Zobrazeno 1 - 10 of 42 pro vyhledávání: '"Bridget P. Keenan"'
1
Akademický článek
Creation of a sustainable longitudinal women in Leadership Development (WILD) curriculum focused on graduate medical education trainees
Autor: Colleen A. McGourty, Francine Castillo, Grace Donzelli, Bridget P. Keenan, Margaret Gilbreth, Lekshmi Santhosh
Publikováno v: BMC Medical Education, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Background Although women comprise the majority of medical students, gender disparities emerge early and remain at the highest levels of academia. Most leadership courses focus on faculty or students rather than women graduate medical educat
Externí odkaz: https://doaj.org/article/005457b9d8fc49858eeefebf9b08c928
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2
Akademický článek
A robust ensemble feature selection approach to prioritize genes associated with survival outcome in high-dimensional gene expression data
Autor: Phi Le, Xingyue Gong, Leah Ung, Hai Yang, Bridget P. Keenan, Li Zhang, Tao He
Publikováno v: Frontiers in Systems Biology, Vol 4 (2024)
Exploring features associated with the clinical outcome of interest is a rapidly advancing area of research. However, with contemporary sequencing technologies capable of identifying over thousands of genes per sample, there is a challenge in constru
Externí odkaz: https://doaj.org/article/a845c2977dcf43798780ba07759f8b5f
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3
Akademický článek
Immunotherapy in hepatocellular carcinoma: the complex interface between inflammation, fibrosis, and the immune response
Autor: Bridget P. Keenan, Lawrence Fong, Robin K. Kelley
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-13 (2019)
Abstract Hepatocellular carcinoma (HCC) is the third leading cause of cancer deaths worldwide and confers a poor prognosis. Beyond standard systemic therapy with multikinase inhibitors, recent studies demonstrate the potential for robust and durable
Externí odkaz: https://doaj.org/article/8c8cc4c3425442f0bdc4b0717edaf549
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4
Structural Sexism and Cancer Care: The Effects on the Patient and Oncologist
Autor: Bridget P. Keenan, Elizabeth Barr, Elizabeth Gleeson, Caprice Christian Greenberg, Sarah M. Temkin
Publikováno v: American Society of Clinical Oncology Educational Book.
Despite progress toward equity within our broad social context, the domains of gender as a social, cultural, and structural variable continue to exert influence on the delivery of oncology care. Although there have been vast advances in our understan
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ca390f8d8f2befe22ea1073b8b780bf
https://doi.org/10.1200/edbk_391516
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5
Data from Inhibition of miR-21 Regulates Mutant KRAS Effector Pathways and Intercepts Pancreatic Ductal Adenocarcinoma Development
Autor: Jacquelyn W. Zimmerman, Elizabeth M. Jaffee, Todd D. Armstrong, Aleksandra Popovic, Bridget P. Keenan, Alexander C. Hopkins, Minwei Cao, Elana J. Fertig, Robert A. Anders, Nina J. Chu
Almost all pancreatic ductal adenocarcinomas (PDA) develop following KRAS activation, which triggers epithelial transformation and recruitment of desmoplastic stroma through additional transcriptional and epigenetic regulation, but only a few of thes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::372c7823cf6422082f233f2664b6e472
https://doi.org/10.1158/1940-6207.c.6547637.v1
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9
Key challenges for drugs in clinical development for cholangiocarcinoma
Autor: R. Kate Kelley, Bridget P. Keenan
Publikováno v: Expert Opinion on Investigational Drugs. 30:285-290
Cholangiocarcinoma (CCA) is a highly morbid cancer with rising incidence and few approved standard therapies. The main anatomical sites of cholangiocarcinoma are intra-hepatic (iCCA), perihilar, an...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2595e60531ff8fb593214270c43a3d7b
https://doi.org/10.1080/13543784.2021.1880565
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10
A phase II study of hypofractionated radiation therapy to augment immune response in patients with metastatic gastrointestinal malignancies progressing on immune therapy (ARM-GI)
Autor: Hewitt Chang, Luchia Andemicael, Moshiur Mekhail Anwar, John Gordan, Jamese Johnson, Bridget P Keenan, Robin Kate Kelley, Andrew H. Ko, Katherine Van Loon, Alan P. Venook, Lawrence Fong, Melody Ju Xu, Mary Uan-Sian Feng
Publikováno v: Journal of Clinical Oncology. 41:TPS817-TPS817
TPS817 Background: Metastatic disease remains a consistent challenge for patients with gastrointestinal (GI) malignancies. Multiple immune checkpoint inhibitors (ICI) have been FDA approved for several GI indications. Still, patients will progress on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4979707815ff330bc93ac52721136047
https://doi.org/10.1200/jco.2023.41.4_suppl.tps817
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