Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Bridget L Stocker"'
Autor:
Friederike Behler-Janbeck, Tomotsugu Takano, Regina Maus, Jennifer Stolper, Danny Jonigk, Meritxell Tort Tarrés, Thomas Fuehner, Antje Prasse, Tobias Welte, Mattie S M Timmer, Bridget L Stocker, Yoichi Nakanishi, Tomofumi Miyamoto, Sho Yamasaki, Ulrich A Maus
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006038 (2016)
Among various innate immune receptor families, the role of C-type lectin receptors (CLRs) in lung protective immunity against Streptococcus pneumoniae (S. pneumoniae) is not fully defined. We here show that Mincle gene expression was induced in alveo
Externí odkaz:
https://doaj.org/article/81156be761144f3f8ba8235b42f48edb
Autor:
Sandeep K. Gupta, Natalie Parlane, Benjamin Bridgeman, Amy T. Lynch, Emma M. Dangerfield, Mattie S. M. Timmer, Bridget L. Stocker, D. Neil Wedlock
Publikováno v:
PLoS ONE, Vol 18, Iss 1 (2023)
Bronchopneumonia is a common respiratory disease in livestock. Mannheimia haemolytica is considered the main causative pathogen leading to lung damage in sheep, with Mycoplasma ovipneumoniae and ParaInfluenza virus type 3, combined with adverse physi
Externí odkaz:
https://doaj.org/article/7f2be68a4d8142f4bdb6e915f369aad0
Autor:
M. A. Thathsaranie P. Manthrirathna, Emma M. Dangerfield, Shigenari Ishizuka, Aodhamair Woods, Brenda S. Luong, Sho Yamasaki, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The tremendous potential of trehalose glycolipids as vaccine adjuvants has incentivized the study of how the structures of these ligands relate to their Mincle-mediated agonist activities. Despite this, structure-activity work in the field has been l
Externí odkaz:
https://doaj.org/article/fd1b5f482d3140fa8c3f169c60e6a0aa
Autor:
Kristel Kodar, Emma M. Dangerfield, Amy J. Foster, Devlin Forsythe, Shigenari Ishizuka, Melanie J. McConnell, Sho Yamasaki, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
Inflammation.
Abstract—α,α′-Trehalose 6,6′-glycolipids have long been known for their immunostimulatory properties. The adjuvanticity of α,α′-trehalose 6,6′-glycolipids is mediated by signalling through the macrophage inducible C-type lectin (Mincle)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac3db86c06f1d4148f70500cb9a3db1b
https://doi.org/10.1007/s10753-023-01814-5
https://doi.org/10.1007/s10753-023-01814-5
Autor:
Garth Cameron, Janice M. H. Cheng, Dale I. Godfrey, Mattie S. M. Timmer, Bridget L. Stocker, Emma M. Dangerfield
Publikováno v:
RSC Advances. 12:18493-18500
Isoglobotrihexosylceramide (iGb3) is a known NKT cell agonist, however the specific interactions required to trigger NKT cell TCR activation in response to this mammalian glycolipid are not fully understood. Here we report the synthesis of 1,3-β-Gal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579578e835992a75a76818ee2f820b7d
https://doi.org/10.1039/d2ra02373c
https://doi.org/10.1039/d2ra02373c
Autor:
Chriselle D. Braganza, Kristel Kodar, Thomas Teunissen, Sarah K. Andreassend, Ayesha Khan, Mattie S. M. Timmer, Bridget L. Stocker
Publikováno v:
Organic & Biomolecular Chemistry. 20:3096-3104
Macrophage inducible C-type lectin (Mincle) is a pattern recognition receptor on myeloid cells that represents a promising target for Th1-stimulating adjuvants. We report on the synthesis of branched and aromatic glucose monoesters and glycosides and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3812e0a4ece9e2c0b6d301dd88f8496
https://doi.org/10.1039/d1ob02111g
https://doi.org/10.1039/d1ob02111g
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 72, Iss 3, Pp 340-342 (2016)
The structure of the title compound, C12H23N5O6, solved using adequate data from a thin crystal plate, confirmed that this useful glycoconjugate was obtained in the ring-closed β-pyranose configuration with 4C1 conformation. The molecules are bound
Externí odkaz:
https://doaj.org/article/6ccdfb64fee849e78e9fba158f1843e2
Publikováno v:
ACS omega. 7(33)
The development of a one-step amination-cyclization cascade reaction for the synthesis of N-substituted iminosugars from iodo-pentoses and hexoses is reported. This novel methodology allows for the stereoselective conversion of easily accessible iodo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71afcb27db21b963c2b3d76e6bcb6685
https://pubmed.ncbi.nlm.nih.gov/36033662
https://pubmed.ncbi.nlm.nih.gov/36033662
Autor:
M.A. Thathsaranie P. Manthrirathna, Kristel Kodar, Shigenari Ishizuka, Emma M. Dangerfield, Lu Xiuyuan, Sho Yamasaki, Bridget L. Stocker, Mattie S. M. Timmer
Publikováno v:
Bioorganic Chemistry. 133:106345
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93c292319e7e1e0e8a99f520f59007dc
https://doi.org/10.1016/j.bioorg.2023.106345
https://doi.org/10.1016/j.bioorg.2023.106345
Autor:
Nathaniel J. L. K. Davis, Matthew W. Brett, Bridget L. Stocker, Isabella Wagner, Mattie S. M. Timmer, Jake Hardy, Michael Price, Kai Chen, Aurélien Rossi
Publikováno v:
The Journal of Physical Chemistry C. 125:1447-1453
Cesium lead halide perovskite nanocrystals show great promise for optoelectronic applications due to their thermal stability, wide absorption range, and intense photoluminescence. These properties ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1af966301d34804f15a9662d9278c094
https://doi.org/10.1021/acs.jpcc.0c09161
https://doi.org/10.1021/acs.jpcc.0c09161