Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

Autor: Lin, C-Y, Wolf, J, Brice, DC, Sun, Y, Locke, M, Cherry, S, Castellaw, A, Wehenkel, M, Crawford, JC, Zarnitsyna, VI, Duque, D, Allison, KJ, Allen, EK, Brown, SA, Mandarano, AH, Estepp, JH, The SJTRC Study Team, Taylor, C, Molina-Paris, C, Schultz-Cherry, S, Tang, L, Thomas, PG, McGargill, MA

Publikováno v: Cell host & microbe, vol 30, iss 1

SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to respiratory distress and death. A major unresolved question is whether prior immunity to endemic, human common cold coronaviruses (hCCCoVs) impacts susceptibility to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d8138df5e5dfb3d6a5062549c1f55b85
https://escholarship.org/uc/item/82j9q81h

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TIRTL-seq: Deep, quantitative, and affordable paired TCR repertoire sequencing.

Autor: Pogorelyy MV; St. Jude Children's Research Hospital, Memphis, TN, USA., Kirk AM; St. Jude Children's Research Hospital, Memphis, TN, USA., Adhikari S; St. Jude Children's Research Hospital, Memphis, TN, USA., Minervina AA; St. Jude Children's Research Hospital, Memphis, TN, USA., Sundararaman B; St. Jude Children's Research Hospital, Memphis, TN, USA., Vegesana K; St. Jude Children's Research Hospital, Memphis, TN, USA., Brice DC; St. Jude Children's Research Hospital, Memphis, TN, USA., Scott ZB; St. Jude Children's Research Hospital, Memphis, TN, USA., Thomas PG; St. Jude Children's Research Hospital, Memphis, TN, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 31. Date of Electronic Publication: 2024 Oct 31.

Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity.

Autor: Labombarde JG; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Pillai MR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Wehenkel M; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Lin CY; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Integrated Biomedical Sciences Program, University of Tennessee Health Science Center, Memphis, TN 38163, USA., Keating R; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Brown SA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Crawford JC; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Brice DC; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Castellaw AH; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Mandarano AH; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Guy CS; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Mejia JR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Lewis CD; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Chang TC; Center for Applied Bioinformatics, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Oshansky CM; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Wong SS; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Webby RJ; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Yan M; Department of Immunology and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Li QZ; Department of Immunology and Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Marion TN; Department of Microbiology, Immunology and Biochemistry, The University of Tennessee Health Science Center, Memphis, TN 38163, USA., Thomas PG; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., McGargill MA; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address: maureen.mcgargill@stjude.org.

Publikováno v: Cell reports [Cell Rep] 2022 Mar 08; Vol. 38 (10), pp. 110482.