Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Bridget Nieto"'
Publikováno v:
Physiological Reports, Vol 12, Iss 6, Pp n/a-n/a (2024)
Abstract Cardiac fibroblasts (CFs) are an attractive target for reducing pathological cardiac remodeling, and understanding the underlying mechanisms of these processes is the key to develop successful therapies for treating the pressure‐overloaded
Externí odkaz:
https://doaj.org/article/cba148bde38f493782151afd489ec03e
Publikováno v:
Physiology. 38
Introduction: Mechanical stress (e.g., pressure overload), cytokines, growth factors, and neurohumoral mediators stimulate cardiac fibroblast (CF) activation, which promotes extracellular matrix (ECM) protein synthesis leading to cardiac fibrosis and
Autor:
Isabel Chaput, Madeline Kelly, Maria Landherr, Iuliia Polina, Bridget Nieto, Michael Cypress, Bong Sook Jhun, Peng Zhang, Jin O-Uchi
Publikováno v:
Physiology. 38
Introduction: A mitochondrial fusion protein, Mitofusin 2 (Mfn2) serves as one of the major components for tethering the mitochondria and endoplasmic reticulum (ER), which regulates the exchange of lipids, Ca2+, and reactive oxygen species (ROS) acro