Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Bridgeen McMahon"'
Autor:
Ross Jeggo, David Spanswick, Eugene O'Hare, Edmund Nerou, Philip Palmer, Bridgeen McMahon, J. Mark Treherne, Hozefa Amijee, Eun-Mee Kim, David I.C. Scopes
Publikováno v:
The International Journal of Neuropsychopharmacology. 17:117-126
Prefibrillar assembly of amyloid-β (Aβ) is a major event underlying the development of neuropathology and dementia in Alzheimer's disease (AD). This study determined the neuroprotective properties of an orally bioavailable Aβ synaptotoxicity inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff252bbaf61bb05c58979e4881b9c113
https://doi.org/10.1017/s1461145713000886
https://doi.org/10.1017/s1461145713000886
Autor:
Bridgeen McMahon, Philip Palmer, Andrew D. Whyment, Edmund Nerou, T Mark Treherne, Ross Jeggo, David I.C. Scopes, Hozefa Amijee, Martyn Jones, Eugene O'Hare, Eun-Mee Kim, David Spanswick
Publikováno v:
O'Hare, E, Scopes, D I C, Kim, E-M, Palmer, P, Jones, M, Whyment, A D, Spanswick, D, Amijee, H, Nerou, E, McMahon, B, Treherne, J M & Jeggo, R 2013, ' Orally bioavailable small molecule drug protects memory in Alzheimer's disease models ', Neurobiology of Aging, vol. 34, no. 4, pp. 1116-1125 . https://doi.org/10.1016/j.neurobiolaging.2012.10.016
Oligomers of beta-amyloid (Aß) are implicated in the early memory impairment seen in Alzheimer's disease before to the onset of discernable neurodegeneration. Here, the capacity of a novel orally bioavailable, central nervous system-penetrating smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::930a79248a30fa93cf450b4e15d39877
https://pubmed.ncbi.nlm.nih.gov/23164690
https://pubmed.ncbi.nlm.nih.gov/23164690