Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Bridget L. Leonard"'
Publikováno v:
Microscopy and Microanalysis. 18:50-67
The cardiac extracellular matrix (ECM) is the three-dimensional scaffold that defines the geometry and muscular architecture of the cardiac chambers and transmits forces produced during the cardiac cycle throughout the heart wall. The cardiac ECM is
Autor:
Kerry M. Loomes, Bridget L. Leonard, Lynda Whiting, Garth J. S. Cooper, Lance Yi Xu, Anthony R. J. Phillips, Edward W. Kraegen, Debbie L. Hay, Rachel N. Danaher
Publikováno v:
Endocrinology. 149:154-160
Alpha-calcitonin gene-related peptide (alphaCGRP) is released mainly from sensory and motor nerves in response to physiological stimuli. Despite well-documented pharmacological effects, its primary physiological role has thus far remained obscure. In
Autor:
G.A. Head, Simon C. Malpas, D.E. Burgess, P.C. Austin, Bridget L. Leonard, Sarah-Jane Guild, John V. Ringwood, Michael A. Navakatikyan
Publikováno v:
IEEE Engineering in Medicine and Biology Magazine. 20:17-24
This article focuses on how sympathetic nerve activity (SNA) contributes to the variability seen in blood pressure. Specifically, it examines the following questions: why do oscillations occur at certain frequencies, why do only certain frequencies o
Autor:
Garth J. S. Cooper, R. N. Watson, Anthony R. J. Phillips, Kerry M. Loomes, Bridget L. Leonard
Publikováno v:
Acta diabetologica. 42(4)
The Zucker diabetic fatty (ZDF) rat is a commonly used animal model of type 2 diabetes yet complete descriptions of insulin resistance in this model are limited. We present a full characterisation of in vivo insulin resistance in obese (fa/fa) animal
Autor:
Grant R. Allen, Bridget L. Leonard, Garth J. S. Cooper, Ajith Dissanayake, F. E. Leahy, John Richard Baker, Thomas K. Borg, Etuate L. Saafi, Geraldine F. Keogh, Adèle J. Pope, Robert N. Doughty, Dianne H. Brunton, Peter D. W. Boyd, Gregory D. Gamble, Yih-Kai Chan, Sally D. Poppitt, Brett R. Cowan, Anthony R. J. Phillips, Soon Y. Choong, Alistair A. Young, Christopher J. Occleshaw, David J. Crossman
Publikováno v:
Diabetes. 53(9)
Heart disease is the major cause of death in diabetes, a disorder characterized by chronic hyperglycemia and cardiovascular complications. Although altered systemic regulation of transition metals in diabetes has been the subject of previous investig
Autor:
Simon C. Malpas, Bridget L. Leonard, Sing Kiong Nguang, Carolyn J. Barrett, John V. Ringwood, Huang-Ku Liu, Sarah-Jane Guild, Michael A. Navakatikyan
Publikováno v:
American journal of physiology. Regulatory, integrative and comparative physiology. 283(2)
The aim in the present experiments was to assess the dynamic baroreflex control of blood pressure, to develop an accurate mathematical model that represented this relationship, and to assess the role of dynamic changes in heart rate and stroke volume
Autor:
Simon C. Malpas, Bridget L. Leonard
Publikováno v:
Clinical and experimental pharmacologyphysiology. 27(12)
1. The importance of renal sympathetic nerve activity (RSNA) in the regulation of renal function is well established. However, it is less clear how the renal vasculature responds to the different mean levels and patterns of RSNA. While many studies h
Publikováno v:
Autonomic neuroscience : basicclinical. 83(1-2)
Renal sympathetic nerve activity (RSNA) and renal blood flow (RBF) both show oscillations at various frequencies but the functional significance and regulation of these oscillations is not well understood. To establish whether the strength of these o
Publikováno v:
Europe PubMed Central
To test whether renal sympathetic nerve activity (RSNA) can differentially regulate blood flow in the renal medulla (MBF) and cortex (CBF) of pentobarbital sodium-anesthetized rabbits, we electrically stimulated the renal nerves while recording total
Publikováno v:
Heart, Lung and Circulation. 19:S73