Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Brianne, Dentel"'
Autor:
Jennifer M. Gibson, Anthony Hernandez Vazquez, Kunihiko Yamashiro, Vikram Jakkamsetti, Chongyu Ren, Katherine Lei, Brianne Dentel, Juan M. Pascual, Peter T. Tsai
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113533- (2023)
Summary: Cerebellar dysfunction has been linked to autism spectrum disorders (ASDs). Although cerebellar pathology has been observed in individuals with fragile X syndrome (FXS) and in mouse models of the disorder, a cerebellar functional contributio
Externí odkaz:
https://doaj.org/article/3a39af370f964470a5d947f514fe3734
Autor:
Brianne Dentel, Lidiette Angeles-Perez, Chongyu Ren, Vikram Jakkamsetti, Andrew J. Holley, Daniel Caballero, Emily Oh, Jay Gibson, Juan M. Pascual, Kimberly M. Huber, Benjamin P. Tu, Peter T. Tsai
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104334- (2022)
Summary: Targeted therapies for epilepsies associated with the mTORC1 signaling negative regulator GATOR1 are lacking. NPRL2 is a subunit of the GATOR1 complex and mutations in GATOR1 subunits, including NPRL2, are associated with epilepsy. To deline
Externí odkaz:
https://doaj.org/article/56ade3a392ee4d319319c6e00f7820c4
Autor:
Nicolas Loof, Olaf Stüve, Darin T. Okuda, Peter T. Tsai, Emily Herndon, Brianne Dentel, Petra D. Cravens, Rehana Z. Hussain, Richard Doelger, Michael K. Racke
Publikováno v:
Annals of Clinical and Translational Neurology. 5:1543-1561
Objective Natalizumab blocks α4-integrin-mediated leukocyte migration into the central nervous system (CNS). It diminishes disease activity in multiple sclerosis (MS), but carries a high risk of progressive multifocal encephalopathy (PML), an opport
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d2553cd1b59cdc9d3efd539b365767d
https://doi.org/10.1002/acn3.664
https://doi.org/10.1002/acn3.664
Publikováno v:
Neuron. 104:1032-1033
Dysregulated mTOR contributes to neurodevelopmental dysfunction. A new study (Chen et al., 2019) demonstrates that suppression of mTORC2, not mTORC1, ameliorates survival, seizures, and abnormal behaviors in a Pten mutant model, highlighting mTORC2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b1942fcad9419741823db7164224bd5
https://doi.org/10.1016/j.neuron.2019.11.026
https://doi.org/10.1016/j.neuron.2019.11.026
Autor:
Rehana Z, Hussain, Petra C, Cravens, Richard, Doelger, Brianne, Dentel, Emily, Herndon, Nicolas, Loof, Peter, Tsai, Darin T, Okuda, Michael K, Racke, Olaf, Stüve
Publikováno v:
Annals of Clinical and Translational Neurology
Objective Natalizumab blocks α4‐integrin‐mediated leukocyte migration into the central nervous system (CNS). It diminishes disease activity in multiple sclerosis (MS), but carries a high risk of progressive multifocal encephalopathy (PML), an op
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b0bd8fb436bed287094badaaa9a9826b
https://pubmed.ncbi.nlm.nih.gov/30564621
https://pubmed.ncbi.nlm.nih.gov/30564621