Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates.

Autor: Gomaa MS; Medicinal Chemistry Division, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, UK., Lim AS, Lau SC, Watts AM, Illingworth NA, Bridgens CE, Veal GJ, Redfern CP, Brancale A, Armstrong JL, Simons C

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2012 Oct 15; Vol. 20 (20), pp. 6080-8. Date of Electronic Publication: 2012 Aug 30.

Synthesis and biological evaluation of 3-(1H-imidazol- and triazol-1-yl)-2,2-dimethyl-3-[4-(naphthalen-2-ylamino)phenyl]propyl derivatives as small molecule inhibitors of retinoic acid 4-hydroxylase (CYP26).

Autor: Gomaa MS; Medicinal Chemistry Division, Welsh School of Pharmacy, Cardiff University, King Edward VII Avenue, Cardiff CF10 3NB, United Kingdom., Bridgens CE, Veal GJ, Redfern CP, Brancale A, Armstrong JL, Simons C

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2011 Oct 13; Vol. 54 (19), pp. 6803-11. Date of Electronic Publication: 2011 Sep 08.

Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation.

Autor: Christie VB; Department of Biological Sciences, Durham University, Science Laboratories, South Road, Durham, DH1 3LE, UK., Barnard JH, Batsanov AS, Bridgens CE, Cartmell EB, Collings JC, Maltman DJ, Redfern CP, Marder TB, Przyborski S, Whiting A

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2008 Oct 07; Vol. 6 (19), pp. 3497-507. Date of Electronic Publication: 2008 Aug 08.