Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Brid M. Ryan"'
Autor:
Giovanni Blandino, Roberto Dinami, Marco Marcia, Eleni Anastasiadou, Brid M. Ryan, Alina Catalina Palcau, Luigi Fattore, Giulia Regazzo, Rosanna Sestito, Rossella Loria, Ana Belén Díaz Méndez, Maria Chiara Cappelletto, Claudio Pulito, Laura Monteonofrio, George A. Calin, Gabriella Sozzi, Jit Kong Cheong, Ranit Aharonov, Gennaro Ciliberto
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-16 (2023)
Abstract The 5th Workshop IRE on Translational Oncology was held in Rome (Italy) on 27–28 March at the IRCCS Regina Elena National Cancer Institute. This meeting entitled “The New World of RNA diagnostics and therapeutics” highlightes the signi
Externí odkaz:
https://doaj.org/article/3a1f4e3c811547579a213904c93a8094
Autor:
Amelia L. Parker, Elise Bowman, Adriana Zingone, Brid M. Ryan, Wendy A. Cooper, Maija Kohonen-Corish, Curtis C. Harris, Thomas R. Cox
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-29 (2022)
Abstract Background Squamous cell carcinoma (SqCC) is a subtype of non-small cell lung cancer for which patient prognosis remains poor. The extracellular matrix (ECM) is critical in regulating cell behavior; however, its importance in tumor aggressiv
Externí odkaz:
https://doaj.org/article/33a960bc1cd646fea481743382d365e6
Autor:
Miguel García-Pardo, Amy Chang, Sabine Schmid, Mei Dong, M. Catherine Brown, David Christiani, Hilary Aurora Tindel, Paul Brennan, Chu Chen, Jie Zhang, Brid M. Ryan, David Zaridze, Matthew B. Schabath, Leticia Ferro Leal, Rui Manuel Reis, Adonina Tardon, Guillermo Fernández-Tardon, Sanjay S. Shete, Angeline Andrew, Hermann Brenner, Wei Xu, Rayjean J. Hung, Geoffrey Liu
Publikováno v:
Journal of Thoracic Oncology. 18:313-323
We explored the association of respiratory and cardiometabolic comorbidities with NSCLC overall survival (OS) and lung cancer-specific survival (LCSS), by stage, in a large, multicontinent NSCLC pooled data set.On the basis of patients pooled from 11
Autor:
Christopher E. Grant, Amy L. Flis, Leila Toulabi, Adriana Zingone, Emily Rossi, Krist Aploks, Heather Sheppard, Bríd M. Ryan
Publikováno v:
Molecular Oncology, Vol 18, Iss 6, Pp 1631-1648 (2024)
Dopamine (DA) acts in various key neurological and physiological processes as both a neurotransmitter and circulating hormone. Over the past several decades, the DA signaling network has been shown to regulate the progression of several types of soli
Externí odkaz:
https://doaj.org/article/14bcc8545fa94d06aaec7e94a26f8d35
Autor:
Margaret S. Pichardo, Tsion Zewdu Minas, Catherine M. Pichardo, Maeve Bailey-Whyte, Wei Tang, Tiffany H. Dorsey, William Wooten, Brid M. Ryan, Christopher A. Loffredo, Stefan Ambs
Publikováno v:
JAMA Network Open. 6:e2251745
ImportanceNeighborhood variables may be factors in the excessive burden of prostate cancer among African American men.ObjectiveTo examine associations between neighborhood deprivation, circulating immune-oncology markers, and prostate cancer among Af
Autor:
