Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Briar J. Naysmith"'
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2325-2342 (2016)
Rising resistance to current clinical antibacterial agents is an imminent threat to global public health and highlights the demand for new lead compounds for drug discovery. One such potential lead compound, the peptide antibiotic teixobactin, was re
Externí odkaz:
https://doaj.org/article/c57ef8f6762f46118891477488a80c57
Autor:
Petrik Galvosas, Ian F. Hermans, Fangrong Zong, David A. J. Herman, Briar J. Naysmith, Kathryn J. Farrand, Ciaran Dolan, David E. Williams, Margaret A. Brimble, Andrew J. McGrath, Richard D. Tilley, Soshan Cheong, Jianyong Jin
Publikováno v:
Journal of Magnetism and Magnetic Materials. 439:251-258
Iron nanoparticles are highly-effective magnetic nanoparticles for T2 magnetic resonance imaging (MRI). However, the stability of their magnetic properties is dependent on good protection of the iron core from oxidation in aqueous media. Here we repo
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2325-2342 (2016)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
Rising resistance to current clinical antibacterial agents is an imminent threat to global public health and highlights the demand for new lead compounds for drug discovery. One such potential lead compound, the peptide antibiotic teixobactin, was re
Publikováno v:
Tetrahedron. 71:7137-7143
A formal total synthesis of nanaomycin D has been achieved. The strategy employed made use of a one-pot cyclisation–stereoselective reduction of a hydroxyketone to install the pyranonaphthalene moiety after execution of a Hauser–Kraus annulation
Publikováno v:
European Journal of Medicinal Chemistry. 97:816-829
Since the first reported synthesis of an α-carboline almost a century ago, there has been a steady interest in the development of strategies towards this unique heterocyclic motif. This interest can mainly be attributed to a range of biological acti
Publikováno v:
The Journal of Organic Chemistry. 79:7169-7178
A full account of our efforts toward an asymmetric synthesis of crisamicin A are presented. The key steps include a Hauser-Kraus annulation of a cyanophthalide with a chiral enone-lactone, a stereoselective cyclization-reduction to install the pyran
Publikováno v:
Tetrahedron. 70:1199-1206
The synthesis of an advanced pyranonaphthalene spiroketal as an intermediate for the total synthesis of griseusin B is described. A one-pot Hauser–Kraus annulation–methylation via reaction of a highly-substituted enone with a cyanophthalide was e
Publikováno v:
Natural product reports. 34(1)
Covering: 2008 to 2015. A review on the isolation, biological activity and synthesis of pyranonaphthoquinone natural products from 2008–2015 is provided This review discusses the isolation, biological activity and synthesis of pyranonaphthoquinone
Publikováno v:
ChemInform. 46
Since the first reported synthesis of an α-carboline almost a century ago, there has been a steady interest in the development of strategies towards this unique heterocyclic motif. This interest can mainly be attributed to a range of biological acti
Publikováno v:
ChemInform. 45
The synthesis of an advanced pyranonaphthalene spiroketal as an intermediate for the total synthesis of griseusin B is described. A one-pot Hauser–Kraus annulation–methylation via reaction of a highly-substituted enone with a cyanophthalide was e