Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bridgit B. Bowskill"'
Autor:
Karina Thieme, Syamantak Majumder, Angela S. Brijmohan, Sri N. Batchu, Bridgit B. Bowskill, Tamadher A. Alghamdi, Suzanne L. Advani, M. Golam Kabir, Youan Liu, Andrew Advani
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CK
Externí odkaz:
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731
Autor:
Angela S. Brijmohan, Sri N. Batchu, Syamantak Majumder, Tamadher A. Alghamdi, Karina Thieme, Sarah McGaugh, Youan Liu, Suzanne L. Advani, Bridgit B. Bowskill, M. Golam Kabir, Laurette Geldenhuys, Ferhan S. Siddiqi, Andrew Advani
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
To contend with the deleterious effects of accumulating misfolded protein aggregates or damaged organelles cells rely on a system of quality control processes, among them the autophagy-lysosome pathway. This pathway is itself controlled by a master r
Externí odkaz:
https://doaj.org/article/c86c2dcce1284f3e9217269d289233bf
Autor:
Karina Thieme, Sri N. Batchu, Ferhan S. Siddiqi, Karthik K. Tennankore, Youan Liu, Syamantak Majumder, Bridgit B. Bowskill, Kathryn White, Penelope Poyah, Andrew Advani, Tamadher A. Alghamdi, M. Golam Kabir, Suzanne L. Advani, Laurette Geldenhuys
Publikováno v:
Journal of Clinical Investigation. 128:483-499
Histone protein modifications control fate determination during normal development and dedifferentiation during disease. Here, we set out to determine the extent to which dynamic changes to histones affect the differentiated phenotype of ordinarily q
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d434cc499d364dff51a35d2eb25a14
https://doi.org/10.1172/jci95946
https://doi.org/10.1172/jci95946
Autor:
Youan Liu, Syamantak Majumder, Karina Thieme, Bridgit B. Bowskill, Angela S. Brijmohan, Suzanne L. Advani, Andrew Advani, M. Golam Kabir, Sri N. Batchu, Tamadher A. Alghamdi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
The therapeutic targeting of prostanoid subtype receptors may slow the development of chronic kidney disease (CKD) through mechanisms that are distinct from those of upstream COX inhibition. Here, employing multiple experimental models of CKD, we stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fa4a1dab02a387742eecf069a7c318
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731
https://doaj.org/article/3c7f7c6c5c3f478c808baefc6898c731
Autor:
Warren L. Lee, Kathryn White, Youan Liu, Andrew Advani, Sri N. Batchu, Angela S. Brijmohan, Suzanne L. Advani, Syamantak Majumder, Kerri Thai, Bridgit B. Bowskill, Paymon M. Azizi
Publikováno v:
Diabetes. 65:1398-1409
Discovery of common pathways that mediate both pancreatic β-cell function and end-organ function offers the opportunity to develop therapies that modulate glucose homeostasis and separately slow the development of diabetes complications. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87fdbdd5cb7c2843041dd4b64842cc32
https://doi.org/10.2337/db15-0783
https://doi.org/10.2337/db15-0783
Autor:
Sri N, Batchu, Karina, Thieme, Farigol H, Zadeh, Tamadher A, Alghamdi, Veera Ganesh, Yerra, Mitchell J, Hadden, Syamantak, Majumder, M Golam, Kabir, Bridgit B, Bowskill, Danyal, Ladha, Anthony O, Gramolini, Kim A, Connelly, Andrew, Advani
Publikováno v:
Diabetes. 67(11)
Blood glucose-lowering therapies can positively or negatively affect heart function in type 2 diabetes, or they can have neutral effects. Dipeptidyl peptidase 4 (DPP-4) inhibitors lower blood glucose by preventing the proteolytic inactivation of gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed646ea32fe22679679e003d1c8ddff3
https://pubmed.ncbi.nlm.nih.gov/30150305
https://pubmed.ncbi.nlm.nih.gov/30150305
Autor:
Andrew Advani, Angela S. Brijmohan, Youan Liu, M. Golam Kabir, Sri N. Batchu, Sarah McGaugh, Syamantak Majumder, Tamadher A. Alghamdi, Ferhan S. Siddiqi, Laurette Geldenhuys, Karina Thieme, Suzanne L. Advani, Bridgit B. Bowskill
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
To contend with the deleterious effects of accumulating misfolded protein aggregates or damaged organelles cells rely on a system of quality control processes, among them the autophagy-lysosome pathway. This pathway is itself controlled by a master r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97be20c639a2a67cd603161ea6914e2d
https://doi.org/10.3389/fphar.2018.00034
https://doi.org/10.3389/fphar.2018.00034
Autor:
Veera Ganesh Yerra, Sri N. Batchu, Suzanne L. Advani, Youan Liu, Mitchell J. Hadden, Syamantak Majumder, Bridgit B. Bowskill, Laurette Geldenhuys, Tamadher A. Alghamdi, Andrew Advani, Ferhan S. Siddiqi
Publikováno v:
Diabetes. 67(12)
The posttranslational histone modifications that epigenetically affect gene transcription extend beyond conventionally studied methylation and acetylation patterns. By examining the means by which podocytes influence the glomerular endothelial phenot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743ae405769e88b2a659e65e98e198e5
https://pubmed.ncbi.nlm.nih.gov/30213824
https://pubmed.ncbi.nlm.nih.gov/30213824
Autor:
Claudia C. dos Santos, Suzanne L. Advani, Kathryn White, Bridgit B. Bowskill, Giuliana Guarna, Moustafa Abdalla, Pingzhao Hu, Kim A. Connelly, Ferhan S. Siddiqi, Kerri Thai, Andrew Advani, Syamantak Majumder
Publikováno v:
Journal of the American Society of Nephrology. 27:2021-2034
Epigenetic regulation of oxidative stress is emerging as a critical mediator of diabetic nephropathy. In diabetes, oxidative damage occurs when there is an imbalance between reactive oxygen species generation and enzymatic antioxidant repair. Here, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e5d143d11e7fb47b15f1a0764aae257
https://doi.org/10.1681/asn.2014090898
https://doi.org/10.1681/asn.2014090898
Autor:
Leslie Cham, Julie A. Lovshin, Syamantak Majumder, Bridgit B. Bowskill, Suzanne L. Advani, Andrew Advani, Daniel C. Cattran, Harindra Rajasekeran, M. Golam Kabir, Heather N. Reich, David Z.I. Cherney, Josephine Tse, Ian W. Gibson, Vesta Lai, Yuliya Lytvyn, Michelle A. Hladunewich, Petter Bjornstad, Manish M. Sood
Publikováno v:
American journal of physiology. Renal physiology. 314(3)
Focal segmental glomerulosclerosis (FSGS) is an important cause of nondiabetic chronic kidney disease (CKD). Sodium-glucose cotransporter 2 inhibition (SGLT2i) therapy attenuates the progression of diabetic nephropathy, but it remains unclear whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd82a7fe5e02bd81e77b5784819e3b5
https://pubmed.ncbi.nlm.nih.gov/29141939
https://pubmed.ncbi.nlm.nih.gov/29141939