Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Brice, Korkmaz"'
Autor:
Baoer Liu, Brice Korkmaz, Patricia Kraft, Tobias Mayer, Alex A. Sayour, Marc A. Grundl, Roxane Domain, Matthias Karck, Gábor Szabó, Sevil Korkmaz-Icöz
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Heart transplantation (HTX) is the standard treatment for end-stage heart failure. However, reperfusion following an ischemic period can contribute to myocardial injury. Neutrophil infiltration, along with the subsequent release o
Externí odkaz:
https://doaj.org/article/8d285453a5e744c18d6788568b1ccf1b
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Neutrophils have a critical role in the innate immune response to infection and the control of inflammation. A key component of this process is the release of neutrophil serine proteases (NSPs), primarily neutrophil elastase, proteinase 3, cathepsin
Externí odkaz:
https://doaj.org/article/e6877d781bef47b99fb331c2558d36e7
Autor:
David Cipolla, Jimin Zhang, Brice Korkmaz, James D. Chalmers, Jessica Basso, Daniel Lasala, Carlos Fernandez, Ariel Teper, Kevin C. Mange, Walter R. Perkins, Eugene J. Sullivan
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-15 (2023)
Abstract Background Brensocatib is an oral, selective, reversible inhibitor of dipeptidyl peptidase-1 (DPP-1), responsible for activating neutrophil serine proteases (NSPs) including neutrophil elastase (NE), proteinase 3 (PR3), and cathepsin G (CatG
Externí odkaz:
https://doaj.org/article/85f654da54af4f9a8406df384ca1cca2
Autor:
Sevil Korkmaz-Icöz, Sophia Abulizi, Kunsheng Li, Brice Korkmaz, Adrian-Iustin Georgevici, Alex Ali Sayour, Sivakkanan Loganathan, Hansa Canoglu, Matthias Karck, Gábor Szabó
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe shortage of available donor hearts and the risk of ischemia/reperfusion injury restrict heart transplantation (HTX). Alpha-1-antitrypsin (AAT), a well-characterized inhibitor of neutrophil serine protease, is used in augmentation ther
Externí odkaz:
https://doaj.org/article/2cc51d6ce1aa434d9a3b49caceae847b
Autor:
Qingwei Ding, Sivakkanan Loganathan, Pengyu Zhou, Alex Ali Sayour, Paige Brlecic, Tamás Radovits, Roxane Domain, Brice Korkmaz, Matthias Karck, Gábor Szabó, Sevil Korkmaz-Icöz
Publikováno v:
Journal of Surgical Research. 283:953-964
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3c515127c8cd1255b5ecd992ef9db07
https://doi.org/10.1016/j.jss.2022.11.047
https://doi.org/10.1016/j.jss.2022.11.047
Autor:
Jérôme Granel, Brice Korkmaz, Dalila Nouar, Stefanie A. I. Weiss, Dieter E. Jenne, Roxane Lemoine, Cyrille Hoarau
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Granulomatosis with polyangiitis (GPA) is a rare but serious necrotizing auto-immune vasculitis. GPA is mostly associated with the presence of Anti-Neutrophil Cytoplasmic Antibody (ANCA) targeting proteinase 3 (PR3-ANCA), a serine protease contained
Externí odkaz:
https://doaj.org/article/6b62382e37b34723b8f923559f6d54e8
Autor:
Aicha Kriaa, Vincent Mariaule, Amin Jablaoui, Soufien Rhimi, Hela Mkaouar, Juan Hernandez, Brice Korkmaz, Adam Lesner, Emmanuelle Maguin, Ali Aghdassi, Moez Rhimi
Publikováno v:
Cells, Vol 11, Iss 5, p 901 (2022)
Inflammatory bowel diseases (IBDs) have emerged as a public health problem worldwide with a limited number of efficient therapeutic options despite advances in medical therapy. Although changes in the gut microbiota composition are recognized as key
Externí odkaz:
https://doaj.org/article/2a9108f7491c45709261923b213e528e
Autor:
Jérôme Granel, Roxane Lemoine, Eric Morello, Yann Gallais, Julie Mariot, Marion Drapeau, Astrid Musnier, Anne Poupon, Martine Pugnière, Seda Seren, Dalila Nouar, Valérie Gouilleux-Gruart, Hervé Watier, Brice Korkmaz, Cyrille Hoarau
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Granulomatosis with polyangiitis (GPA) is a severe autoimmune vasculitis associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA) mainly targeting proteinase 3 (PR3), a neutrophilic serine proteinase. PR3-ANCA binding to membrane
Externí odkaz:
https://doaj.org/article/7c2203b277ea43dd8313ce7bf3093377
Autor:
Roxane Domain, Brice Korkmaz
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81094ddd84b7e4a3f0dce869e979c114
https://doi.org/10.1124/jpet.122.166110
https://doi.org/10.1124/jpet.122.166110
Autor:
Uwe Jerke, Claudia Eulenberg-Gustavus, Anthony Rousselle, Paul Nicklin, Stefan Kreideweiss, Marc A. Grundl, Peter Eickholz, Katrin Nickles, Adrian Schreiber, Brice Korkmaz, Ralph Kettritz
Publikováno v:
J Am Soc Nephrol
BACKGROUND: The ANCA autoantigens proteinase 3 (PR3) and myeloperoxidase (MPO) are exclusively expressed by neutrophils and monocytes. ANCA-mediated activation of these cells is the key driver of the vascular injury process in ANCA-associated vasculi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cc0bb09b8c21cc8e3631084260eb3df
https://doi.org/10.1681/asn.2021081112
https://doi.org/10.1681/asn.2021081112