Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Brice, Campo"'
Autor:
Myriam El Gaaloul, Andre Marie Tchouatieu, Kassoum Kayentao, Brice Campo, Benedicte Buffet, Hanu Ramachandruni, Jean Louis Ndiaye, Timothy N. C. Wells, Celine Audibert, Jane Achan, Cristina Donini, Hellen C. Barsosio, Halidou Tinto
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Malaria is preventable, but the burden of disease remains high with over 249 million cases and 608,000 deaths reported in 2022. Historically, the most important protective interventions have been vector control and chemopreventive medicines
Externí odkaz:
https://doaj.org/article/2d50668068794f068a98d794e230d076
Autor:
Alice O. Andrade, Najara Akira C. Santos, Alessandra S. Bastos, José Daniel C. Pontual, Cristiane S. Araújo, Analice S. Lima, Leandro N. Martinez, Amália S. Ferreira, Anna Caroline C. Aguiar, Carolina B. G. Teles, Rafael V. C. Guido, Rosa A. Santana, Stefanie C. P. Lopes, Jansen F. Medeiros, Zaira Rizopoulos, Joseph M. Vinetz, Brice Campo, Marcus Vinicius G. Lacerda, Maisa S. Araújo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Obtaining Plasmodium vivax sporozoites is essential for in vitro culture of liver stage parasites, not only to understand fundamental aspects of parasite biology, but also for drug and vaccine development. A major impediment to establish hig
Externí odkaz:
https://doaj.org/article/d5bcd845024949589677e9dcd17963df
Autor:
Marie Miglianico, Judith M. Bolscher, Martijn W. Vos, Karin J. M. Koolen, Marloes de Bruijni, Deeya S. Rajagopal, Emily Chen, Michael Kiczun, David Gray, Brice Campo, Robert W. Sauerwein, Koen J. Dechering
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-10 (2023)
A high-throughput screening pipeline tests the feasibility of targeting the sporozoite stage of P. falciparum through chemical interventions and identifies gramicidin as a potential sporontocidal agent.
Externí odkaz:
https://doaj.org/article/274c968724b1436f997a2540094cde1f
Autor:
Erika L. Flannery, Niwat Kangwanrangsan, Vorada Chuenchob, Wanlapa Roobsoong, Matthew Fishbaugher, Kevin Zhou, Zachary P. Billman, Thomas Martinson, Tayla M. Olsen, Carola Schäfer, Brice Campo, Sean C. Murphy, Sebastian A. Mikolajczak, Stefan H.I. Kappe, Jetsumon Sattabongkot
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 427-440 (2022)
Plasmodium vivax is a malaria-causing pathogen that establishes a dormant form in the liver (the hypnozoite), which can activate weeks, months, or years after the primary infection to cause a relapse, characterized by secondary blood-stage infection.
Externí odkaz:
https://doaj.org/article/3f99df60d3ce4a3b823a1cfa275feab1
Autor:
Yaw Aniweh, Alamissa Soulama, Jersley Chirawurah, Felix Ansah, Harry A. Danwonno, Fanta Sogore, Melanie Rouillier, Brice Campo, Lucas Amenga-Etego, Abdoulaye A. Djimde, Gordon A. Awandare, Laurent Dembele
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Malaria treatments resulted in the decline of the deadliest Plasmodium falciparum globally while species, such as P. ovale, infections have been increasingly detected across sub-Saharan Africa. Currently, no experimental drug sensitivity dat
Externí odkaz:
https://doaj.org/article/6ea99fb2cbd348e098252355a1dc3c1f
Autor:
Laura E. de Vries, Patrick A. M. Jansen, Catalina Barcelo, Justin Munro, Julie M. J. Verhoef, Charisse Flerida A. Pasaje, Kelly Rubiano, Josefine Striepen, Nada Abla, Luuk Berning, Judith M. Bolscher, Claudia Demarta-Gatsi, Rob W. M. Henderson, Tonnie Huijs, Karin M. J. Koolen, Patrick K. Tumwebaze, Tomas Yeo, Anna C. C. Aguiar, Iñigo Angulo-Barturen, Alisje Churchyard, Jake Baum, Benigno Crespo Fernández, Aline Fuchs, Francisco-Javier Gamo, Rafael V. C. Guido, María Belén Jiménez-Diaz, Dhelio B. Pereira, Rosemary Rochford, Camille Roesch, Laura M. Sanz, Graham Trevitt, Benoit Witkowski, Sergio Wittlin, Roland A. Cooper, Philip J. Rosenthal, Robert W. Sauerwein, Joost Schalkwijk, Pedro H. H. Hermkens, Roger V. Bonnert, Brice Campo, David A. Fidock, Manuel Llinás, Jacquin C. Niles, Taco W. A. Kooij, Koen J. Dechering
