Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Bridget Lollo"'
Autor:
Larry Gold, Deborah Ayers, Jennifer Bertino, Christopher Bock, Ashley Bock, Edward N Brody, Jeff Carter, Andrew B Dalby, Bruce E Eaton, Tim Fitzwater, Dylan Flather, Ashley Forbes, Trudi Foreman, Cate Fowler, Bharat Gawande, Meredith Goss, Magda Gunn, Shashi Gupta, Dennis Halladay, Jim Heil, Joe Heilig, Brian Hicke, Gregory Husar, Nebojsa Janjic, Thale Jarvis, Susan Jennings, Evaldas Katilius, Tracy R Keeney, Nancy Kim, Tad H Koch, Stephan Kraemer, Luke Kroiss, Ngan Le, Daniel Levine, Wes Lindsey, Bridget Lollo, Wes Mayfield, Mike Mehan, Robert Mehler, Sally K Nelson, Michele Nelson, Dan Nieuwlandt, Malti Nikrad, Urs Ochsner, Rachel M Ostroff, Matt Otis, Thomas Parker, Steve Pietrasiewicz, Daniel I Resnicow, John Rohloff, Glenn Sanders, Sarah Sattin, Daniel Schneider, Britta Singer, Martin Stanton, Alana Sterkel, Alex Stewart, Suzanne Stratford, Jonathan D Vaught, Mike Vrkljan, Jeffrey J Walker, Mike Watrobka, Sheela Waugh, Allison Weiss, Sheri K Wilcox, Alexey Wolfson, Steven K Wolk, Chi Zhang, Dom Zichi
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e15004 (2010)
The interrogation of proteomes ("proteomics") in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology and medicine.We present a new aptamer-based proteomic technology for biomarker discovery capable of simultane
Externí odkaz:
https://doaj.org/article/60cf7be12d92486ea0f48de33701edfa
Publikováno v:
PROTEOMICS. 14:638-644
Antibodies have been the workhorse reagents of protein capture and quantification since their 1959 debut in the RIAs developed by Yalow and Berson. However, there are technical challenges to the use of antibodies in highly multiplexed arrays aimed at
Autor:
Jill Giles-Komar, Thomas J. Malia, Shanrong Zhao, Yiqing Feng, Ellen Chi, Walter Nishioka, Bridget Lollo, Gary L. Gilliland, Johan E. S. Fransson, Ronald V. Swanson, Juan Carlos Almagro, Thai Dinh, Wendy Cordier, Galina Obmolova, Yonghong Zhao, Gopalan Raghunathan, Alexey Teplyakov
Publikováno v:
Journal of Molecular Biology. 398:214-231
Humanization of a potent neutralizing mouse anti-human IL-13 antibody (m836) using a method called human framework adaptation (HFA) is reported. HFA consists of two steps: human framework selection (HFS) and specificity-determining residue optimizati
Autor:
Stephan Kraemer, Christopher Bock, Jonathan D. Vaught, Bridget Lollo, Alex Stewart, Martin Stanton, Malti Nikrad, Jeffrey J. Walker, Larry Gold, Tracy R. Keeney
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 14:360-366
At SomaLogic, we have embarked on an ambitious program of clinical studies using a novel aptamerbased proteomics technology to discover biomarkers and develop new tools to diagnose, understand, and treat human disease. As part of this program, we des
Autor:
Sheri L. Booten, Sanjay K. Pandey, Susan M. Freier, Amuthakannan Subramaniam, Susan F. Murray, Christine Esau, Lynnetta Watts, Scott Davis, Mark J. Graham, Michael Pear, Brett P. Monia, Stephanie Propp, Bridget Lollo, C. Frank Bennett, Robert Mckay, Sanjay Bhanot, Xing Xian Yu
Publikováno v:
Cell Metabolism. 3:87-98
Summary Current understanding of microRNA (miRNA) biology is limited, and antisense oligonucleotide (ASO) inhibition of miRNAs is a powerful technique for their functionalization. To uncover the role of the liver-specific miR-122 in the adult liver,
Publikováno v:
Analytical Biochemistry. 359:268-270
Autor:
John C. Rohloff, Susan Jennings, Stephan Kraemer, Edward N. Brody, Mike Mehan, Evaldas Katilius, Jeffrey J. Walker, Ashley Bock, Shashi Kumar Gupta, Robert Mehler, Jeffrey D. Carter, Sally K. Nelson, Michele Nelson, Cate Fowler, Mike Watrobka, Bruce E. Eaton, Nebojsa Janjic, Thale C. Jarvis, Daniel Schneider, Suzanne Stratford, Ngan Le, Dennis Halladay, Deborah Ayers, Bridget Lollo, Sheri K. Wilcox, Glenn Sanders, Christopher Bock, Daniel I. Resnicow, Allison Weiss, Trudi Foreman, Sheela Waugh, Virginia Cunningham, Matt Otis, Tim Fitzwater, Martin Stanton, Tracy R. Keeney, Joe Heilig, Tad H. Koch, Gregory M. Husar, Larry Gold, Alex Stewart, Urs A. Ochsner, Nancy Kim, Britta Singer, Jennifer Bertino, Wes Mayfield, Daniel M. Levine, Mike Vrkljan, Meredith Goss, Malti Nikrad, Ashley Forbes, Jonathan D. Vaught, Thomas S. Parker, Luke Kroiss, Sarah Sattin, Dom Zichi, Alana Sterkel, Wes Lindsey, Alexey D. Wolfson, Steve Pietrasiewicz, Steve Wolk, Andrew B. Dalby, Brian Hicke, Rachel Ostroff, Jim Heil, Dylan Flather, Terese Kaske, Dan Nieuwlandt, Bharat Gawande, Chi Zhang, Magda Gunn
Publikováno v:
Nature Precedings
Interrogation of the human proteome in a highly multiplexed and efficient manner remains a coveted and challenging goal in biology. We present a new aptamer-based proteomic technology for biomarker discovery capable of simultaneously measuring thousa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edba1f85bc2044e505d070fd97874ae7
http://hdl.handle.net/10101/npre.2010.4538.1
http://hdl.handle.net/10101/npre.2010.4538.1
Publikováno v:
Nucleic Acids Research
MicroRNAs (miRNAs) are a class of 20–24 nt noncoding RNAs that regulate target mRNAs post-transcriptionally by binding with imperfect complementarity in the 3′-untranslated region (3′-UTR) and inhibiting translation or RNA stability. Current un
Autor:
Bridget Lollo, Susan M. Freier, Eigen R. Peralta, Chantal A Reed, C. Frank Bennett, Lisa M Wenrich, Charlene A Wong
Publikováno v:
Oligonucleotides. 15(1)
In an effort to optimize the transfection of cell lines with antisense oligonucleotides, we examined cellular accumulation of a labeled oligonucleotide by flow cytometry. We were surprised to observe that a routinely used transfection protocol, a fix
Autor:
Ravi Jain, Ranjan J. Perera, Eric G. Marcusson, Christine Esau, Xiaolin Kang, Richard H. Griffey, Yingqing Sun, Lingamanaidu V. Ravichandran, Susan M. Freier, C. Frank Bennett, Bridget Lollo, Elaine Hanson, Nicholas M. Dean, Seongjoon Koo, Eigen R. Peralta
Publikováno v:
The Journal of biological chemistry. 279(50)
MicroRNAs (miRNAs) are endogenously expressed 20-24 nucleotide RNAs thought to repress protein translation through binding to a target mRNA (1-3). Only a few of the more than 250 predicted human miRNAs have been assigned any biological function. In a