Sabine Schmid, Mei Jiang, M. Catherine Brown, Aline Fares, Miguel Garcia, Joelle Soriano, Mei Dong, Sera Thomas, Takashi Kohno, Leticia Ferro Leal, Nancy Diao, Juntao Xie, Zhichao Wang, David Zaridze, Ivana Holcatova, Jolanta Lissowska, Beata Świątkowska, Dana Mates, Milan Savic, Angela S. Wenzlaff, Curtis C. Harris, Neil E. Caporaso, Hongxia Ma, Guillermo Fernandez-Tardon, Matthew J. Barnett, Gary Goodman, Michael P.A. Davies, Mónica Pérez-Ríos, Fiona Taylor, Eric J. Duell, Ben Schoettker, Hermann Brenner, Angeline Andrew, Angela Cox, Alberto Ruano-Ravina, John K. Field, Loic Le Marchand, Ying Wang, Chu Chen, Adonina Tardon, Sanjay Shete, Matthew B. Schabath, Hongbing Shen, Maria Teresa Landi, Brid M. Ryan, Ann G. Schwartz, Lihong Qi, Lori C. Sakoda, Paul Brennan, Ping Yang, Jie Zhang, David C. Christiani, Rui Manuel Reis, Kouya Shiraishi, Rayjean J. Hung, Wei Xu, Geoffrey Liu
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 31, iss 3
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 31, iss 3
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Background: Somatic EGFR mutations define a subset of non–small cell lung cancers (NSCLC) that have clinical impact on NSCLC risk and outcome. However, EGFR-mutation-status is often missing in epidemiologic datasets. We developed and tested pragmat
Autor:
Choon Ping Tan, Konstantina Skourti Stathaki, Brid M Ryan, Valentí Gomez, Laura Sinigaglia, Siv Anita Hegre, Robert Habib, John J Rossi, Nagy A Habib
Publikováno v:
Cancer Research. 82:382-382
cGAS-cGAMP-STING is essential for sensing foreign DNA from pathogens or self-DNA from dying cancer cells. Activation of this pathway is critical for the innate immune response to cancer and is necessary for the full efficacy of various cancer treatme
Autor:
Lin Zhang, B. Michael Ghadim, Jochen Gaedcke, Paloma Valenzuela, Nader Hanna, Frank Bergmann, S. Perwez Hussain, Brid M Ryan, Shouhui Yang, Ohara Yuuki, Peijun He, Matthias M. Gaida, Limin Wang, Wei Tang, H. Richard Alexander
Publikováno v:
Cancer Research. 81:2860-2860
NOSTRIN represses disease aggressiveness in pancreatic cancer by suppressing eNOS-mediated NO production. We have further explored the NOSTRIN-mediated eNOS-independent pathways that contribute to its tumor inhibitory function. Gene expression analys
Autor:
Laurel A. Keefer, James R. White, Derrick E. Wood, Kelly M. R. Gerding, Kenneth C. Valkenburg, David Riley, Christopher Gault, Eniko Papp, Christine M. Vollmer, Amy Greer, James Hernandez, Paul M. McGregor, Adriana Zingone, Bríd M. Ryan, Kristen Deak, Shannon J. McCall, Michael B. Datto, James L. Prescott, John F. Thompson, Gustavo C. Cerqueira, Siân Jones, John K. Simmons, Abigail McElhinny, Jennifer Dickey, Samuel V. Angiuoli, Luis A. Diaz, Victor E. Velculescu, Mark Sausen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The genomic profiling of tumours has not been widely adopted in the clinic due to technical and practical hurdles. Here, the authors develop PGDx elio tissue complete, a scalable, standardised and FDA-cleared test comprising a targeted gene panel and
Externí odkaz:
https://doaj.org/article/e4aa27119f0a4f1f9ac75c8283f59ea8
Autor:
Sanju Sinha, Karina Barbosa, Kuoyuan Cheng, Mark D. M. Leiserson, Prashant Jain, Anagha Deshpande, David M. Wilson, Bríd M. Ryan, Ji Luo, Ze’ev A. Ronai, Joo Sang Lee, Aniruddha J. Deshpande, Eytan Ruppin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
CRISPR-Cas9 gene editing can induce a p53 mediated damage response. Here the authors investigate the possibility of selection of pre-existing cancer driver mutations during CRISPR-Cas9 knockout based gene editing and identify KRAS mutants that may co
Externí odkaz:
https://doaj.org/article/5fe16eb955dc4e7db09618e84c592388