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Here, de Vries et al. perform a pre-clinical characterization of the antimalarial compound MMV693183: the compound targets acetyl-CoA synthetase, has efficacy in humanized mice against Plasmodium falciparum infection, blocks transmission to mosquito
Externí odkaz:
https://doaj.org/article/5a569da9aa694e86aa5e04aa0c21ba75
Autor:
Steven P. Maher, Amélie Vantaux, Victor Chaumeau, Adeline C. Y. Chua, Caitlin A. Cooper, Chiara Andolina, Julie Péneau, Mélanie Rouillier, Zaira Rizopoulos, Sivchheng Phal, Eakpor Piv, Chantrea Vong, Sreyvouch Phen, Chansophea Chhin, Baura Tat, Sivkeng Ouk, Bros Doeurk, Saorin Kim, Sangrawee Suriyakan, Praphan Kittiphanakun, Nana Akua Awuku, Amy J. Conway, Rays H. Y. Jiang, Bruce Russell, Pablo Bifani, Brice Campo, François Nosten, Benoît Witkowski, Dennis E. Kyle
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Improved control of Plasmodium vivax malaria can be achieved with the discovery of new antimalarials with radical cure efficacy, including prevention of relapse caused by hypnozoites residing in the liver of patients. We screened several com
Externí odkaz:
https://doaj.org/article/82bd81cce09f483dac02985c053a9b50
Autor:
Vijay Potluri, Radha K. Shandil, R. Gavara, Ganesh Sambasivam, Brice Campo, Sergio Wittlin, Shridhar Narayanan
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-15 (2020)
Abstract Background Emergence of anti-malarial drug resistance and perpetual increase in malaria incidence necessitates the development of novel anti-malarials. Histone deacetylases (HDAC) has been shown to be a promising target for malaria, despite
Externí odkaz:
https://doaj.org/article/b8c41fcfc5a04f1abcd296534d7dba58
Autor:
Pradeep A. Subramani, Neha Vartak-Sharma, Seetha Sreekumar, Pallavi Mathur, Bhavana Nayer, Sushrut Dakhore, Sowmya K. Basavanna, Devaiah M. Kalappa, Ramya V. Krishnamurthy, Benudhar Mukhi, Priyasha Mishra, Noriko Yoshida, Susanta Kumar Ghosh, Radhakrishan Shandil, Shridhar Narayanan, Brice Campo, Kouichi Hasegawa, Anupkumar R. Anvikar, Neena Valecha, Varadharajan Sundaramurthy
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Abstract Background Vivax malaria is associated with significant morbidity and economic loss, and constitutes the bulk of malaria cases in large parts of Asia and South America as well as recent case reports in Africa. The widespread prevalence of vi
Externí odkaz:
https://doaj.org/article/dbb1ab7ecd984ef1a6242523f8b7cfcd
Autor:
Alison Roth, Steven P. Maher, Amy J. Conway, Ratawan Ubalee, Victor Chaumeau, Chiara Andolina, Stephen A. Kaba, Amélie Vantaux, Malina A. Bakowski, Richard Thomson-Luque, Swamy Rakesh Adapa, Naresh Singh, Samantha J. Barnes, Caitlin A. Cooper, Mélanie Rouillier, Case W. McNamara, Sebastian A. Mikolajczak, Noah Sather, Benoît Witkowski, Brice Campo, Stefan H. I. Kappe, David E. Lanar, François Nosten, Silas Davidson, Rays H. Y. Jiang, Dennis E. Kyle, John H. Adams
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Currently available platforms to study liver stage of Plasmodium species have limitations. Here, the authors show that primary human hepatocyte cultures in 384-well format support hypnozoite and other liver stage development and are suitable for drug
Externí odkaz:
https://doaj.org/article/0b14f6d533014ef091394f171d42ba23