Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bridget Kluge"'
Autor:
Patrick Sarmiere, Tuija Nordstrom, Eric G. Holmberg, Bridget Kluge, Mica Gross, Fengfa Huang, Shu-xin Zhang, Suzanne Doolen
Publikováno v:
Journal of Neurotrauma. 24:411-420
Glial scar represents a physical and molecular barrier to axonal regeneration and has become an important target for regeneration research in chronic spinal cord injury. Although many methods have been proven useful for the prevention of scar formati
Autor:
Suzanne Doolen, Eric G. Holmberg, Patrick Sarmiere, Bridget Kluge, Jason White, Shu-xin Zhang
Publikováno v:
Experimental neurology. 214(1)
Statins elicit numerous favorable effects on central nervous system (CNS) injury, including inhibition of the rhoA/ROCK pathway. In the present study, we show that statins decrease acute astrocyte activation in CNS injury, and decrease chondroitin su
Publikováno v:
Journal of neurotrauma. 23(9)
Statins (3-hydroxy-3-methylglutaryl-CoA [HMG-CoA] reductase inhibitors) inhibit the rate-limiting step in the mevalonate pathway, conversion of HMG-CoA to mevalonate, by competitive inhibition with the enzyme HMG-CoA reductase. Statins not only lower
Autor:
Shuxin Zhang, Bridget Kluge, Fengfa Huang, Tuija Nordstrom, Suzanne Doolen, Mica Gross, Patrick Sarmiere, Eric G. Holmberg
Publikováno v:
Journal of Neurotrauma; Feb2007, Vol. 24 Issue 2, p411-420, 10p