Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brianna M. Brooks"'
Autor:
Brianna M. Brooks, Manisha Pradhan, Yu-Shan Cheng, Kirill Gorshkov, Atena Farkhondeh, Catherine Z. Chen, Jeanette Beers, Chengyu Liu, Karsten Baumgaertel, Steven Rodems, Wei Zheng
Publikováno v:
Stem Cell Research, Vol 54, Iss , Pp 102447- (2021)
Alagille syndrome (ALGS) is a rare autosomal dominant disorder caused by disruption of the Notch signaling pathway due to mutations in either JAGGED1 (JAG1) (ALGS type 1) or NOTCH2 (ALGS type 2). Loss of this signaling interferes with the development
Externí odkaz:
https://doaj.org/article/2f12baeebb87454e85e831c61b5e858d
Autor:
Brianna M. Brooks, Charles D. Yeh, Jeanette Beers, Chengyu Liu, Yu-Shan Cheng, Kirill Gorshkov, Jizhong Zou, Wei Zheng, Catherine Z. Chen
Publikováno v:
Stem Cell Research, Vol 53, Iss , Pp 102387- (2021)
Farber disease is an ultra-rare lysosomal storage disease. Mutations in the N-acylsphingosine amidohydrolase (ASAH1) gene, which encodes for the enzyme acid ceramidase (ACDase), cause ceramides to accumulate in the body. A human induced pluripotent s
Externí odkaz:
https://doaj.org/article/21065c45040d4145a00f1c144a7784bb
Autor:
Catherine Z. Chen, Paul Shinn, Zina Itkin, Richard T. Eastman, Robert Bostwick, Lynn Rasmussen, Ruili Huang, Min Shen, Xin Hu, Kelli M. Wilson, Brianna M. Brooks, Hui Guo, Tongan Zhao, Carleen Klump-Thomas, Anton Simeonov, Samuel G. Michael, Donald C. Lo, Matthew D. Hall, Wei Zheng
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Drug repurposing is a rapid approach to identify therapeutics for the treatment of emerging infectious diseases such as COVID-19. To address the urgent need for treatment options, we carried out a quantitative high-throughput screen using a SARS-CoV-
Externí odkaz:
https://doaj.org/article/6fdf6eea16ad4d56b94f2a702c53b35f
Autor:
Steven Rodems, Kirill Gorshkov, Catherine Z. Chen, Brianna M. Brooks, Manisha Pradhan, Wei Zheng, Jeanette Beers, Yu-Shan Cheng, Chengyu Liu, Karsten Baumgaertel, Atena Farkhondeh
Publikováno v:
Stem Cell Research, Vol 54, Iss, Pp 102447-(2021)
Stem cell research
Stem cell research
Alagille syndrome (ALGS) is a rare autosomal dominant disorder caused by disruption of the Notch signaling pathway due to mutations in either JAGGED1 (JAG1) (ALGS type 1) or NOTCH2 (ALGS type 2). Loss of this signaling interferes with the development
Autor:
Hui Guo, Brianna M. Brooks, Paul Shinn, Zina Itkin, Kelli M. Wilson, Catherine Z. Chen, Richard T. Eastman, Wei Zheng, Donald C. Lo, Min Shen, Robert Bostwick, Ruili Huang, Tongan Zhao, Matthew D. Hall, Carleen Klump-Thomas, Lynn Rasmussen, Xin Hu, Samuel G. Michael, Anton Simeonov
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2021)
Frontiers in Pharmacology, Vol 11 (2021)
Drug repurposing is a rapid approach to identifying therapeutics for the treatment of emerging infectious diseases such as COVID-19. To address the urgent need for treatment options, we carried out a quantitative high-throughput screen using a SARS-C
Autor:
Wei Zheng, Kirill Gorshkov, Charles D. Yeh, Chengyu Liu, Jeanette Beers, Jizhong Zou, Yu-Shan Cheng, Brianna M. Brooks, Catherine Z. Chen
Publikováno v:
Stem cell research
Stem Cell Research, Vol 53, Iss, Pp 102387-(2021)
Stem Cell Research, Vol 53, Iss, Pp 102387-(2021)
Farber disease is an ultra-rare lysosomal storage disease. Mutations in the N-acylsphingosine amidohydrolase (ASAH1) gene, which encodes for the enzyme acid ceramidase (ACDase), cause ceramides to accumulate in the body. A human induced pluripotent s