Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Bridget E, Barber"'
Autor:
Reena Mukhiya, Wim A. Fleischmann, Jessica R. Loughland, Jo-Anne Chan, Fabian de Labastida Rivera, Dean Andrew, James G. Beeson, James S. McCarthy, Bridget E. Barber, J. Alejandro Lopez, Christian Engwerda, Richard Thomson-Luque, Michelle J. Boyle
Publikováno v:
EBioMedicine, Vol 109, Iss , Pp 105419- (2024)
Summary: Background: Human immune responses to infection and vaccination are heterogenous, driven by multiple factors including genetics, environmental exposures and personal infection histories. For malaria caused by Plasmodium falciparum parasites,
Externí odkaz:
https://doaj.org/article/61b334fc1a284054a6f4ac3e995a4b50
Autor:
Pengxing Cao, Steven Kho, Matthew J. Grigg, Bridget E. Barber, Kim A. Piera, Timothy William, Jeanne R. Poespoprodjo, Ihn Kyung Jang, Julie A. Simpson, James M. McCaw, Nicholas M. Anstey, James S. McCarthy, Sumudu Britton
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Plasmodium vivax lactate dehydrogenase (PvLDH) is an essential enzyme in the glycolytic pathway of P. vivax. It is widely used as a diagnostic biomarker and a measure of total-body parasite biomass in vivax malaria. However, the dynamics of
Externí odkaz:
https://doaj.org/article/d48ba3507e1249c79abee4305c434258
Autor:
Angelica F Tan, Sitti Saimah Binti Sakam, Kim Piera, Giri S Rajahram, Timothy William, Bridget E Barber, Nicholas M Anstey, Matthew J Grigg, Steven Kho
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 8, p e0012424 (2024)
The risk of severe malaria from the zoonotic parasite Plasmodium knowlesi approximates that from P. falciparum. In severe falciparum malaria, neutrophil activation contributes to inflammatory pathogenesis, including acute lung injury (ALI). The role
Externí odkaz:
https://doaj.org/article/6ba15fe81694409a834abc0b8f340f3c
Autor:
Stephen D. Woolley, Matthew J. Grigg, Louise Marquart, Jeremy S.E. Gower, Kim Piera, Arya Sheela Nair, Fiona M. Amante, Giri S. Rajahram, Timothy William, David M. Frazer, Stephan Chalon, James S. McCarthy, Nicholas M. Anstey, Bridget E. Barber
Publikováno v:
EBioMedicine, Vol 105, Iss , Pp 105189- (2024)
Summary: Background: The interaction between iron status and malaria is incompletely understood. We evaluated longitudinal changes in iron homeostasis in volunteers enrolled in malaria volunteer infection studies (VIS) and in Malaysian patients with
Externí odkaz:
https://doaj.org/article/cacdf27f70df4dd7b2ca25c9e1760fa9
Autor:
Nicholas L. Dooley, Tinashe G. Chabikwa, Zuleima Pava, Jessica R. Loughland, Julianne Hamelink, Kiana Berry, Dean Andrew, Megan S. F. Soon, Arya SheelaNair, Kim A. Piera, Timothy William, Bridget E. Barber, Matthew J. Grigg, Christian R. Engwerda, J. Alejandro Lopez, Nicholas M. Anstey, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Plasmodium falciparum malaria drives immunoregulatory responses across multiple cell subsets, which protects from immunopathogenesis, but also hampers the development of effective anti-parasitic immunity. Understanding malaria induced tolero
Externí odkaz:
https://doaj.org/article/d4f0ae647bca412fa846c8d4ab492791
Autor:
Angelica F. Tan, Priyaleela Thota, Sitti Saimah Binti Sakam, Yao Long Lew, Giri S. Rajahram, Timothy William, Bridget E. Barber, Steven Kho, Nicholas M. Anstey, David Bell, Matthew J. Grigg
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Plasmodium knowlesi is the major cause of zoonotic malaria in Southeast Asia. Rapid and accurate diagnosis enables effective clinical management. A novel malaria diagnostic tool, Gazelle (Hemex Health, USA) detects haemozoin, a by-product of
Externí odkaz:
https://doaj.org/article/51cabcc3b230470fb930eceb70eadb59
Autor:
Yulin Wang, Fabian De Labastida Rivera, Chelsea L. Edwards, Teija C.M. Frame, Jessica A. Engel, Luzia Bukali, Jinrui Na, Susanna S. Ng, Dillon Corvino, Marcela Montes de Oca, Patrick T. Bunn, Megan S.F. Soon, Dean Andrew, Jessica R. Loughland, Jia Zhang, Fiona H. Amante, Bridget E. Barber, James S. McCarthy, J. Alejandro Lopez, Michelle J. Boyle, Christian R. Engwerda
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
The development of highly effective malaria vaccines and improvement of drug-treatment protocols to boost antiparasitic immunity are critical for malaria elimination. However, the rapid establishment of parasite-specific immune regulatory networks fo
Externí odkaz:
https://doaj.org/article/3c2a3ba4c5594fffbb78ac8fa7298d0d
Autor:
Jeyamalar T. Thurai Rathnam, Matthew J. Grigg, Saber Dini, Timothy William, Sitti Saimah Sakam, Daniel J. Cooper, Giri S. Rajahram, Bridget E. Barber, Nicholas M. Anstey, Ali Haghiri, Megha Rajasekhar, Julie A. Simpson
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-13 (2023)
Abstract Background The incidence of zoonotic Plasmodium knowlesi infections in humans is rising in Southeast Asia, leading to clinical studies to monitor the efficacy of anti-malarial treatments for knowlesi malaria. One of the key outcomes of anti-
Externí odkaz:
https://doaj.org/article/9264b50a5c56427db4cdcce28b8e8fa0
Autor:
Steven Kho, Nicholas M. Anstey, Bridget E. Barber, Kim Piera, Timothy William, Enny Kenangalem, James S. McCarthy, Ihn Kyung Jang, Gonzalo J. Domingo, Sumudu Britton, Matthew J. Grigg
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Commercial point-of-care tests remain insufficient for accurately detecting and differentiating low-level malaria infections in regions co-endemic with multiple non-falciparum species, including zoonotic Plasmodium knowlesi (Pk). A 5-plex ch
Externí odkaz:
https://doaj.org/article/f431d93e67034c118708832962c78c62
Autor:
John Woodford, Ashley Gillman, Peter Jenvey, Jennie Roberts, Stephen Woolley, Bridget E. Barber, Melissa Fernandez, Stephen Rose, Paul Thomas, Nicholas M. Anstey, James S. McCarthy
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract Cerebral malaria is the most serious manifestation of severe falciparum malaria. Sequestration of infected red blood cells and microvascular dysfunction are key contributing processes. Whether these processes occur in early stage disease pri
Externí odkaz:
https://doaj.org/article/81d9e29face44fec8a3919b85f849f9d