver inflammation is a common extraintestinal manifestation in inflammatory bowel disease (IBD), yet, the mechanisms driving gut-liver axis inflammation remain poorly understood. IBD leads to a breakdown in the integrity of the intestinal barrier ca
Autor:
Grace Burns, Jessica Bruce, Marjorie M. Walker, Martin Veysey, Kyra Minahan, Raquel Cameron, Bridie J. Goggins, Simon Keely, Michael D. Potter, Andrea Mathe, Nick Powell, Jay C. Horvat, Paul S. Foster, Nicholas J. Talley, Prema M. Nair, Gerald Holtmann, Crystal Naudin
Publikováno v:
Gastroenterology. 160:S-95
Autor:
Simon Keely, Nicholas J. Talley, Kyra Minahan, Simonne Sherwin, Gang Liu, Bridie J. Goggins, Marjorie M. Walker, Wai S. Soh, Jay C. Horvat, Darryl A. Knight, Jessica Bruce, Jennifer Pryor, Andrea Mathe
Publikováno v:
Gastroenterology. 160:S-96