Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Bridget Riggs"'
Autor:
Erin M. Siegel, Abidemi Ajidahun, Anders Berglund, Whitney Guerrero, Steven Eschrich, Ryan M. Putney, Anthony Magliocco, Bridget Riggs, Kathryn Winter, Jeff P. Simko, Jaffer A. Ajani, Chandan Guha, Gordon S. Okawara, Ibrahim Abdalla, Mark J. Becker, Joseph F. Pizzolato, Christopher H. Crane, Kevin D. Brown, David Shibata
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
HPV infection results in changes in host gene methylation which, in turn, are thought to contribute to the neoplastic progression of HPV-associated cancers. The objective of this study was to identify joint and disease-specific genome-wide methylatio
Externí odkaz:
https://doaj.org/article/e15cc7c1d59a465bac60f535270348c7
Autor:
Jonathan M Hernandez, Erin M Siegel, Bridget Riggs, Steven Eschrich, Abul Elahi, Xiaotao Qu, Abidemi Ajidahun, Anders Berglund, Domenico Coppola, William M Grady, Anna R Giuliano, David Shibata
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50533 (2012)
Changes in host tumor genome DNA methylation patterns are among the molecular alterations associated with HPV-related carcinogenesis. However, there is little known about the epigenetic changes associated specifically with the development of anal squ
Externí odkaz:
https://doaj.org/article/fadb7b2ef1874cc7b1a31112dff65acf
Autor:
Anupam Pradhan, Eknath Naik, Arnut Paothong, Erin M. Siegel, Rachita Das, Valerie E. Whiteman, Lindsey M. King, Hamisu M. Salihu, Bridget Riggs
Publikováno v:
Journal of perinatal medicine. 45(9)
Aim:We sought to determine the association between prenatal smoking status and expression of fetal brain regulatory genes.Methods:At delivery, we collected information from parturient women on prenatal smoking habits and analyzed salivary cotinine le
Autor:
Hamisu M. Salihu, Valerie E. Whiteman, Roger Zoorob, Arnut Paothong, Karen Bruder, Bridget Riggs, Erin M. Siegel, Lindsey M. King, Anupam Pradhan, Rachel G. Sinkey, Adetola Louis-Jacques
Publikováno v:
American journal of perinatology. 33(6)
Objective Elevated homocysteine (HC) levels and/or shortened telomere length (TL) are associated with adverse medical conditions. Our objective is to investigate the relationship between HC and TL in cord blood leukocytes of newborns. Study Design Th
Autor:
Amber L. Delmas, Russell P. Darst, Erin M. Siegel, Eugene Izumchenko, Bridget Riggs, Lisa Dyer, Michael P. Kladde, Carolina E. Pardo, Mänette Monroe, Ardeshir Hakam, Kevin D. Brown
Publikováno v:
Carcinogenesis. 32:1625-1633
Aberrant activation of the Wnt/β-catenin signaling axis is a prominent oncogenic mechanism in numerous cancers including cervical cancer. Wnt inhibitory factor-1 (WIF1) is a secreted protein that binds Wnt and antagonizes Wnt activity. While the WIF
Autor:
Lindsey M. King, Valerie E. Whiteman, Anupam Pradhan, Rachel G. Sinkey, Erin M. Siegel, Jason L. Salemi, Bridget Riggs, Adetola Louis-Jacques, Hamisu M. Salihu, Arnut Paothong
Publikováno v:
Nutrition research (New York, N.Y.). 36(7)
Telomere length (TL) has been studied extensively in adults; however, limited information exists regarding maternal influences on TL in utero. The objective of this study was to investigate the relationship between fetal red blood cell (RBC) folate l
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0122495 (2015)
PLoS ONE, Vol 10, Iss 3, p e0122495 (2015)
Aberrant DNA methylation has been observed in cervical cancer; however, most studies have used non-quantitative approaches to measure DNA methylation. The objective of this study was to quantify methylation within a select panel of genes previously i
Autor:
Bridget Riggs, Ryan Putney, Steven A. Eschrich, Abidemi Ajidahun, Anders Berglund, Erin M. Siegel, David Shibata, Domenico Coppola
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 23(12)
Background: Epigenome-wide association studies are emerging in the field of cancer epidemiology with the rapid development of large-scale methylation array platforms. Until recently, these methods were only valid for DNA from flash frozen (FF) tissue
Autor:
Sarah E. Hoffe, Mark Becker, Joseph F. Pizzolato, Anders Berglund, Abidemi Ajidahun, Jennifer Moughan, Jeff Simko, Christopher H. Crane, Bridget Riggs, Chandan Guha, Steven A. Eschrich, David Shibata, Anthony Martin Magliocco, Ryan Putney, Gordon Okawara, Jaffer A. Ajani, John W. Clouse, Erin M. Siegel
Publikováno v:
Journal of Clinical Oncology. 35:588-588
588 Background: Genome-wide epigenetic events appear to play a role in the development and behavior of HPV+ cancers. The value of adjuvant therapy following chemoradiation for localized anal cancer (AC) remains unclear. Molecular prognostication to i
Autor:
Steven A. Eschrich, Jeff Simko, David Shibata, Anders Berglund, Abidemi Ajidahun, Jaffer A. Ajani, Kathryn Winter, Anthony M. Magliocco, Erin M. Siegel, Bridget Riggs, Sarah E. Hoffe, Abul Elahi, Jennifer Moughan
Publikováno v:
Diseases of the colon and rectum. 57(8)
BACKGROUND The Radiation Therapy Oncology Group 98-11 clinical trial demonstrated the superiority of standard 5-fluorouracil/mitomycin-C over 5-fluorouracil/cisplatin in combination with radiation in the treatment of anal squamous cell cancer. Tumor