Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Bridget M Deasy"'
Autor:
Giovanna Distefano, Ricardo Jose Ferrari, Christopher Weiss, Bridget M Deasy, Michael L Boninger, G Kelley Fitzgerald, Johnny Huard, Fabrisia Ambrosio
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e54922 (2013)
Cellular therapy is a potential approach to improve the regenerative capacity of damaged or diseased skeletal muscle. However, its clinical use has often been limited by impaired donor cell survival, proliferation and differentiation following transp
Externí odkaz:
https://doaj.org/article/a649ee5e722441c28c975f111183dacb
Autor:
Ricardo José Ferrari, Bret H. Goodpaster, Elke H. P. Brown, Giovanna Distefano, Yesica Garciafigueroa, Alexandra Roperti, Donna B. Stolz, Bridget M. Deasy, Fabrisia Ambrosio, Aaron Barchowsky, Amin Cheikhi
Publikováno v:
Free Radical Biology and Medicine. 74:64-73
Over 4 million individuals in the United States, and over 140 million individuals worldwide, are exposed daily to arsenic-contaminated drinking water. Human exposures can range from below the current limit of 10 μg/L to over 1mg/L, with 100 μg/L pr
Autor:
Burhan Gharaibeh, Johnny Huard, Guangheng Li, Jonathan B. Pollett, Bruno Péault, Lauren Drowley, Arvydas Usas, Bin Sun, William C.W. Chen, Bridget M. Deasy, Bo Zheng
Publikováno v:
Journal of Orthopaedic Research. 31:1089-1095
We have previously reported the high regenerative potential of murine muscle-derived stem cells (mMDSCs) that are capable of differentiating into multiple mesodermal cell lineages, including myogenic, endothelial, chondrocytic, and osteoblastic cells
Autor:
Bridget M. Deasy, Doug J. Koebler, Yong Li, Taylor A. Bissell, Steven M. Chirieleison, Jordan E. Anderson, Christopher C. Scelfo
Publikováno v:
Biotechnology Progress. 27:913-924
Automated time-lapsed microscopy provides unique research opportunities to visualize cells and subcellular components in experiments with time-dependent parameters. As accessibility to these systems is increasing, we review here their use in cell sci
Autor:
Chien Wen Chen, Pang Ning Teng, Johnny Huard, Bridget M. Deasy, Ludovic Zimmerlin, Bruno Péault, Bin Sun, Manuela Gavina, Tea Soon Park
Publikováno v:
Park, T S, Gavina, M, Chen, C-W, Sun, B, Teng, P-N, Huard, J, Deasy, B M, Zimmerlin, L & Peault, B 2011, ' Placental Perivascular Cells for Human Muscle Regeneration ', Stem Cells and Development, vol. 20, no. 3, pp. 451-463 . https://doi.org/10.1089/scd.2010.0354
Perivascular multipotent mesenchymal progenitors exist in a variety of tissues, including the placenta. Here, we suggest that the abundant vasculature present in the human placenta can serve as a source of myogenic cells to regenerate skeletal muscle
Autor:
Steven M. Chirieleison, Bridget M. Deasy, Matthew J. Peyton, Taylor A. Bissell, Ashley M. Witt
Publikováno v:
Operative Techniques in Orthopaedics. 20:127-135
Stem cell therapy and tissue engineering offer great potential for the treatment of a variety of musculoskeletal disorders. However, the study of stem cells is challenged to identify the most robust cells and control the fate of those cells. Live cel
Autor:
James D. Kang, Gwendolyn Sowa, Nam Vo, Helga I. Georgescu, Hyoung Yeon Seo, Bridget M. Deasy, Joo Han Kim, Rebecca K. Studer
Publikováno v:
Spine. 34:2486-2493
STUDY DESIGN We demonstrated the differentiation of notochordal cells by direct observation using a live automated cell imaging system. We also hypothesized that notochordal cells have characteristics of chondrocyte-like cells. OBJECTIVE To determine
Publikováno v:
Molecular Therapy. 17:1788-1798
We have isolated a population of muscle-derived stem cells (MDSCs) that, when compared with myoblasts, display an improved regeneration capacity, exhibit better cell survival, and improve myogenesis and angiogenesis. In addition, we and others have o
Publikováno v:
Experimental Cell Research. 315:2963-2973
The objective of the present study was to evaluate how different ligand interactions of profilin-1 (Pfn1), an actin-binding protein that is upregulated during capillary morphogenesis of vascular endothelial cells (VEC), contribute to migration and ca
Autor:
Bradley B. Keller, Kimimasa Tobita, Kenneth L. Urish, Johnny Huard, Joseph B. Vella, Baohong Cao, Masaho Okada, Bridget M. Deasy, Jon D. Piganelli
Publikováno v:
Molecular Biology of the Cell. 20:509-520
Stem cells are classically defined by their multipotent, long-term proliferation, and self-renewal capabilities. Here, we show that increased antioxidant capacity represents an additional functional characteristic of muscle-derived stem cells (MDSCs)