Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Bridget Currell"'
Autor:
Xiaofeng Xin, David Gfeller, Jackie Cheng, Raffi Tonikian, Lin Sun, Ailan Guo, Lianet Lopez, Alevtina Pavlenco, Adenrele Akintobi, Yingnan Zhang, Jean‐François Rual, Bridget Currell, Somasekar Seshagiri, Tong Hao, Xinping Yang, Yun A Shen, Kourosh Salehi‐Ashtiani, Jingjing Li, Aaron T Cheng, Dryden Bouamalay, Adrien Lugari, David E Hill, Mark L Grimes, David G Drubin, Barth D Grant, Marc Vidal, Charles Boone, Sachdev S Sidhu, Gary D Bader
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp 1-17 (2013)
Abstract Src homology 3 (SH3) domains bind peptides to mediate protein–protein interactions that assemble and regulate dynamic biological processes. We surveyed the repertoire of SH3 binding specificity using peptide phage display in a metazoan, th
Externí odkaz:
https://doaj.org/article/fcff853d9bf24f249607d4cc31797396
Autor:
Raffi Tonikian, Xiaofeng Xin, Christopher P Toret, David Gfeller, Christiane Landgraf, Simona Panni, Serena Paoluzi, Luisa Castagnoli, Bridget Currell, Somasekar Seshagiri, Haiyuan Yu, Barbara Winsor, Marc Vidal, Mark B Gerstein, Gary D Bader, Rudolf Volkmer, Gianni Cesareni, David G Drubin, Philip M Kim, Sachdev S Sidhu, Charles Boone
Publikováno v:
PLoS Biology, Vol 7, Iss 10, p e1000218 (2009)
SH3 domains are peptide recognition modules that mediate the assembly of diverse biological complexes. We scanned billions of phage-displayed peptides to map the binding specificities of the SH3 domain family in the budding yeast, Saccharomyces cerev
Externí odkaz:
https://doaj.org/article/8523eb39b4ed44aa980f11ba6972eb54
Autor:
Raffi Tonikian, Yingnan Zhang, Stephen L Sazinsky, Bridget Currell, Jung-Hua Yeh, Boris Reva, Heike A Held, Brent A Appleton, Marie Evangelista, Yan Wu, Xiaofeng Xin, Andrew C Chan, Somasekar Seshagiri, Laurence A Lasky, Chris Sander, Charles Boone, Gary D Bader, Sachdev S Sidhu
Publikováno v:
PLoS Biology, Vol 6, Iss 9, p e239 (2008)
PDZ domains are protein-protein interaction modules that recognize specific C-terminal sequences to assemble protein complexes in multicellular organisms. By scanning billions of random peptides, we accurately map binding specificity for approximatel
Externí odkaz:
https://doaj.org/article/4ed87eb30eb5451a85620aede5da754a
Autor:
Sarah G. Hymowitz, Nathaniel C. Gordon, Thuy Tran, Jeremy Johnson, Heidi J.A. Wallweber, Mary Mathieu, Robert F. Kelley, Clifford Quan, Samantha Lien, Bridget Currell, Melissa A. Starovasnik
Publikováno v:
Journal of Molecular Biology. 396:166-177
A proliferation-inducing ligand (APRIL) is a member of the tumor necrosis factor (TNF) ligand superfamily and has a proliferative effect on both normal and tumor cells. The TNF family receptors (B-cell maturation antigen (BCMA), transmembrane activat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ca6ffea641bb95d0c066d35aa85123
https://doi.org/10.1016/j.jmb.2009.11.041
https://doi.org/10.1016/j.jmb.2009.11.041
Autor:
Raffi Tonikian, Xiaofeng Xin, Dryden Bouamalay, Jingjing Li, Adrien Lugari, David E. Hill, Yun A. Shen, Aaron T. Cheng, Lianet Lopez, Jean François Rual, Alevtina Pavlenco, Barth D. Grant, David G. Drubin, Somasekar Seshagiri, Kourosh Salehi-Ashtiani, Sachdev S. Sidhu, Jackie Cheng, Charles Boone, David Gfeller, Adenrele M. Akintobi, Yingnan Zhang, Gary D. Bader, Xinping Yang, Tong Hao, Ailan Guo, Marc Vidal, Mark L. Grimes, Lin Sun, Bridget Currell
Publikováno v:
Molecular Systems Biology/Nature Publishing Group
Molecular Systems Biology
Molecular Systems Biology
The Caenorhabditis elegans SH3 domain interactome was mapped and compared with the yeast SH3 interactome. Orthologous SH3 domain-mediated interactions are highly rewired, but the general function of the SH3 domain network is conserved between the two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6e76c5895d7bd936e1301349b09571
http://hdl.handle.net/1721.1/80358
http://hdl.handle.net/1721.1/80358
Autor:
Shirley Hui, Stephen L. Sazinsky, Sachdev S. Sidhu, Bridget Currell, Gary D. Bader, Somasekar Seshagiri, Andreas Ernst, Moyez Dharsee
Publikováno v:
Science Signaling. 2
Multicellular organisms rely on complex, fine-tuned protein networks to respond to environmental changes. We used in vitro evolution to explore the role of domain mutation and expansion in the evolution of network complexity. Using random mutagenesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea54be3648e07fa5bbea5702cd73d655
https://doi.org/10.1126/scisignal.2000416
https://doi.org/10.1126/scisignal.2000416
Autor:
Christopher P. Toret, Somasekar Seshagiri, Barbara Winsor, Haiyuan Yu, Raffi Tonikian, David Gfeller, Marc Vidal, Mark Gerstein, Charles Boone, Rudolf Volkmer, Gary D. Bader, David G. Drubin, Sachdev S. Sidhu, Serena Paoluzi, Philip M. Kim, Simona Panni, Bridget Currell, Christiane Landgraf, Xiaofeng Xin, Luisa Castagnoli, Gianni Cesareni
Publikováno v:
PLoS Biology
PLoS Biology, Vol 7, Iss 10, p e1000218 (2009)
PLoS Biology, Vol 7, Iss 10, p e1000218 (2009)
A genome-scale specificity and interaction map for yeast SH3 domain-containing proteins reveal how family members show selective binding to target proteins and predicts the dynamic localization of new candidate endocytosis proteins.
SH3 domains
SH3 domains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390dbff9b3b4b68043ff731dd376b35e
https://pubmed.ncbi.nlm.nih.gov/19841731
https://pubmed.ncbi.nlm.nih.gov/19841731
Autor:
Boris Reva, Andrew C. Chan, Laurence A. Lasky, Raffi Tonikian, Xiaofeng Xin, Charles Boone, Somasekar Seshagiri, Brent A. Appleton, Yan-Yan Wu, Bridget Currell, Chris Sander, Jung-Hua Yeh, Sachdev S. Sidhu, Yingnan Zhang, Gary D. Bader, Stephen L. Sazinsky, Heike A. Held, Marie Evangelista
Publikováno v:
PLoS Biology, Vol 6, Iss 9, p e239 (2008)
PLoS Biology
PLoS Biology
PDZ domains are protein–protein interaction modules that recognize specific C-terminal sequences to assemble protein complexes in multicellular organisms. By scanning billions of random peptides, we accurately map binding specificity for approximat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c618625ddd30b6e40babbca8b2d1510
http://europepmc.org/articles/PMC2553845?pdf=render
http://europepmc.org/articles/PMC2553845?pdf=render
Autor:
Kevin P. Clark, Gábor Pál, Sachdev S. Sidhu, Mark Ultsch, Anthony A. Kossiakoff, Bridget Currell
Publikováno v:
Journal of molecular biology. 347(3)
Combinatorial shotgun alanine-scanning was used to assess intramolecular cooperativity in the high affinity site (site 1) of human growth hormone (hGH) for binding to its receptor. A total of 19 side-chains were analyzed and statistically significant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c3f4de69c12342fc202f659b658cf9
https://pubmed.ncbi.nlm.nih.gov/15755445
https://pubmed.ncbi.nlm.nih.gov/15755445
Autor:
Ming-Hong Xie, Bernard Chow, James Lee, Audrey Goddard, Daryl T. Baldwin, Yisheng Jin, Kevin P. Baker, Sherry Heldens, Guoying Yu, Paul J. Godowski, Jean Yuan, Christopher Grimaldi, Jennifer Singh, Alicia Vagts, Clarissa Chui, Dongzhou Liao, Bethanne Deuel, Austin L. Gurney, Min Zhang, Daniel G. Yansura, David Wieand, Patrick Dowd, William I. Wood, Qimin Gu, Lhney Lewis, Somasekar Seshagiri, Jill Schoenfeld, Kathryn Woods, Richard Vandlen, Laura Klimowski, Evangeline Abaya, Zemin Zhang, Melanie R. Mark, Jeremy Stinson, Edward P. Robbie, Hok Seon Kim, Victoria Smith, Craig Crowley, Jessica Foster, Laura Simmons, Bridget Currell, Stephanie Johnson, Colin K. Watanabe, Dan L. Eaton, Jennifer Brush, Jian Chen, Hilary Clark, Sothy Yi, Philip E. Hass, Celina Sanchez, Arthur J Huang
A large-scale effort, termed the Secreted Protein Discovery Initiative (SPDI), was undertaken to identify novel secreted and transmembrane proteins. In the first of several approaches, a biological signal sequence trap in yeast cells was utilized to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85bfd6259edc7f041ff31d6f8b811d17
https://europepmc.org/articles/PMC403697/
https://europepmc.org/articles/PMC403697/