Combining genomics and epidemiology to track mumps virus transmission in the United States.

Autor: Shirlee Wohl, Hayden C Metsky, Stephen F Schaffner, Anne Piantadosi, Meagan Burns, Joseph A Lewnard, Bridget Chak, Lydia A Krasilnikova, Katherine J Siddle, Christian B Matranga, Bettina Bankamp, Scott Hennigan, Brandon Sabina, Elizabeth H Byrne, Rebecca J McNall, Rickey R Shah, James Qu, Daniel J Park, Soheyla Gharib, Susan Fitzgerald, Paul Barreira, Stephen Fleming, Susan Lett, Paul A Rota, Lawrence C Madoff, Nathan L Yozwiak, Bronwyn L MacInnis, Sandra Smole, Yonatan H Grad, Pardis C Sabeti

Publikováno v: PLoS Biology, Vol 18, Iss 2, p e3000611 (2020)

Unusually large outbreaks of mumps across the United States in 2016 and 2017 raised questions about the extent of mumps circulation and the relationship between these and prior outbreaks. We paired epidemiological data from public health investigatio

Externí odkaz: https://doaj.org/article/c24d6a1103f94ea3811e45b1b7888695

Genomic Analysis of Lassa Virus during an Increase in Cases in Nigeria in 2018

Autor: Chikwe Ihekweazu, Bridget Chak, Tolulope Kayode, Peter O Okokhere, Rickey R. Shah, James Qu, Amy Gaye, Patrick Brehio, Judith U. Oguzie, Grace Okonofua, Samar B. Mehta, Daniel J. Park, John Aiyepada, Ekene B. Muoebonam, Onikepe A. Folarin, Patience Akhilomen, Michael Airende, Shirlee Wohl, Sarah M. Winnicki, Sylvanus Okogbenin, Bronwyn MacInnis, George O. Akpede, Paul E. Oluniyi, Dylan Kotliar, Mahan Nekoui, Ikponmwosa Odia, Katherine J. Siddle, Christopher Ojemiega Iruolagbe, Stephen F. Schaffner, Benevolence Ebo, Pardis C. Sabeti, Fehintola V. Ajogbasile, Jessica N. Uwanibe, Philomena Eromon, Christian T. Happi, Rachael Enigbe, Blessing Osiemi, Adrianne Gladden-Young, Iguosadolo Nosamiefan, Oyewale Tomori, Kayla G. Barnes, Mambu Momoh, Robert F. Garry, Kristian G. Andersen, Eghosa Uyigue, Catherine A. Freije, Simon Ye, Omigie Omoregie, Amber Carter, Ephraim Ogbaini-Emovon, Nathan L. Yozwiak

Publikováno v: The New England Journal of Medicine

Summary During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern among national and international public health agencies. We analyzed 220 Lassa virus genomes from infected patients, including 129 from the 2017–2018

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725baddd11368f83c893254aebf0e3e9
https://doi.org/10.1056/nejmoa1804498

Co-circulating mumps lineages at multiple geographic scales

Autor: Stephen J. Fleming, Paul A. Rota, Yonatan H. Grad, Lydia A. Krasilnikova, Katherine J. Siddle, Anne Piantadosi, Pardis C. Sabeti, Brandon Sabina, Joseph A Lewnard, Bridget Chak, Elizabeth H. Byrne, Susan Fitzgerald, Barriera P, Scott Hennigan, Daniel J. Park, Bronwyn MacInnis, Rebecca J. McNall, Stephen F. Schaffner, Hayden C. Metsky, Christian B. Matranga, Bettina Bankamp, Susan M. Lett, Meagan Burns, Nathan L. Yozwiak, Sandra Smole, Soheyla D. Gharib, Shirlee Wohl, Lawrence C. Madoff

Despite widespread vaccination, eleven thousand mumps cases were reported in the United States (US) in 2016–17, including hundreds in Massachusetts, primarily in college settings. We generated 203 whole genome mumps virus (MuV) sequences from Massa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::056cdfc85b60fb3757e4ebb062958445

Multiple introductions of Zika virus into the United States revealed through genomic epidemiology

Autor: Nathan D Grubaugh, Jason T Ladner, Moritz UG Kraemer, Gytis Dudas, Amanda L Tan, Karthik Gangavarapu, Michael R Wiley, Stephen White, Julien Thézé, Diogo M Magnani, Karla Prieto, Daniel Reyes, Andrea Bingham, Lauren M Paul, Refugio Robles-Sikisaka, Glenn Oliveira, Darryl Pronty, Hayden C Metsky, Mary Lynn Baniecki, Kayla G Barnes, Bridget Chak, Catherine A Freije, Adrianne Gladden-Young, Andreas Gnirke, Cynthia Luo, Bronwyn MacInnis, Christian B Matranga, Daniel J Park, James Qu, Stephen F Schaffner, Christopher Tomkins-Tinch, Kendra L West, Sarah M Winnicki, Shirlee Wohl, Nathan L Yozwiak, Joshua Quick, Joseph R Fauver, Kamran Khan, Shannon E Brent, Robert C Reiner, Paola N Lichtenberger, Michael Ricciardi, Varian K Bailey, David I Watkins, Marshall R Cone, Edgar W Kopp, Kelly N Hogan, Andrew C Cannons, Reynald Jean, Robert F Garry, Nicholas J Loman, Nuno R Faria, Mario C Porcelli, Chalmers Vasquez, Elyse R Nagle, Derek AT Cummings, Danielle Stanek, Andrew Rambaut, Mariano Sanchez-Lockhart, Pardis C Sabeti, Leah D Gillis, Scott F Michael, Trevor Bedford, Oliver G Pybus, Sharon Isern, Gustavo Palacios, Kristian G Andersen

Zika virus (ZIKV) is currently causing an unprecedented pandemic linked to severe congenital syndromes1,2. In July 2016, mosquito-borne ZIKV transmission was first reported in the continental United States and since then, hundreds of locally acquired

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d28138eb6a9d870583e9f6116b39c8
https://doi.org/10.1101/104794

Genomic epidemiology reveals multiple introductions of Zika virus into the United States

Autor: Derek A. T. Cummings, Christopher Tomkins-Tinch, Kelly N. Hogan, Paola Lichtenberger, Daniel Reyes, Danielle Stanek, Andrew J. Monaghan, Robert F. Garry, Adrianne Gladden-Young, Joshua Quick, Leah D Gillis, Elyse R. Nagle, Kayla G. Barnes, Cynthia Y. Luo, Karthik Gangavarapu, Carolyn M. Barcellona, Andrea M. Bingham, David I. Watkins, Marshall R. Cone, Mary Lynn Baniecki, Andrew Rambaut, James Qu, Bridget Chak, Hayden C. Metsky, Refugio Robles-Sikisaka, Nathan L. Yozwiak, Stephen F. Schaffner, Shirlee Wohl, Pardis C. Sabeti, Sarah M. Winnicki, Gytis Dudas, Diogo M. Magnani, Michael J. Ricciardi, Nuno R. Faria, Jason T. Ladner, Nathan D. Grubaugh, Moritz U. G. Kraemer, Chalmers Vasquez, Robert C. Reiner, Bronwyn MacInnis, Andreas Gnirke, Mariano Sanchez-Lockhart, Kamran Khan, Mario C. Porcelli, Kendra West, Varian K. Bailey, Andrew C. Cannons, Daniel J. Park, Scott F. Michael, Oliver G. Pybus, Glenn Oliveira, Reynald Jean, Trevor Bedford, Julien Thézé, Edgar W. Kopp, Catherine A. Freije, Michael R. Wiley, Joseph R. Fauver, Sharon Isern, Lauren M. Paul, Kristian G. Andersen, Darryl Pronty, Christian B. Matranga, Stephen White, Gustavo Palacios, Amanda L Tan, Karla Prieto, Shannon E Brent, Nicholas J. Loman

Publikováno v: Nature
Nature, Nature Publishing Group, 2017, 546 (7658), pp.401-405. ⟨10.1038/nature22400⟩
Grubaugh, N D, Ladner, JT, Kraemer, M UG, Dudas, G, Tan, A L, Gangavarapu, K, Wiley, M R, White, S, Theze, J, Magnani, D M, Prieto, K, Reyes, D, Bingham, A, Paul, L M, Robles-Sikisaka, R, Oliveira, G, Pronty, D, Barcellona, C M, Metsky, H C, Baniecki, M L, Barnes, K G, Chak, B, Freije, C A, Gladden-Young, A, Gnirke, A, Luo, C, MacInnis, B, Matranga, C B, Park, D J, Qu, J, Schaffner, S F, Christopher, T-T, West, K L, Winnicki, S M, Wohl, S, Yozwiak, N L, Quick, J, Fauver, J R, Khan, K, Brent, S E, Reiner Jr, R C, Lichtenberger, P N, Ricciardi, M, Bailey, V K, Watkins, D I, Cone, M R, Kopp IV, E W, Hogan, K N, Cannons, A C, Jean, R, Monaghan, A J, Garry, R F, Loman, N J, Faria, N R, Porcelli, M C, Vasquez, C, Nagle, E R, Cummings, D AT, Stanek, D, Rambaut, A, Sanchez-Lockhart, M, Sabeti, P C, Gillis, L D, Michael, S F, Bedford, T, Pybus, O G, Isern, S, Palacios, GF & Andersen, K G 2017, ' Genomic epidemiology reveals multiple introductions of Zika virus into the United States ', Nature, vol. 546, pp. 401–405 . https://doi.org/10.1038/nature22400

Genome sequencing of Zika virus samples from infected patients and Aedes aegypti mosquitoes in Florida shows that the virus was probably introduced into the United States on multiple occasions, and that the Caribbean is the most likely source. Three

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ae5d7e70465a2305708f75ee2f78fd